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| 1 | Chronic constipation in hemiplegic patients显示文摘AIM: To assess the prevalence of bowel dysfunction in hemiplegic patients, and its relationship with the site of neurological lesion, physical immobilization and pharmacotherapy. METHODS: Ninety consecutive hemiplegic patients and 81 consecutive orthopedic patients were investigated during physical motor rehabilitation in the same period, in the same center and on the same diet. All subjects were interviewed ≥ 3 mo after injury using a questionnaire inquiring about bowel habits before injury and at the time of the interview. Patients’ mobility was evaluated by the Adapted Patient Evaluation Conference System. Drugs considered for the analysis were nitrates, angiogenic converting enzyme (ACE) inhibitors, calcium antagonists, anticoagulants, antithrombotics, antidepressants, anti-epileptics. RESULTS: Mobility scores were similar in the two groups. De novo constipation (OR = 5.36) was a frequent outcome of the neurological accident. Hemiplegics showed an increased risk of straining at stool (OR: 4.33), reduced call to evacuate (OR: 4.13), sensation of incomplete evacuation (OR: 3.69), use of laxatives (OR: 3.75). Logistic regression model showed that constipation was significantly and independently associated with hemiplegia. A positive association was found between constipation and use of nitrates and antithrombotics in both groups. Constipation was not related to the site of brain injury. CONCLUSION: Chronic constipation is a possible outcome of cerebrovascular accidents occurring in 30% of neurologically stabilized hemiplegic patients. Its onset after a cerebrovascular accident appears to be independent from the injured brain hemisphere, and unrelated to physical inactivity. Pharmacological treatment with nitrates and antithrombotics may represent an independent risk factor for developing chronic constipation. | F Bracci D Badiali P Pezzotti G Scivoletto U Fuoco L Di Lucente A Petrelli E Corazziari | 2007 | World Journal of Gastroenterology2007，13，29： | 15 |
| 2 | 遗传性肥胖与心房颤动的关系显示文摘观察性研究已经确定了体质量指数(body mass index,BMI)与心房颤动之间的关联。然而,从观察性研究中推断因果关系会受到混杂因素、逆因果关系和偏倚的影响。该研究的主要目的是应用BMI的遗传学预测因子评估BMI与心房颤动之间的因果关系。方法:纳入1987-2002年期间在美国、冰岛和荷兰实施的7个前瞻性人群队列研究中基线无心房颤动的欧洲血统个体51 646人, | 刘莉 叶鹏 Chatterjee NA Giulianini F Geelhoed B Lunetta KL Misialek JR Niemeijer MN Rienstra M Rose LM Smith AV Arking DE Ellinor PT Heeringa J Lin H Lubitz SA Soliman EZ Verweij N Alonso A Benjamin EJ Gudnason V Stricker BH van der Harst P Chasman DI Albert CM | 2017 | 中华高血压杂志2017，25，2： | 2 |
| 3 | Effects of whole-body vibration exercise on the endocrine system of healthy men显示文摘 | Di Loreto C Ranchelli A Lucidi P | 2004 | J Endocrinol Invest2004，27，： | 1 |
| 4 | Low plateletalpha2beta1 levels in type I von Willebrand disease correlate withimpaired platelet function in a high shear stress system显示文摘 | Di Paola J Federici A B Mannucci P M | 1999 | Blood1999，93，11： | 1 |
| 5 | Fu- sarium oxysporum: exploring the molecular arsenal of a vascular wilt fungus 显示文摘 | DI PIETRO A MADRID M P CARACUEL Z | 2003 | Mol plant pathol2003，4，5： | 1 |
| 6 | Fixed dose rate gem- citabine infusion as first line treatment for advanced stage carcino- ma of the pancreas and biliary tree显示文摘 | Gelibter A Malaguti P Di Cosimo S | 2005 | Cancer2005，104，6： | 1 |
| 7 | Carboplatin-or cisplatin-based chemotherapy in first-line treatment of small-cell lung cancer:the COCIS meta-analysis of individual patient data显示文摘 | Rossi A Di Maio M Chiodini P | 2012 | J Clin Oncol2012，30，14： | 1 |
| 8 | Fluconazole resistance in Candida albicans:a review of mechanisms显示文摘 | CASALINUOVO I A DI FRANCESCO P Garaci E | 2004 | Eur Rev Med Pharmacol Sci2004，8，2： | 1 |
| 9 | Regulation of human ClC-3 channels by multifunctional Ca2+/calmodulin dependent protein kinase显示文摘 | Huang P Liu J Di A | 2001 | J Biol Chem2001，276，20： | 1 |
| 10 | Intradural spinal clear cell carcinoma causing cauda equina syndrome 显示文摘 | Gaetani P Di Ieva metastasis of renal A Colombo P | 2004 | Acta Neurochir (Wien)2004，146，8： | 1 |
| 11 | Control of the growth of zinc-iron phases in the hot-dip galvanizing process 显示文摘 | CULCASI J D SER P R ELSNER C I DI SARLI A R | 1999 | Surf Coat Technol1999，122，1： | 1 |
| 12 | Carbon monoxide: an unusual drug显示文摘 | Gullotta F di M A Ascenzi P | 2012 | IUBMB Life2012，64，5： | 1 |
| 13 | Bifurcations of dynamical systems with sliding: derivation of normal form mapping显示文摘 | di Bernardo M Kowalczyk P Nordmark A | 2002 | Phys D2002，170，17： | 1 |
| 14 | Electroluminescence of silicon nanocrystals in MOS structures显示文摘 | Franzò G Irrera A Moreira E C Miritello M Iacona F Sanfilippo D Di Stefano G Fallica P G Priolo F | | 0，，： | 1 |
| 15 | Estrogen deficiency increases osteoclastogenesis up-regulating T cells activity : a key mechanism in osteoporosis显示文摘 | D' Amelio P Grimaldi A Di Bella S | 2008 | Bone2008，43，1： | 1 |
| 16 | Tacrolimus ointment in the management of atopic dermatitis显示文摘 | Baldo A Cafiero M Di Caterino P | 2009 | Clin Cosmet Investing Dermatol2009，2，： | 1 |
| 17 | Chemokines and chemokine receptors blockers as new drugs for the treatment of chronic obstructive pulmonary disease显示文摘 | Caramori G Di Stefano A Casolari P | 2013 | Curr Med Chem2013，20，35： | 1 |
| 18 | Cystitis Glanduralis Complicating an Eosinolphilic Cystitis a Case Report显示文摘 | Baldi A Di Marino MP Persichetti P | 2003 | In Vivo2003，17，6： | 1 |
| 19 | The cuttingedge technique for safe osteotomies in craniofacial surgery: the piezosurgery bone scalpel 显示文摘 | Nordera P Spanio di Spilimbergo S Stenico A | 2007 | Plast Reconstr Surg2007，120，7： | 1 |
| 20 | Relationship between texture and corrosion resistance in hot-dip galvanized steel sheets显示文摘 | SERE P R CULCASI J D ELSNER C I DI SARLI A R | 1999 | Surface and Coatings Technology1999，122，6： | 1 |
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