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| 1 | Residual renal function in peritoneal dialysis with failed allograft and minimum immunosuppression显示文摘Immunosuppression(IS) is often withdrawn in patients with end stage renal disease secondary to a failed renal allograft, and this can lead to an accelerated loss of residual renal function(RRF). As maintenance of RRF appears to provide a survival benefit to peritoneal dialysis(PD) patients, it is not clear whether this benefit of maintaining RRF in failed allograft patients returning to PD outweigh the risks of maintaining IS. A 49 year-old Caucasian male developed progressive allograft failure nine years after living-donor renal transplantation. Hemodialysis was initiated via tunneled dialysis catheter(TDC) and IS was gradually withdrawn. Two weeksafter IS withdrawal he developed a febrile illness, which necessitate removal of the TDC and conversion to PD. He was maintained on small dose of tacrolimus(1 mg/d) and prednisone(5 mg/d). Currently(1 year later) he is doing exceedingly well on cycler-assisted PD. Residual urine output ranges between 600-1200 m L/d. Total weekly Kt/V achieved 1.82. RRF remained well preserved in this patient with failed renal allograft with minimal immunosuppressive therapy. This strategy will need further study in well-defined cohorts of PD patients with failed allografts and residual RRF to determine efficacy and safety. | Nadear Elmahi éva Csongrádi Kenneth Kokko Jack R Lewin Jamie Davison Tibor Fülp | 2013 | World Journal of Transplantation2013，3，2： | 5 |
| 2 | Genetic improvement of Trichoderma ability to induce systemic resistance显示文摘The beneficial applications of Trichoderma spp. in agriculture include not only the control of plant pathogens, but also the improvement of plant growth, micronutrient availability, and plant tolerance to abiotic stress. In addition, it has been suggested that these fungi are able to increase plant disease resistance by activating induced systemic resistance (ISR) . The mode of action of these beneficial fungi in the Trichoderma -plant-pathogen interaction are many, complex and not completely understood. Numerous lytic enzymes have been characterized, the encoding genes (ech42 gluc78, nag1 from T. atroviride strain P1) cloned, and their role in biocontrol demonstrated. The corresponding biocontrol-related inducible promoters have been used in a reporter system based on the Aspergillus niger glucose oxidase gene (goxA) to monitor biocontrol activity. Glucose oxidase catalyzes the oxygen-dependent oxidation of D-glucose to D-glucono-1,5-lactone and hydrogen peroxide; this latter compound is known to have an antifungal effect and activate the plant defence cascade, thus increasing resistance to pathogen attack. T. atroviride P1 transformants with various promoters gox were tested as seed coating treatments on bean seeds planted in soil infested with a soilborne fungal pathogen. Successively, the emergent leaves were inoculated with a foliar pathogen to determine the effect of the GOX transformants on biocontrol and resistance to pathogen attack. Inoculations with the P1-GOX transformants not only reduced disease symptoms caused by a soil pathogen, but also the lesions of various foliar pathogens applied far from the Trichoderma colonization, thus activating ISR. A similar approach is being use to genetically improve T. harzianum T22, a rhizosphere competent and commercially marketed strain not transformed yet, by using four different gox gene constructs under the control of constitutive and inducible promoters. Plasmids have been introduced in Trichoderma by protoplasts co-transformation. hygromicin resistant progeny selected, and mitotically stable transformants analysed to confirm the presence of the novel enzyme activity. Progenies are being tested for biocontrol ISR inducing activity. | Ciliento R Woo S L Di Benedetto P Ruocco M Scala F Soriente I Ferraioli S Brunner K Zeilinger S Mach R L Lorito M | 2004 | 浙江大学学报(农业与生命科学版)2004，30，4： | 2 |
