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| 1 | 急性脊髓损伤患者治疗的临床操作指南:关于MRI基线在临床治疗决策与结果预测中作用的几点建议(英文)显示文摘The objective of this guideline is to outline the role of magnetic resonance imaging(MRI) in clinical decision making and outcome prediction in patients with traumatic spinal cord injury(SCI).Methods A systematic review of the literature was conducted to address key questions related to the use of MRI in patients with traumatic SCI.This review focused on longitudinal studies that controlled for baseline neurologic status.A multidisciplinary Guideline Development Group(GDG) used this information,their clinical expertise,and patient input to develop recommendations on the use of MRI for SCI patients.Based on GRADE(Grading of Recommendation,Assessment,Development and Evaluation),a strong recommendation is worded as ' we recommend,' whereas a weaker recommendation is indicated by 'we suggest.' Results Based on the limited available evidence and the clinical expertise of the GDG,our recommendations were:(1) 'We suggest that MRI be performed in adult patients with acute SCI prior to surgical intervention,when feasible,to facilitate improved clinical decision-making'(quality of evidence,very low) and(2) 'We suggest that MRI should be performed in adult patients in the acute period following SCI,before or after surgical intervention,to improve prediction of neurologic outcome '(quality of evidence,low).Conclusions These guidelines should be implemented into clinical practice to improve outcomes and prognostication for patients with SCI. | Fehlings MG Martin AR Tetreault LA Aarabi B Anderson P Arnold PM Brodke D Burns AS Chiba K Dettori JR Furlan JC Hawryluk G Holly LT Howley S Jeji T Kalsi-Ryan S Kotter M Kurpad S Kwon BK Marino RJ Massicotte E Merli G Middleton JW Nakashima H Nagoshi N Palmieri K Singh A Skelly AC Tsai EC Vaccaro A Wilson JR Yee A Harrop JS | 2017 | 中华神经外科疾病研究杂志2017，16，6： | 8 |
| 2 | 一种新型的高频半导体量子点单电子泵显示文摘除了直流负电压外,还在浅法刻蚀出的GaAs/AlGaAs量子线上的两个金属指形门上分别叠加两个相位相差π的正弦信号,从而对形成量子点的两个势垒作不等幅调制.在无源漏偏压的情况下,通过周期形成的量子点实现了单电子的搬运.由于新的半导体量子点单电子泵不是依赖库仑阻塞效应通过隧穿进行单电子输运,因此,该器件就不会受到固定隧穿时间引起的低工作频率限制.在1.7K温度下,频率达到3GHz仍然可以观测到量子化电流平台,对应的电流值达到0.5nA量级.这种新器件提供了实现高速度、高精度搬运单电子的另一种可能途径. | 李玲 Kaestner B Blumenthal M D Giblin S Janssen T J B M Pepper M Anderson D Jones G Ritchie D A 高洁 | 2008 | 物理学报2008，57，3： | 4 |
| 3 | Quality of life, work productivity impairment and healthcare resources in inflammatory bowel diseases in Brazil显示文摘BACKGROUND Inflammatory bowel diseases(IBD)have been associated with a low quality of life(QoL)and a negative impact on work productivity compared to the general population.Information about disease control,patient-reported outcomes(PROs),treatment patterns and use of healthcare resources is relevant to optimizing IBD management.AIM To describe QoL and work productivity and activity impairment(WPAI),treatment patterns and use of healthcare resources among IBD patients in Brazil.METHODS A multicenter cross-sectional study included adult outpatients who were previously diagnosed with moderate to severe Crohn’s disease(CD)or ulcerative colitis(UC).At enrolment,active CD and UC were defined as having a Harvey Bradshaw Index≥8 or a CD Activity Index≥220 or calprotectin>200μg/g or previous colonoscopy results suggestive of inadequate control(per investigator criteria)and a 9-point partial Mayo score≥5,respectively.The PRO assessment included the QoL questionnaires SF-36 and EQ-5D-5L,the Inflammatory Bowel Disease Questionnaire(IBDQ),and the WPAI questionnaire.Information about healthcare resources and treatment during the previous 3 years was collected from medical records.Chi-square,Fisher’s exact and Student’s t-/Mann-Whitney U tests were used to compare PROs,treatment patterns and the use of healthcare resources by disease activity(α=0.05).RESULTS Of the 407 patients in this study(CD/UC:64.9%/35.1%,mean age 42.9/45.9 years,54.2%/56.6%female,38.3%/37.1%employed),44.7%/25.2%presented moderate-to-severe CD/UC activity,respectively,at baseline.Expressed in median values for CD/UC,respectively,the SF-36 physical component was 46.6/44.7 and the mental component was 45.2/44.2,the EQ-visual analog scale score was 80.0/70.0,and the IBDQ overall score was 164.0/165.0.Moderate to severe activity,female gender,being unemployed,a lower educational level and lower income were associated with lower QoL(P<0.05).Median work