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| 1 | The Transforming Growth Factor-β Superfamily Member Growth-Differentiation Factor-15 Protects the Heart From Ischemia/Reperfusion Injury显示文摘 | Tibor Kempf Matthias Eden Jens Strelau Marian Naguib Christian Willenbockel J?rn Tongers J?rg Heineke Daniel Kotlarz Jian Xu Jeffery D. Molkentin Hans W. Niessen Helmut Drexler Kai C. Wollert | 2006 | Circulation Research2006，，3： | 3 |
| 2 | Numerical Analysis of a System of Singularly Perturbed Convection-Diffusion Equations Related to Optimal Control显示文摘We consider an optimal control problem with an 1D singularly perturbed differential state equation.For solving such problems one uses the enhanced system of the state equation and its adjoint form.Thus,we obtain a system of two convectiondiffusion equations.Using linear finite elements on adapted grids we treat the effects of two layers arising at different boundaries of the domain.We proof uniform error estimates for this method on meshes of Shishkin type.We present numerical results supporting our analysis. | Hans-Görg Roos Christian Reibiger | 2011 | Numerical Mathematics(Theory,Methods and Applications)2011，4，4： | 3 |
| 3 | Applying Methods from Differential Geometry to Devise Stable and Persistent Air Layers Attached to Objects Immersed in Water显示文摘We describe a few mathematical tools which allow to investigate whether air-water interfaces exist(under prescribedconditions)and are mechanically stable and temporally persistent.In terms of physics,air-water interfaces are governed by theYoung-Laplace equation.Mathematically they are surfaces of constant mean curvature which represent solutions of a nonlinearelliptic partial differential equation.Although explicit solutions of this equation can be obtained only in very special cases,it is-under moderately special circumstances-possible to establish the existence of a solution without actually solving thedifferential equation.We also derive criteria for mechanical stability and temporal persistence of an air layer.Furthermorewe calculate the lifetime of a non-persistent air layer.Finally,we apply these tools to two examples which exhibit the symmetriesof 2D lattices.These examples can be viewed as abstractions of the biological model represented by the aquatic fernSalvinia. | Wilfried Konrad Christian Apeltauer Jrg Frauendiener Wilhelm Barthlott Anita Roth-Nebelsick | 2009 | Journal of Bionic Engineering2009，6，4： | 3 |
| 4 | Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: the CELIM randomised phase 2 trial显示文摘 | Gunnar Folprecht Thomas Gruenberger Wolf O Bechstein Hans-Rudolf Raab Florian Lordick J?rg T Hartmann Hauke Lang Andrea Frilling Jan Stoehlmacher Jürgen Weitz Ralf Konopke Christian Stroszczynski Torsten Liersch Detlev Ockert Thomas Herrmann Eray Goekkurt | 2010 | Lancet Oncology2010，，1： | 3 |
| 5 | National Forest Inventories capture the multifunctionality of managed forests in Germany显示文摘Background:Forests perform various important ecosystem functions that contribute to ecosystem services.In many parts of the world,forest management has shifted from a focus on timber production to multi-purpose forestry,combining timber production with the supply of other forest ecosystem services.However,it is unclear which forest types provide which ecosystem services and to what extent forests primarily managed for timber already supply multiple ecosystem services.Based on a comprehensive dataset collected across 150 forest plots in three regions differing in management intensity and species composition,we develop models to predict the potential supply of 13 ecosystem services.We use those models to assess the level of multifunctionality of managed forests at the national level using national forest inventory