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| 1 | Chronic constipation in hemiplegic patients显示文摘AIM: To assess the prevalence of bowel dysfunction in hemiplegic patients, and its relationship with the site of neurological lesion, physical immobilization and pharmacotherapy. METHODS: Ninety consecutive hemiplegic patients and 81 consecutive orthopedic patients were investigated during physical motor rehabilitation in the same period, in the same center and on the same diet. All subjects were interviewed ≥ 3 mo after injury using a questionnaire inquiring about bowel habits before injury and at the time of the interview. Patients’ mobility was evaluated by the Adapted Patient Evaluation Conference System. Drugs considered for the analysis were nitrates, angiogenic converting enzyme (ACE) inhibitors, calcium antagonists, anticoagulants, antithrombotics, antidepressants, anti-epileptics. RESULTS: Mobility scores were similar in the two groups. De novo constipation (OR = 5.36) was a frequent outcome of the neurological accident. Hemiplegics showed an increased risk of straining at stool (OR: 4.33), reduced call to evacuate (OR: 4.13), sensation of incomplete evacuation (OR: 3.69), use of laxatives (OR: 3.75). Logistic regression model showed that constipation was significantly and independently associated with hemiplegia. A positive association was found between constipation and use of nitrates and antithrombotics in both groups. Constipation was not related to the site of brain injury. CONCLUSION: Chronic constipation is a possible outcome of cerebrovascular accidents occurring in 30% of neurologically stabilized hemiplegic patients. Its onset after a cerebrovascular accident appears to be independent from the injured brain hemisphere, and unrelated to physical inactivity. Pharmacological treatment with nitrates and antithrombotics may represent an independent risk factor for developing chronic constipation. | F Bracci D Badiali P Pezzotti G Scivoletto U Fuoco L Di Lucente A Petrelli E Corazziari | 2007 | World Journal of Gastroenterology2007，13，29： | 15 |
| 2 | 酒精摄入、心脏生物标志物和心房颤动风险与不良结局显示文摘酒精摄入和新发心房颤动相关性证据不一,尤其是在低剂量下。该研究评估欧洲队列在整个饮酒范围内酒精摄入、生物标志物和新发心房颤动的关系。方法和结果:在一个以社区为基础的汇集队列中,研究者随访107845人,以评估酒精摄入(酒精种类和饮酒方式)与新发心房颤动的关系。研究者收集经典心血管病危险因素和新发心力衰竭的信息,并检测生物标记物氨基末端脑钠肽前体和高敏肌钙蛋白I。 | 陈嘉睿(译) 练桂丽((审校) Csengeri D Sprünker NA Di Castelnuovo A Niiranen T Vishram-Nielsen JK Costanzo S S derberg S Jensen SM Vartiainen E Donati MB Magnussen C Camen S Gianfagna F L chen ML Kee F Kontto J Mathiesen EB Koenig W Stefan B de Gaetano G J rgensen T Kuulasmaa K Zeller T Salomaa V Iacoviello L Schnabel RB | 2021 | 中华高血压杂志2021，29，2： | 9 |
| 3 | Comparison of Wirsung-jejunal duct-tomucosa and dunking technique for pancreatojejunostomy after pancreatoduodenectomy显示文摘Pancreato-enteric reconstruction after pancreatoduodenectomy (PD) is still a source of debate because of the high incidence of complications. Among the various types of pancreato-jejunostomies we don’t know yet which is the best in terms of anastomotic failure and related complications rates. Wirsung-jejunal duct-to-mucosa anastomosis (WJ) and 'dunking' pancreato-jejunal anastomosis (DPJ) are the two most used ones worldwide but conflicting results are reported. To determine which is the safer anastomosis and to define when an anastomosis should be preferred, we retrospectively reviewed two groups of patients who underwent WJ or DPJ. METHODS:Twenty-three patients underwent PD with WJ (n=17) with dilated (WJD) (n=9) or not-dilated Wirsung’s duct (WJND) (n=8) or with a DPJ (n=6) over a 3-year period at a single institution. RESULTS: The complications rate was high in all groups of patients (33.3% in WJD, 37.5% in WJND and 66.7% in DPJ). A pancreatic fistula developed in one patient in each group (11. 1% in WJD, 12. 5% in WJND and 16. 7% in DPJ). All these patients were managed conservatively. Anastomotic disruption took place in the WJ patients especially in the WJND group (n=2) compared to the WJD (n=1) (25% vs 11.1%) or DPJ groups (0%) : these three patients required a re-operation. Overall, the anastomotic defects were higher in patients who underwent WJND (37.5%), compared to WJD (22.2%) and to DPJ (16.7%). However, no statistical differences were found among the groups. Delayed gastric emptying (DGE) and total parenteral nutrition (TPN) along with anastomotic defects were responsible for a prolonged hospital stay. CONCLUSIONS:Our results were not able to demonstrate any statistical difference between the two different techniques in preventing anastomotic failure. WJ can represent a valid choice in case of a dilated duct and a firm, fibrotic enlarged gland that could not be properly invaginated in a small jejunal loop. DGE may occur in those patients who experienced an anastomotic failure and required a TPN regimen with a prolonged hospital stay. | Unita di Chirurgia, Dipartimento di Fisiopatologia Clinica (Batignani G, Fratini G, Zuckermann M and Tonelli F) and Dipartimento di Statistica (Bianchini E), Universitd degli Studi di Firenze, Flo rence, Italy | 2005 | Hepatobiliary & Pancreatic Diseases International2005，4，3： | 9 |