productivity impairment was 20%and 5%for CD and UC patients,respectively,and activity impairment was 30%,the latter being higher among patients with moderate to severe disease activity compared to patients with mild or no disease activity(75.0%vs 10.0%,P<0.001).For CD/UC patients,respectively,25.4%/2.8%had at least one surgery,38.3%/19.6%were hospitalized,and 70.7%/77.6%changed IBD treatment at least once during the last 3 years.The most common treatments at baseline were biologics(75.3%)and immunosuppressants(70.9%)for CD patients and 5-ASA compounds(77.5%)for UC patients.CONCLUSION Moderate to severe IBD activity,especially among CD patients,is associated with a substantial impact on QoL,work productivity impairment and an increased number of IBD surgeries and hospitalizations in Brazil. | Rogerio Serafim Parra Julio MF Chebli Heda MBS Amarante Cristina Flores Jose ML Parente Odery Ramos Milene Fernandes Jose JR Rocha Marley R Feitosa Omar Feres Antonio S Scotton Rodrigo B Nones Murilo M Lima Cyrla Zaltman Carolina D Goncalves Isabella M Guimaraes Genoile O Santana Ligia Y Sassaki Rogerio S Hossne Mauro Bafutto Roberto LK Junior Mikaell AG Faria Sender J Miszputen Tarcia NF Gomes Wilson R Catapani Anderson A Faria Stella CS Souza Rosana F Caratin Juliana T Senra Maria LA Ferrari | 2019 | World Journal of Gastroenterology2019，25，38： | 2 |
| 4 | Precision atomic gravimeter based on Bragg diffraction显示文摘 | P A Altin M T Johnsson V Negnevitsky G R Dennis R P Anderson J E Debs S S Szigeti K S Hardman S Bennetts G D McDonald L D Turner J D Close N P Robins | 2013 | New Journal of Physics2013，，2： | 2 |
| 5 | Managing soil moisture on waste burial sites in add regions 显示文摘 | Anderson J E Nowak R S Ratzlaff T D | 1992 | Journal of Environmental Quality1992，22，1： | 1 |
| 6 | GENI design principles 显示文摘 | Peterson L Anderson T Blumenthal D | 2006 | IEEE Computer2006，39，9： | 1 |
| 7 | FCC regenerator flow model显示文摘 | SAPRE A V LEIB T M ANDERSON D H | 1990 | Chemical Engineering Science1990，45，8： | 1 |
| 8 | A novel proteasome inhibitor NPI-0052 as an anticancer therapy显示文摘 | Chauhan D Hideshima T Anderson K C | 2006 | British J Cancer2006，95，8： | 1 |
| 9 | Naphthalene and benzene degradation under Fe(Ⅲ)-reducing conditions in petroleum-contaminated aquifers显示文摘 | Anderson R T Lovley D R | 1999 | Bioremediation Journal1999，3，2： | 1 |
| 10 | Scatterometer data inter- pretation: derivation of the transfer function CMOD4 显示文摘 | Stoffelen A C M Anderson D L T | 1997 | Journal of Geophysical Research1997，102，3： | 1 |
| 11 | Relation of vitamin D deficiency to cardiovascular risk factors, disease status, and incident events in a general healtheare population 显示文摘 | ANDERSON J L MAY H T HORNE B D | 2010 | Am J Cardio12010，106，7： | 1 |
| 12 | Geologic Stereo Mapping of Geologic Structure with Spot Satellite Data 显示文摘 | Berger Z Lee T H Anderson D W | 1992 | AAPG Bulletin1992，7，6： | 1 |
| 13 | Ultrastructural morphmetric analysis of BrucelIa abortus-infected trophoblasts in experimental placentitis显示文摘 | Anderson T D Cheville N F | 2006 | Pathol2006，124，： | 1 |
| 14 | GENI design principles 显示文摘 | Peterson L Anderson T Blumenthal D | 2006 | Computer2006，39，9： | 1 |
| 15 | TVA:A DoS-limiting network architecture显示文摘 | Yang X W Wetherall D Anderson T | 2008 | IEEE/ACM Transactions on Networking2008，16，6： | 1 |
| 16 | Studies into the formation of dioxins in the sintering process used in the iron and steel industry: characterization of isomer profiles in particulate and gaseous Emissions显示文摘 | WANG T S ANDERSON D R THOMPSON D | 2003 | Chemosphere2003，51，7： | 1 |
| 17 | Chain termination in polyhydroxyalkanoate synthesis: Involvement of exogenous hydroxy-compounds as chain transfer agents显示文摘 | Madden L A Anderson A J Shah D T | 1999 | Int J Biol Macromol1999，25，13： | 1 |
| 18 | A DoS-limiting显示文摘 | YANG X WETHERALL D ANDERSON T | 2006 | Computer Research and Development2006，43，3： | 1 |
| 19 | A prospective,randomized trial of intravenous fat emulsion administration in trauma victims requiring total parenteral nutrition显示文摘 | Battistella F D Widergren J T Anderson J T | 1997 | J Trauma1997，43，1： | 1 |
| 20 | Influence of chain ordering on the selectivity of dipalmitoylphosphatidylcholine bilayer membranes for permeant size and shape显示文摘 | Xiang T X Anderson B D | 1998 | Biophys J1998，75，6： | 1 |
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