| 3 | Molecular mechanisms of acute renal failure following ischemia reperfusion显示文摘 | VRTDYRILRN A M DI - MAGGIO F LEEMREIS J R | 2004 | Int J Artif Organs2004，27，12： | 1 |
| 4 | New simple and rapid method for purification of mesenchy- mal stem cells from the human umbilical cord Wharton jelly显示文摘 | Montanucci P G Basta T Pescara I Pennoni F Di Giovanni and R Calafiore | 2011 | Tis- sue Eng Part A2011，，： | 1 |
| 5 | Prevalence of sarcopenia and its association with osteoporosis in 313 older women following a hip fracture 显示文摘 | Di Monaco M Vallero F Di Monaco R | 2011 | Arch Gerontol Geriatr2011，52，： | 1 |
| 6 | The effect of a levonorgestrel-releasing intrauterine device in the treatment of myoma-related menorrhagia显示文摘 | Mercorio F De Simone R Di Zpiezio Sardo A | 2003 | Contraception2003，67，4： | 1 |
| 7 | A new mesophase of isotactic polypropylene in copolymers of propylene with long branched comonomers 显示文摘 | De Rosa C Auriemma F Di Girolamo R | 2010 | Macromolecules2010，43，20： | 1 |
| 8 | (1) H-MR spectroscopy indicates prominent cerebellar dysfunction in benign adult familial myoclonic epilepsy显示文摘 | Striano P Caranci F Di Benedetto R | 2009 | Epilepsia2009，50，： | 1 |
| 9 | Geological impact of some tailing dams in Sardinia,Italy显示文摘 | Di G F Massoli-Novelli R G | 1992 | Environmental Geology and Water Sciences1992，19，3： | 1 |
| 10 | Time-dependent attractor for the oscillon equation显示文摘 | DI PLINIO F DUANE G S TEMAM R | 2011 | Discrete Contin Dyn Syst2011，29，： | 1 |
| 11 | Needle Artifact Localization in 3T MR Images显示文摘 | Di Maio S P Kacher D F Ellis R E | 2006 | Stud Health Teehnol Inform2006，119，： | 1 |
| 12 | Results of laparoscopic anterior resection for rectal adenocarcinoma:retrospective analysis of 157 cases显示文摘 | Pugliese R Di Lernia S Sansonna F | 2008 | Am J Surg2008，195，2： | 1 |
| 13 | Surgical staging for epithelial ovarian tumors of low malignant potential显示文摘 | Di Re F Paladini D Fontanelli R | 1994 | Int J Gynecol Cancer1994，4，5： | 1 |
| 14 | Antileishmanial activity of three saponins isolated from ivy,alpha-hederin, beta-hederin and hedera-colchiside A (1),as compared with their action on mammalian cells cultured in vitro 显示文摘 | Delmas F Di Giorgio C Elias R et a/ | 2000 | Planta Medica2000，66，： | 1 |
| 15 | Secure vinualization for cloud compu- ting显示文摘 | LOMBARDI F Di PIETRO R | 2010 | Journal of Network and Computer Applications2010，34，4： | 1 |
| 16 | An analysis of the efficiency of Italian cruise terminals 显示文摘 | Di Vaio A Medda F R Trujillo L | 2011 | International Journal of Transport Economies2011，38，1： | 1 |
| 17 | Capecitabine versus bolus fluorouracil plus leucovorin (folinic acid) as adjuvant chemotherapy for patients with Dukes' C colon cancer: economic evaluation in an Italian NHS setting 显示文摘 | Di Costanzo F Ravasio R Sobrero A | 2008 | Clin DrugInvestig2008，28，10： | 1 |
| 18 | Preoperative treatment with interleukin-2 in colorectal carcinoma显示文摘 | Vecchio R Latteri F Di Martino M | 1998 | G Chir1998，19，4： | 1 |
| 19 | Angiogenesis as risk factor for plaque vulnerability显示文摘 | Di Stefano R Feiice F Balbarini A | 2009 | Curr Pharm Des2009，15，10： | 1 |
| 20 | Secure virtualization for cloudcomputing显示文摘 | Lombardi F Di Pietro R | 2011 | Journal of Network and Computer Applications2011，34，4： | 1 |
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