data.Results:Looking at the potential supply of ecosystem services,we found trade-offs(e.g.between both bark beetle control or dung decomposition and both productivity or soil carbon stocks)as well as synergies(e.g.for temperature regulation,carbon storage and culturally interesting plants)across the 53 most dominant forest types in Germany.No single forest type provided all ecosystem services equally.Some ecosystem services showed comparable levels across forest types(e.g.decomposition or richness of saprotrophs),while others varied strongly,depending on forest structural attributes(e.g.phosphorous availability or cover of edible plants)or tree species composition(e.g.potential nitrification activity).Variability in potential supply of ecosystem services was only to a lesser extent driven by environmental conditions.However,the geographic variation in ecosystem function supply across Germany was closely linked with the distribution of main tree species.Conclusions:Our results show that forest multifunctionality is limited to subsets of ecosystem services.The importance of tree species composition highlights that a lack of multifunctionality at the stand level can be compensated by managing forests at the landscape level,when stands of complementary forest types are combined.These results imply that multi-purpose forestry should be based on a variety of forest types requiring coordinated planning across larger spatial scales. | Nadja K.Simons María R.Felipe-Lucia Peter Schall Christian Ammer Jürgen Bauhus Nico Blüthgen Steffen Boch François Buscot Markus Fischer Kezia Goldmann Martin M.Gossner Falk Hänsel Kirsten Jung Peter Manning Thomas Nauss Yvonne Oelmann Rodica Pena Andrea Polle Swen C.Renner Michael Schloter Ingo Schöning Ernst-Detlef Schulze Emily F.Solly Elisabeth Sorkau Barbara Stempfhuber Tesfaye Wubet Jörg Müller Sebastian Seibold Wolfgang W.Weisser | 2021 | Forest Ecosystems2021，8，1： | 2 |
| 6 | Environmental implications of the magnetic record in Pleistocene lacustrine sediments of the Qaidam Basin, NE Tibetan Plateau显示文摘 | Christian Herb Weilin Zhang Andreas Koutsodendris Erwin Appel Xiaomin Fang J?rg Pross | 2013 | Quaternary International2013，，： | 2 |
| 7 | Budesonide Is Effective in Adolescent and Adult Patients With Active Eosinophilic Esophagitis显示文摘 | Alex Straumann Sebastien Conus Lukas Degen Stephanie Felder Mirjam Kummer Hansjürg Engel Christian Bussmann Christoph Beglinger Alain Schoepfer Hans–Uwe Simon | 2010 | Gastroenterology2010，，： | 2 |
| 8 | Voxel-based analyses of magnetization transfer imaging of the brain in hepatic encephalopathy显示文摘AIM: To evaluate the spatial distribution of cerebral abnormalities in cirrhotic subjects with and without hepatic encephalopathy (HE) found with magnetization transfer imaging (MTI).METHODS: Nineteen cirrhotic patients graded from neurologically normal to HE grade 2 and 18 healthy control subjects underwent magnetic resonance imaging. They gave institutional-review-board-approved written consent. Magnetization transfer ratio (MTR) maps were generated from MTI. We tested for significant differences compared to the control group using statistical non-parametric mapping (SnPM) for a voxelbased evaluation.RESULTS: The MTR of grey and white matter was lower in subjects with more severe HE. Changes were found in patients with cirrhosis without neurological defi cits in the basal ganglia and bilateral white matter. The loss in magnetization transfer increased in severity and spatial extent in patients with overt HE. Patients with HE grade 2 showed an MTR decrease in white and grey matter: the maximum loss of magnetization transfer effect was located in the basal ganglia [SnPM (pseudo-)t = 17.98, P = 0.0001].CONCLUSION: The distribution of MTR changes in HE points to an early involvement of basal ganglia and white matter in HE. | Falk R Miese Hans-Jrg Wittsack Gerald Kircheis Arne Holstein Christian Mathys Ulrich Mdder Mathias Cohnen | 2009 | World Journal of Gastroenterology2009，15，41： | 2 |
