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| 1 | Endoscopy and polyps-diagnostic and therapeutic advances in management显示文摘Despite multiple efforts aimed at early detection through screening, colon cancer remains the third leading cause of cancer-related deaths in the United States, with an estimated 51000 deaths during 2013 alone. The goal remains to identify and remove benign neoplastic polyps prior to becoming invasive cancers. Polypoid lesions of the colon vary widely from hyperplastic, hamartomatous and inflammatory to neoplastic adenomatous growths. Although these lesions are all benign, they are common, with up to one-quarter of patients over 60 years old will develop pre-malignant adenomatous polyps. Colonoscopy is the most effective screening tool to detect polyps and colon cancer, although several studies have demonstrated missed polyp rates from 6%-29%, largely due to variations in polyp size. This number can be as high as 40%, even with advanced (> 1 cm) adenomas. Other factors including sub-optimal bowel preparation, experience of the endoscopist, and patient anatomical variations all affect the detection rate. Additional challenges in decision-making exist when dealing with more advanced, and typically larger, polyps that have traditionally required formal resection. In this brief review, we will explore the recent advances in polyp detection and therapeutic options. | Scott R Steele Eric K Johnson Bradley Champagne Brad Davis Sang Lee David Rivadeneira Howard Ross Dana A Hayden Justin A Maykel | 2013 | World Journal of Gastroenterology2013，19，27： | 16 |
| 2 | 男性性功能障碍、男性不育与神经系统疾病之间的关系显示文摘正常的性功能和生殖功能很大程度上依赖于神经系统功能的正常发挥。男性神经系统受损可导致勃起功能障碍、射精障碍和精液异常,进而导致不育。出现这些受损的主要原因有盆腔和腹腔损伤、糖尿病、先天性脊柱异常,多发性硬化症和脊髓受损。勃起功能障碍已经可以通过越来越具侵入式的治疗方法而有所改善,从药物疗法、注射疗法到外科的阴茎植入术。病情较轻的逆行射精患者可以用药物来逆转条件进行治疗,对病情较重的患者,则在射精后从其膀胱中收取精液。对于中度的不射精者,可以采用药物治疗:而对于严重者,则可采用阴茎震荡刺激和电射精等辅助射精技术。假如这些措施都失败了,可尝试采用手术方法取精液。对于一些脊髓受损的男性,假如环境条件和精液质量足够好,可在家中采用阴茎震荡刺激,然后将精液放入伴侣阴道内。其他方法就要求助于辅助生殖技术了,包括宫内受精和体外受精(用ICSI或者不用)。选用何种方法在很大程度上依赖于患者精液中活性精子的数量。 | Mikkel Fode Sheila Krogh-Jespersen Nancy L Brackett Dana A Ohl Charles M Lynne Jens Sonksen | 2012 | Asian Journal of Andrology2012，14，1： | 7 |
| 3 | Protective role of PI3-kinase/Akt/eNOS signaling in mechanical stress through inhibition of p38 mitogenactivated protein kinase in mouse lung显示文摘 | Xin-qi PENG Mahendra DAMARLA Jarrett SKIRBALL Stephanie NONAS Xiao-ying WANG Eugenia J HAN Emile J HASAN Xuan CAO Adel BOUEIZ Rachel DAMICO Rubin M TUDER Alfred M SClUTO Dana R ANDERSON Joe GNGARCIA David A KASS Paul M HASSOUN Jun-tian ZHANG | 2010 | Acta Pharmacologica Sinica2010，31，2： | 6 |
| 4 | 低密度脂蛋白和高密度脂蛋白相对全蛋黄溶液在猕猴精子低温冷冻中的作用显示文摘最近,住各种动物精子低温冷冻的实验中,提取于鸡蛋蛋黄中的低密度脂蛋白被视为优于全蛋黄溶液。与此同时,有研究认为蛋黄中的高密度脂蛋白可能对解冻后精子的生存产生负面影响。关于低密度脂蛋白和高密度脂蛋白在猕猴精子低温冷冻作用的研究还未有过报道。本研究在加和不加渗透型抗冻剂(甘油)两种情况下,通过与全蛋黄溶液对比的手段评价了两种脂蛋白在猕猴精子低温冷冻中的作用。此外,本研究也尝试多种能够改造精于膜与低密度脂蛋白结合体成分的添加剂对保存解冻精子活力的作用。我们的实验结果表明,低密度脂蛋白是伞蛋黄溶液在猕猴精子低温冷冻中发挥保护作用的主要成分。不管有无添加甘油,低密度脂蛋白与令蛋黄溶液在保存解冻精子活性方面作用相近,并未显现出任何优越性。通过加入胆同醇、胆固醇环糊精复合物或卵磷脂来改变精子膜与低密度脂蛋白结合体成分的方法并未改善解冻精子的存活状况;但加入甲基-β-环糊精则明显降低解冻精于的活力。高密度脂蛋白对猕猴精子低温冷冻保存不存在负面影响。对猕猴精子低温冷冻保存而言,本研究表明全蛋黄溶液相比较于稀释液中的有效成分低密度脂蛋白仍然具有优越性。 | Qiao-Xiang Dong Sarah E Rodenburg Dana Hill Catherine A VandeVoort | 2011 | Asian Journal of Andrology2011，13，3： | 4 |
| 5 | 食物是良药:将食物和营养融入医疗保健服务的行动显示文摘Sarah Downer及其同事探讨在医疗保健服务体系中将食品和营养纳入膳食相关疾病的预防、管理和治疗的新举措。与膳食相关的慢性病的全球流行,促使人们尝试将改善饮食作为患者医疗和护理的正规举措。 | Sarah Downer Seth A Berkowitz Timothy S Harlan Dana Lee Olstad Dariush Mozaffarian 冯琳(译) 武阳丰(校) | 2021 | 英国医学杂志中文版2021，24，4： | 2 |
