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| 1 | Rilotumumab in combination with epirubicin, cisplatin, and capecitabine as first-line treatment for gastric or oesophagogastric junction adenocarcinoma: an open-label, dose de-escalation phase 1b study and a double-blind, randomised phase 2 study显示文摘 | Timothy Iveson Ross C Donehower Irina Davidenko Sergey Tjulandin Andrzej Deptala Mark Harrison Somanath Nirni Kuntegowdanahalli Lakshmaiah Anne Thomas Yizhou Jiang Min Zhu Rui Tang Abraham Anderson Sarita Dubey Kelly S Oliner Elwyn Loh | 2014 | Lancet Oncology2014，，9： | 3 |
| 2 | NEW TOXOPLASMA GONDII GENOTYPES ISOLATED FROM FREE-RANGE CHICKENS FROM THE FERNANDO DE NORONHA, BRAZIL: UNEXPECTED FINDINGS显示文摘 | Dubey J P Rajendran C Costa D G C Ferreira L R Kwok O C H Qu D Su C Marvulo M F V Alves L C Mota R A Silva J C R | 2010 | The Journal of Parasitology2010，，4： | 2 |
| 3 | Combination immunotherapy with Survivin and luteinizing hormone-releasing hormone fusion protein in murine breast cancer model显示文摘AIM To investigate the therapeutic potential of two recombinant proteins, Survivin and luteinizing hormone-releasing hormone (LHRH) fusion protein [LHRH(6 leu)-LTB] for immunotherapy of breast cancer.METHODS Murine 4 T-1 breast cancer model was used to evaluate the efficacy of recombinant proteins in vivo. Twenty four Balb/c mice were divided into 4 groups of 6 mice each. Recombinant Survivin and LHRH fusion protein, alone or in combination, were administered along with immunomodulator Mycobacterium indicus pranii (MIP) in Balb/c mice. Unimmunized or control group mice were administered with phosphate buffer saline. Each group was then challenged with syngeneic 4 T-1 cells to induce the growth of breast tumor. Tumor growth was monitored to evaluate the efficacy of immune-response in preventing the growth of cancer cells.RESULTS Preventive immunization with 20 μg recombinant Survivin and MIP was effective in suppressing growth of 4 T-1 mouse model of breast cancer (P = 0.04) but 50 μg dose was ineffective in suppressing tumor growth. However, combination of Survivin and LHRH fusion protein was more effective in suppressing tumor growth (P = 0.02) as well as metastasis in vivo in comparison to LHRH fusion protein as vaccine antigen alone.CONCLUSION Recombinant Survivin and MIP suppress tumor growth significantly. Combining LHRH fusion protein with Survivin and MIP enhances tumor suppressive effects marginally which provides evidence for recombinant Survivin and LHRH fusion protein as candidates for translating the combination cancer immunotherapy approaches. | Himani Garg Rohit Singh Hada Jagdish C Gupta G P Talwar Shweta Dubey | 2018 | World Journal of Clinical Oncology2018，9，8： | 2 |
| 4 | Structure of Toxoplasma gondii tachyzoites,bradyzoites and spo- rozoites,and biology and development of tissue cysts 显示文摘 | DUBEY J P LINDSAY S SPEER C A | 1998 | Clin Microbiol Rev1998，11，2： | 1 |
| 5 | Genotyping of Toxoplasma gondii by multilocus PCR-RFLP markers:A high resolution and simple method for identification of parasites显示文摘 | Su C Zhang X Dubey J P | 2006 | Int Jarasitol2006，36，7： | 1 |
| 6 | Newly recognized fatal protozoan disease of dogs显示文摘 | DUBEY J P CARPENTER J L SPEER C A | 1988 | J Am Vet Med Assoc1988，192，9： | 1 |
| 7 | National Seroprevalence of Toxoplasma gondii in pigs显示文摘 | Dubey J P Leighty J C Beal V C | 1991 | J Parasitol1991，77，4： | 1 |
| 8 | Neospora-like encephalomyelitis in a calf: pathology, ultrastrueture, and immuno-reactivity显示文摘 | BARR B C CONRAD P A DUBEY J P | 1991 | J Vet Dia gn Invest1991，3，1： | 1 |
| 9 | Xenooestrogens and phytoestrogend induce the synthesis of leukaemia inhibitory factor by human and bovine oviduct cells显示文摘 | Reinhart K C Dubey R K Keller P J | 1999 | MolHumReprod1999，10，5： | 1 |
| 10 | Redescription of Neospora caninum and its differentiation from related coccidia 显示文摘 | DUBEY J P BARR B C BARTA J R | 2002 | Int J Parasitol2002，32，8： | 1 |
| 11 | ITS-RFLP fingerprinting and molecular marker for detection of Fusarium oxysporum f sp ciceris显示文摘 | Dubey S C Tripathi A Singh S R | 2010 | Folia Microbiol (Praha)2010，55，6： | 1 |
| 12 | Evolution of FLASH, a multi-physics scientific simulation code for high-performance computing 显示文摘 | Dubey A Antypas K Calder A C | 2014 | International Journal of High Performance Computing Applications2014，28，2： | 1 |
| 13 | Newly recognized fatal protozoan disease of dogs显示文摘 | Dubey J P Carpenter J L Speer C A | 1988 | Journal of the American Veterinary Medical Association1988，192，9： | 1 |
| 14 | Ultrastructural differentia- tion of Toxoplasrna gondii schizonts (types B to E) and gamonts in the intestines of cats fed bradyzoites 显示文摘 | SPEER C A DUBEY J P | 2005 | Int J Parasitol2005，35，2： | 1 |
| 15 | Identification of quantitative trait loci controlling acute virulence in Toxoplasma gondii显示文摘 | Su C Howe D K Dubey J P | 2002 | Proc Natl Acad Sci USA2002，99，10： | 1 |
| 16 | Comparative ultrastructure of tachyzoites,bradyzoites,andtissue cysts of Neospora caninum and Toxoplasma gondii显示文摘 | C A Speer J P Dubey M M McAllister | 1999 | Int J Parasitol1999，29，： | 1 |
| 17 | Genetic diversity analysis of Sclerotinia sclerotiorum causing stem rot in chickpea using RAPD, ITS- RFLP, ITS sequencing and mycelial compatibility grouping显示文摘 | Mandal A K Dubey S C | 2012 | World J Microbiol Biotechnol2012，28，4： | 1 |
| 18 | Multicentre trials:a US regulatory perspective显示文摘 | ANELLO C O’NEILL RT DUBEY S | 2005 | Stat Methods Med Res2005，14，3： | 1 |
| 19 | Newly recognized falal protozoan disease of dogs显示文摘 | DUBEY J P CARPENTER J L SPEER C A | 1988 | J Am Vet Med Assoc1988，192，9： | 1 |
| 20 | Prevalence of Toxoplasma gon- dii infection in domestic pigs in the New England States 显示文摘 | Gambel H R Brady R C Dubey J P | 1999 | Vet Parasitol1999，82，2： | 1 |
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