| 9 | FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer (FIRE-3): a randomised, open-label, phase 3 trial显示文摘 | Volker Heinemann Ludwig Fischer von Weikersthal Thomas Decker Alexander Kiani Ursula Vehling-Kaiser Salah-Eddin Al-Batran Tobias Heintges Christian Lerchenmüller Christoph Kahl Gernot Seipelt Frank Kullmann Martina Stauch Werner Scheithauer J?rg Hielscher | 2014 | Lancet Oncology2014，，10： | 2 |
| 10 | Intraoperative laser fluorescence angiography in colorectal surgery: a noninvasive analysis to reduce the rate of anastomotic leakage显示文摘 | Stefanie Kudszus Christian Roesel Alexander Schachtrupp J?rg J. H?er | 2010 | Langenbeck’s Archives of Surgery2010，，8： | 2 |
| 11 | Truncating mutations in Peutz-Jeghers syndrome are associated with more polyps, surgical interventions and cancers显示文摘 | Heidi Salloch Anke Reinacher-Schick Karsten Schulmann Christian Pox J?rg Willert Andrea Tannapfel Stefan Heringlake Timm O. Goecke Stefan Aretz Susanne Stemmler Wolff Schmiegel | 2010 | International Journal of Colorectal Disease2010，，1： | 2 |
| 12 | Population Pharmacokinetic Modeling of Hydromorphone in Cardiac Surgery Patients during Postoperative Pain Therapy显示文摘 | Christian Jeleazcov Teijo I. Saari Harald Ihmsen Jan Mell Katharina Fr?hlich Ljubica Krajinovic J?rg Fechner Jürgen Schüttler | 2014 | Anesthesiology2014，，2： | 2 |
| 13 | Rat and rabbit oral devel- opmental toxicology studies with two perfluorinated compounds 显示文摘 | Case MT York RG Christian MS | 2001 | Int J Toxicol2001，20，2： | 1 |
| 14 | Trichoderma populations from alkaline agricultural soil in the Nile valley, Egypt, consist of only two species显示文摘 | Youssuf Gherbawy Irina Druzhinina Gihan M. Shaban Michael Wuczkowsky Manal Yaser Mohamed A. El-Naghy Hans-J?rg Prillinger Christian P. Kubicek | 2004 | Mycological Progress2004，，3： | 1 |
| 15 | Chemoradiotherapy with capecitabine versus fluorouracil for locally advanced rectal cancer: a randomised, multicentre, non-inferiority, phase 3 trial显示文摘 | Ralf-Dieter Hofheinz Frederik Wenz Stefan Post Axel Matzdorff Stephan Laechelt J?rg T Hartmann Lothar Müller Hartmut Link Markus Moehler Erika Kettner Elisabeth Fritz Udo Hieber Hans Walter Lindemann Martina Grunewald Stephan Kremers Christian Constantin | 2012 | Lancet Oncology2012，，6： | 1 |
| 16 | Migrational changes of mesenchymal stem cells in response to cytokines, growth factors, hypoxia, and aging显示文摘 | Yahaira Naaldijk Adiv A. Johnson Stefan Ishak Hans J?rg Meisel Christian Hohaus Alexandra Stolzing | 2015 | Experimental Cell Research2015，，1： | 1 |
| 17 | Light weight construction for heavy machinery显示文摘 | J RG H CHRISTIAN P | 2004 | Thyssen Krupp Tecforum2004，，12： | 1 |
| 18 | Modeling and closo edloop control of hypnosis by means of bispectral index (BIS) with isoflurane显示文摘 | Andrea G Marco RG Christian W | 2001 | IEEE Trans Biomed Eng2001，48，： | 1 |
| 19 | Ion transport and barrier function are disturbed in microscopic colitis显示文摘 | Christian Barmeyer Irene Erko Anja Fromm Christian Bojarski Kristina Allers Verena Moos Martin Zeitz Michael Fromm J?rg‐Dieter Schulzke | 2012 | Annals of the New York Academy of Sciences2012，，1： | 1 |
| 20 | Selection, Characterization and X-ray Structure of Anti-ampicillin Single-chain Fv Fragments from Phage-displayed Murine Antibody Libraries显示文摘 | J?rg Burmester Silvia Spinelli Luisa Pugliese Anke Krebber Annemarie Honegger Sabine Jung Bernhard Schimmele Christian Cambillau Andreas Plückthun | 2001 | Journal of Molecular Biology2001，，3： | 1 |
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