| 4 | ConservativeapproachinPeutz-JeghersSyndrome:Single-balloon enteroscopyandsmallbowelpolypectomy显示文摘AIM: To assess the usefulness of the balloon assisted enteroscopy in preventing surgical intervention in pa-tients with Peutz-Jeghers syndrome (PJS) having a small bowel large polyps. METHODS: Seven consecutive asymptomatic pts(age 15-38 years) with PJS have been collected; six under-went polypectomy using single balloon enteroscopy(Olympus SIF Q180) with antegrade approach using push and pull technique. SBE system consists of the SIF-Q180 enteroscope, an overtube balloon control unit(OBCU Olympus Balloon Control Unit) and a dispos-able silicone splinting tube with balloon(ST-SB1). All procedures were performed under general anesthesia. Previously all pts received wireless capsule endos-copy(WCE). Prophylactic polypectomy was reservedmainly in pts who had polyps > 15 mm in diameter. The balloon is inflated and deflated by a balloon control unit with a safety pressure setting range from-6.0 kPa to +5.4 kPa. Informed consent has been obtained from pts or parents for each procedure.RESULTS: Six pts underwent polypectomy of small bowel polyps; in 5 pts a large polyp > 15 mm(range 20-50 mm in diameter) was resected; in 1 patient with WCE negative, SBE was performed for previous surgi-cal resection of gastrointestinal stromal tumors. In 2 pts endoscopic clips were placed due to a polypectomy. No surgical complication have been reported. SBE with resection of small bowel large polyps in PJS pts was useful to avoid gastrointestinal bleeding and emergency laparotomy due to intestinal intussuscep-tions. No gastrointestinal tumors were found in sub-sequent enteroscopic surveillance in all seven pts. In order surveillance, all pts received WCE, upper en-doscopy, ileocolonoscopy every 2 years. No pts had extraintestinal malignant lesions. SBE was performed when WCE was positive for significant polyps(> 15 mm).CONCLUSION: The effective of prophylactic polyp-ectomy of small bowel large polyps(> 15 mm) could be the first line treatment for conservative approach in management of PJS patients. | Torroni F Romeo E Rea F De Angelis P Foschia F Faraci S Federici di Abriola G Contini AC Caldaro T Dall’Oglio L | 2014 | World Journal of Gastrointestinal Endoscopy2014，6，7： | 7 |
| 5 | TCR engagement regulates differential reponsiveness of human memory T cells to FasL (CD95)-mediated apoptosis 显示文摘 | Di Somma M M Somma F Montani M S G | 1999 | J Immunology1999，162，1： | 1 |
| 6 | Value of lymph node assessment in ovarian cancer:Status of the art at the end of the second millennium显示文摘 | DI TE F BAIOCCHI G | 2000 | Int J gynecol Cancer2000，10，6： | 1 |
| 7 | New simple and rapid method for purification of mesenchy- mal stem cells from the human umbilical cord Wharton jelly显示文摘 | Montanucci P G Basta T Pescara I Pennoni F Di Giovanni and R Calafiore | 2011 | Tis- sue Eng Part A2011，，： | 1 |
| 8 | Vulvovaginitis in childhood显示文摘 | Dei M Di Maggio F Di Paolo G | 2010 | Best Pract Res Clin Obstet Gynaecol2010，24，2： | 1 |
| 9 | Body mass index-independent metabolic alterations in narcolepsy with cataplexy 显示文摘 | Poli F Plazzi G Di Dalmazi G | 2009 | Sleep2009，32，11： | 1 |
| 10 | Thoracic pedicle subtraction osteotomy in the treatment of severe pediatric deformities显示文摘 | Bakaloudis G Lolli F Di Silvestre M | 2011 | Eur Spine J2011，201，： | 1 |
| 11 | Antiplatelet therapy in patients receiving aortic bioprostheses: a report of clinical and instrumental safety显示文摘 | di Marco F Grendene S Feltrin G | 2007 | J Thorac Card iovasc Surg2007，133，6： | 1 |
| 12 | Diffusion-weighted MR imaging in the evaluation of renal tumours显示文摘 | Squillaci E Manenti G Di Stefano F | 2004 | J Exp Clin Cancer Res2004，23，1： | 1 |
| 13 | Electroluminescence of silicon nanocrystals in MOS structures显示文摘 | Franzò G Irrera A Moreira E C Miritello M Iacona F Sanfilippo D Di Stefano G Fallica P G Priolo F | | 0，，： | 1 |
| 14 | Geological impact of some tailing dams in Sardinia,Italy显示文摘 | Di G F Massoli-Novelli R G | 1992 | Environmental Geology and Water Sciences1992，19，3： | 1 |
| 15 | Degenerative lumbar scoliosis in elderly patients:dynamic stabilization without fusion versus posterior instrumented fusion显示文摘 | Di Silvestre M Lolli F Bakaloudis G | 2014 | Spine J2014，1，： | 1 |
| 16 | Time-dependent attractor for the oscillon equation显示文摘 | DI PLINIO F DUANE G S TEMAM R | 2011 | Discrete Contin Dyn Syst2011，29，： | 1 |
| 17 | Bovine lacto ferrin for Helicobacter pylori eradication: an open, randomized, muhicentre study显示文摘 | DI MARIO F ARAGONA G DAL BO N | 2006 | Aliment Pharmacol Ther2006，23，8： | 1 |
| 18 | Use of small-bore as large bore chest tubes for treatment of maligant pleural offusions显示文摘 | Parulekar W Di Primio G Matzinger F | 2001 | Chest2001，120，1： | 1 |
| 19 | White noise analysis for L6vy processes 显示文摘 | DI NUNNO G ФKSENDAL B PROSKE F | 2004 | Journal of Functional Analysis2004，206，1： | 1 |
| 20 | ANG II increases TIMP-1 expression in rat aortic smooth muscle cells in vivo显示文摘 | Castoldi G Di Gioia CR Pieruzzi F | 2003 | Am J Physiol Heart Circ Physiol2003，284，2： | 1 |
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