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| 1 | 国际癌症研究机构工作组乳腺癌筛查简报显示文摘乳腺癌是导致全球女性死亡最常见的恶性肿瘤之一,而且超过一半发生在低至中等收入的国家。近年来在我国,特别是大中城市及沿海经济发展较快地区,乳腺癌已排在女性恶性肿瘤的第一位,是危害妇女健康的主要疾病。如何在早期筛查乳腺癌,以提高防癌效果,对社区及临床有重要意义。本期世界全科医学工作嘹望对2015—06-03在线发表于《新英格兰杂志》的《国际癌症研究机构(IARC)工作组乳腺癌筛查简报》进行了部分翻译,IARC对经乳腺钼靶X线摄影检查筛查乳腺癌的利弊进行了细致评估后,推荐50~69岁女性接受筛查利大于弊。同时,简报还对一般人群及乳腺癌高危人群采取不同方法进行乳腺癌筛查的利弊相关证据评价进行了总结,对全科医生和临床医师筛查工作提供了借鉴。 | Béatrice Lauby-Secretan Chiara Scoccianti Dana Loomis Lamia Benbrahim-Tallaa Véronique Bouvard Franca Bianchini Kurt Straif | 2015 | 中国全科医学2015，18，27： | 2 |
| 2 | NKX2-3 and IRGM variants are associated with diseasesu sceptibility to IBD in Eastern European patients显示文摘AIM: To investigate variants of immunity-related GT-Pase family M (IRGM) and NKX2-3 genes and genotype-phenotype in Eastern European patients with inflammatory bowel disease (IBD).METHODS: We analyzed 1707 Hungarian and Czech subjects with Crohn’s disease (CD) (n = 810, age: 37.1 ± 12.6 years, duration: 10.7 ± 8.4 years) and ulcerative colitis (UC) (n = 428, age: 43.7 ± 15.0 years, duration: 12.6 ± 9.9 years), as well as 469 healthy controls. IRGM rs13361189, NKX2-3 rs10883365 and ECM1 rs13294 polymorphisms were tested by LightCy-cler allele discrimination. Detailed clinical phenotypes were determined by reviewing the medical charts. RESULTS: NKX2-3 rs10883365 variant allele was as-sociated with increased risk for CD (P = 0.009, OR = 1.24, 95% CI = 1.06-1.48) and UC (P = 0.001, OR = 1.36, 95% CI = 1.13-1.63), whereas variant IRGM allele increased risk for CD (P = 0.029, OR = 1.36, 95% CI = 1.03-1.79). In contrast, ECM1 rs13294 was not associat-ed with either CD or UC. In CD, the variant IRGM allele was associated with a colon-only location (P = 0.02, OR = 1.62, 95% CI = 1.07-2.44), whereas in UC, the ECM1 variant was associated with cutaneous manifestations (P = 0.002, OR = 3.36, 95% CI = 1.48-7.63). Variant alleles did not predict resistance to steroids or azathio-prine, efficacy of infliximab, or need for surgery. CONCLUSION: NKX2-3 and IRGM are susceptibility locifor IBD in Eastern European patients. Further studies are needed to confirm the reported phenotype-genotype associations. | Nora Meggyesi Lajos S Kiss Magdalena Koszarska Martin Bortlik Dana Duricova Laszlo Lakatos Tamas Molnar Martin Lenicek Libor Vítek Istvan Altorjay Maria Papp Zsolt Tulassay Pal Miheller Janos Papp Attila Tordai Hajnalka Andrikovics Milan Lukas Peter Laszlo Lakatos | 2010 | World Journal of Gastroenterology2010，16，41： | 2 |
| 3 | Fraudulent Financial Reporting: Consideration of Industry Traits and Corporate Governance Mechanisms 显示文摘 | Beasley M S Joseph V Carcello Dana R Hemlanson Paul D Lapides | 2000 | Accounting Horizons2000，14，4： | 1 |
| 4 | Prevention of work-related disability显示文摘 | Feldstein A Breen V Dana N | 1998 | Am J Prey Med1998，14，3： | 1 |
| 5 | The HITRAN 2008 molecular spectroscopic database 显示文摘 | Rothman L S Gordon I E Barbe A ChrisBenner D Bernath P F Birk M Boudon V Brown L R Campargue A Champi-on J P Chance K Coudert L H Dana V Devi V M Fally S Flaud J M Gamache R R Goldman A Jacquemart D Klein er I Lacome N Lafferty W J Mandin J Y Massie S T Mikhailenko S N Miller C E Moazzen A N Naumenko 0 VNikitin A V Orphal J Perevalov V I Perrin A Predoi C A Rinsland C P Rotger M ime kovd M Smith M A H Sung K Tashkun S A Tennyson J Toth R A Vandaele A C Vander A J | 2009 | Journal of Quantitative Spectroscopy Radiative Transfer2009，110，： | 1 |
