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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 2 | Acute ischaemic stroke interventions: large vessel occlusion and beyond显示文摘Care for acute ischaemic stroke is one of the most rapidly evolving fields due to the robust outcomes achieved by mechanical thrombectomy.Large vessel occlusion(LVO)accounts for up to 38%of acute ischaemic stroke and comes with devastating outcomes for patients,families and society in the pre-intervention era.A paradigm shift and a breakthrough brought mechanical thrombectomy back into the spotlight for acute ischaemic stroke;this was because five randomised controlled trials from several countries concluded that mechanical thrombectomy for acute stroke offered overwhelming benefits.This review article will present a comprehensive overview of LVO management,techniques and devices used,and the future of stroke therapy.In addition,we review our institution experience of mechanical thrombectomy for posterior and distal circulation occlusion. | Ahmad Sweid Batoul Hammoud Sunidhi Ramesh Daniella Wong Tyler D Alexander Joshua Harrison Weinberg Maureen Deprince Jaime Dougherty Dimitri Jean-Mickael Maamari Stavropoula Tjoumakaris Hekmat Zarzour Michael R Gooch Nabeel Herial Victor Romo David M Hasan Robert H Rosenwasser Pascal Jabbour | 2020 | Stroke & Vascular Neurology2020，5，1： | 2 |
| 3 | Contractile responses to human urotensinⅡin rat and human pulmonary arteries: effect of endothelial factors and chronic hypoxia in the rat显示文摘 | Maclean M R Alexander D Atirrat A | 2000 | Br J Pharmacol2000，130，2： | 2 |
| 4 | An infertile male with dilated seminal vesicles due to functional obstruction显示文摘 | Michael D Font Alexander W Pastuszak John R Case Larry I Lipshult | 2017 | Asian Journal of Andrology2017，19，2： | 2 |
| 5 | Twenty proteins containing a C terminal SOCS box form five structural classes 显示文摘 | Hilton D J Richardson R T Alexander W S | 1998 | Proc Natl Acad Sci1998，95，1： | 2 |
| 6 | 脊髓损伤后残存自主神经功能载录国际标准显示文摘近年来,脊髓损伤神经学分类园际标准(International Stand- ards for the Neurological Classification of Spinal Cord Injury, ISNCSCI)被用来记载脊髓损伤后运动和感觉功能的损害,目前该标准已是第六版。1992年第一份国际认可的标准出版时,曾进行了较大的修订,修订内容包括完全性损伤与不完全性损伤的定义, | MS Alexander AB Jackson W Donovan DE Graves SL Elliott A Krassioukov AW Sheel I Estoresl B Green A Gousse NL Braekett D Cardenas M Kennelly A-K Karlason F Biering-Sorensen K Krogh T Linsenmeyer R Marino J Ditunno CJ Mathias I Perkash G Creasey G Schilero J Wecht B Schurch V Dietz J Sonksen S Stiens D Bodner LA Wuermser J-J Wyndaele 周谋望 刘楠 S Charlifue | 2010 | 中华物理医学与康复杂志2010，32，4： | 2 |
| 7 | High Near-infrared Reflectivity Modulation with Polycrystalline Electrochromic WO3 Films显示文摘 | GOLDNER R B MENDELSOHN D H ALEXANDER J | 1983 | Appl Phy Lett1983，43，12： | 1 |
| 8 | Human parathyroid hormone 1-34 reverses bone loss in ovariectomized mice显示文摘 | Alexander JM Bab I Fish S Muller R Uchiyama T Gronowicz G Nahounou M Zhao Q White DW Chorev M Gazit D Rosenblatt M | | 0，，： | 1 |
| 9 | Sediment accumu lation in a modern epieontinental-shelf setting: the Yellow Sea 显示文摘 | Alexander C R DeMaster D J Nittrouer C A | 1991 | Marine Geology1991，98，1： | 1 |
| 10 | Relative per- formance of normal and modified protein(opaque-2) maize hybrids 显示文摘 | Lambert R J Alexander D E Dudley J W | 1969 | Crop Sci1969，9，2： | 1 |
| 11 | Carbon catalysed hydrogen exchange in petroleum source rocks显示文摘 | Alexander R Dawson D Pierce K | 2009 | Organic Geochemistry2009，40，9： | 1 |
| 12 | Twenty proteins containing a C-terminal SOCS box form five structural classes显示文摘 | Hilton D J Richardson R T Alexander W S | 1998 | Proc Natl Acad Sci1998，95，1： | 1 |
| 13 | Coordinate gene activity in response to agents that in- duce systemic acquired resistance显示文摘 | WARD E R UKNESS S J WILLIAMS S C DINCHER S S WIEDER- HOLD D L ALEXANDER D C AHL-GOY P METRAUX J P RYALS J A | 1991 | Plant Cell1991，3，10： | 1 |
| 14 | Inversion control in sugarcane juice with sodium Metasilieate显示文摘 | Alexander G B Acin N D Zapata R M | 1971 | Proc Int Soc Sugarcane Technol1971，13，： | 1 |
| 15 | A New Classification of Thoracolumbar Injuries: The Importance of Injury Morphology, the Integrity of the Posterior Ligamentous Complex, and Neurologic Status显示文摘 | Alexander R. Vaccaro Ronald A. Lehman R John Hurlbert Paul A. Anderson Mitchel Harris Rune Hedlund James Harrop Marcel Dvorak Kirkham Wood Michael G. Fehlings Charles Fisher Steven C. Zeiller D Greg Anderson Christopher M. Bono Gordon H. Stock Andrew K. B | 2005 | Spine2005，，20： | 1 |
| 16 | Active set support vector regression显示文摘 | Musicant D R Feinberg Alexander | 2004 | IEEE Transactions on Neural Networks2004，15，2： | 1 |
| 17 | Sediment ac cumulation in a modern epicontinental shelf setting: The Yellow Sea显示文摘 | Alexander C R DeMaster D J Nittrouer C A | 1991 | Marine Geology1991，98，1： | 1 |
| 18 | Preliminary evaluation of hemagglutination and hemagglutination inhibition tests for avian infectious bronchitis virus显示文摘 | ALEXANDER D J BRACEWELL C D GOUGH R E | 1976 | Avian Pathology1976，5，： | 1 |
| 19 | Antigenic diversity and similarities detected in avian paramyxovirus type 1 (Newcastle disease virus) isolates using monoclonal antibod- ies显示文摘 | Alexander D J Manvell R J Lowings J P | 1997 | Avian Pathol1997，26，2： | 1 |
| 20 | The effect of source and maturity on the stable isotopic compositions of individual hydrocarbons in sediments and crude oils from the Vulcan Sub-basin, Timor Sea, Northern Australia 显示文摘 | Dawson D Grice K Alexander R | 2007 | Organic Geochemistry2007，38，7： | 1 |
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