| 6 | Effective use of FibroTest to generate decision trees in hepatitis C显示文摘AIM:To assess the usefulness of FibroTest to forecast scores by constructing decision trees in patients with chronic hepatitis C.METHODS:We used the C4.5 classification algorithm to construct decision trees with data from 261 patients with chronic hepatitis C without a liver biopsy.The FibroTest attributes of age,gender,bilirubin,apolipoprotein,haptoglobin,α2 macroglobulin,and γ-glutamyl transpeptidase were used as predictors,and the FibroTest score as the target.For testing,a 10-fold cross validation was used.RESULTS:The overall classification error was 14.9%(accuracy 85.1%).FibroTest's cases with true scores of F0 and F4 were classified with very high accuracy(18/20 for F0,9/9 for F0-1 and 92/96 for F4) and the largest confusion centered on F3.The algorithm produced a set of compound rules out of the ten classification trees and was used to classify the 261 patients.The rules for the classification of patients in F0 and F4 were effective in more than 75% of the cases in which they were tested.CONCLUSION:The recognition of clinical subgroups should help to enhance our ability to assess differences in fibrosis scores in clinical studies and improve our understanding of fibrosis progression. | Dana Lau-Corona Luís Alberto Pineda Héctor Hugo Avilés Gabriela Gutiérrez-Reyes Blanca Eugenia Farfan-Labonne Rafael Núez-Nateras Alan Bonder Rosalinda Martínez-García Clara Corona-Lau Marco Antonio Olivera-Martínez Maria Concepción Gutiérrez-Ruiz Guillermo Robles-Díaz David Kershenobich | 2009 | World Journal of Gastroenterology2009，15，21： | 2 |
| 7 | The preconditioning phenomenon: atool for the scientist or a clinical reality 显示文摘 | Yellon DM Dana A | 2000 | Circ Res2000，87，7： | 1 |
| 8 | Prevalence of dry eye syndrome among US women显示文摘 | Debra A Schaumberg David A Sullivan Julie E Buring M.Reza Dana | 2003 | American Journal of Ophthalmology2003，，2： | 1 |
| 9 | Quality improvement guidelines for percutaneous transhepatic cholangiography and biliary drainage显示文摘 | Dana R Curtis A John F | 2003 | J Vasc Interv Radiol2003，14，92： | 1 |
| 10 | Verruciform Xanthoma in the setting of ctaneous trauma and chronic inflamation:report of a patient and a brief review of the literature显示文摘 | Cumberland L Dana A Resh B | 2010 | J Cutan Pathol2010，37，8： | 1 |
| 11 | Vernjciform Xanthoma i' theSelling of cutaneous strauma and chronic inflammation : report of apa-lient and af)Hef review of the literature 显示文摘 | Cumberland L Dana A ReshH el al | 2010 | J Culan Pathol2010，37，8： | 1 |
| 12 | Mesencephalic dopaminergic neurons in primary cultures express functional neurotensin re ceptors 显示文摘 | Brouard A Pelaprat D Dana C | 1992 | J Neurosci1992，12，4： | 1 |
| 13 | Prevention of work-related disability显示文摘 | Feldstein A Breen V Dana N | 1998 | Am J Prey Med1998，14，3： | 1 |
| 14 | Instruments and methods for measuring the backward-scattering coefficient of ocean waters 显示文摘 | Robert A Maffione David R Dana | 1997 | Appl Opt1997，36，24： | 1 |
| 15 | The HITRAN 2008 molecular spectroscopic database 显示文摘 | Rothman L S Gordon I E Barbe A ChrisBenner D Bernath P F Birk M Boudon V Brown L R Campargue A Champi-on J P Chance K Coudert L H Dana V Devi V M Fally S Flaud J M Gamache R R Goldman A Jacquemart D Klein er I Lacome N Lafferty W J Mandin J Y Massie S T Mikhailenko S N Miller C E Moazzen A N Naumenko 0 VNikitin A V Orphal J Perevalov V I Perrin A Predoi C A Rinsland C P Rotger M ime kovd M Smith M A H Sung K Tashkun S A Tennyson J Toth R A Vandaele A C Vander A J | 2009 | Journal of Quantitative Spectroscopy Radiative Transfer2009，110，： | 1 |
| 16 | Fuel recovery from waste oily sludge using solvent extraction, process safety and environmental 显示文摘 | Essam A H Zubaidy Dana M Abouelnasr | 2010 | Protection2010，88，： | 1 |
| 17 | Functional Outcomes for Surgically Treated 3- and 4-part Proximal Humerus Fractures显示文摘 | Wild Jason R. DeMers Ariana French Robert Shipps Melanie R. Bergin Patrick F. Musapatika Dana Jelen Bradley A | 2011 | Orthopedics (Online)2011，，10： | 1 |
| 18 | Data transmission over networks for estimation and control显示文摘 | GUPTA V DANA A F HESPANHA J P | 2009 | IEEE Transactions on Automatic Control2009，54，8： | 1 |
| 19 | Adenosine A1receptor induced delayed preconditioning in rabbits: induction of p38 MAPK activation and HSP27 phosphorylation via a tyrosine kinase and protein kinase C - dependent mechanism显示文摘 | Dana A Skarli M Papakrivopoulou J | 2000 | Circ Res2000，86，： | 1 |
| 20 | Adenosine A1 receptor activation induces delayed preconditioning in rats mediated by manganese supetoxide dismutase显示文摘 | Dana A Jonassen AK Yamashita N | 2000 | Circulation2000，101，24： | 1 |
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