| 6 | Data transmission over networks for estimation and control显示文摘 | GUPTA V DANA A F HESPANHA J P | 2009 | IEEE Transactions on Automatic Control2009，54，8： | 1 |
| 7 | Association of pericentric inversion of chromosome 9 and infertility in romanian population显示文摘 | Dana M Stoian V | 2012 | Maedica(Buchar)2012，7，1： | 1 |
| 8 | Age and Racial Variation in Central Corneal Thickness of Preschool and School-aged Children显示文摘 | Haider Kathryn M Mickler Casey Oliver Dana Moya Frank J Cruz Oscar A Davitt Bradley V | 2008 | Journal of Pediatric Ophthalmology and Strabismus2008，，4： | 1 |
| 9 | An analysis of multinational “audit failures”显示文摘 | Heather M Hermanson Dana R Hermanson Joseph V Carcello | 1996 | International Journal of Accounting1996，，3： | 1 |
| 10 | Comparison of methods of DNA extraction from stream sediment显示文摘 | Leff L G Dana J R McArthur J V Shimkets L J 1995 | 1995 | A pplied and Environmental Microbiology1995，61，： | 1 |
| 11 | Comparison of methods of DNA extraction from stream sediments显示文摘 | LEFF L G DANA J R McArthur J V | 1995 | Applied and Environmental Microbiology1995，61，3： | 1 |
| 12 | Antimicrobial resistance and bacterial identification utilizing a microelectronic chip array显示文摘 | Lorelei W Carolyn M Dana V | 2001 | J Clin Microbiol2001，39，3： | 1 |
| 13 | Levels of perfluorooc- tanesulfonate (PFOS) and perfluorooetanoate (PFOA) in blood samples from different groups of adults living in Greece 显示文摘 | IRENE V DANAE C ANGELIKI F | 2012 | Chemosphere2012，80，10： | 1 |
| 14 | Carcinogenicity of trichloroethylene, tetrachloroethylene, some other chlorinated solvents, and their metabolites显示文摘 | Neela Guha Dana Loomis Yann Grosse Béatrice Lauby-Secretan Fatiha El Ghissassi Véronique Bouvard Lamia Benbrahim-Tallaa Robert Baan Heidi Mattock Kurt Straif | 2012 | Lancet Oncology2012，，12： | 1 |
| 15 | Association of pericenlric inversion of chromosome 9 and infertility in romanian population显示文摘 | DANA M STOIAN V | 2012 | Maedica (Buchar)2012，7，1： | 1 |
| 16 | Antimicrobial resistance and bacterial identification utilizing a microelectronic chip array显示文摘 | Lorelei W Carolyn R Dana V | 2001 | J Clin Microbiol2001，39，3： | 1 |
| 17 | Bilirubin/Albumin Ratio for predicting acute bilirubin-induced neurologic dysfunction显示文摘 | Ardakani S B Dana V G Ziaee V | 2011 | Iran J Pediatr2011，21，1： | 1 |
| 18 | Developments in oil shale in 1989显示文摘 | Knutson C F Dana G F Kattai V | 1990 | AAPG1990，74，10： | 1 |
| 19 | UV-curable pressure sensitive adhesive films:Effects of biocompatible plasticizers on mechanical and adhesion properties显示文摘 | Dana S F Nguyen D V Kochhar J S | 2013 | Soft Matter2013，9，27： | 1 |
| 20 | An instrumented remotely operated vehicle for measuring inherent and apparent optical properties of the sea显示文摘 | Dana D V Voss J M | 1993 | SPIE1993，2048，： | 1 |
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