|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Therapeutic options for HER-2 positive breast cancer: Perspectives and future directions显示文摘During the last 15 years we have witnessed an unprecedented expansion in the drugs developed to target human epidermal growth factor receptor-2(HER-2) positive breast cancer. Trastuzumab, pertuzumab, adotrastuzumab emtansine and lapatinib are currently food and drug administration(FDA)-approved for the treatment of breast cancer patients with HER-2 overexpressed. However, given the amount of information gathered from years of uninterrupted clinical research, it is essential to have periodic updates that succinctly recapitulate what we have learnt over these last years and help us to apply that information in our daily practice. This review will pursue that objective. We will summarize the most relevant and updated informationrelated to the state of the art management of HER-2 positive breast cancer in all the clinical scenarios including the adjuvant, neoadjuvant and metastatic settings. But we will also critically appraise that literature in order to highlight some key clinical concepts that should not be overlooked. Lastly, this review will also point out some of the most promising strategies that are currently being tested and may soon become available. | Gonzalo Recondo Jr Enrique Dìaz Canton Màximo de la Vega Martin Greco Gonzalo Recondo Sr Matias E Valsecchi | 2014 | World Journal of Clinical Oncology2014，5，3： | 7 |
| 2 | Advances and new perspectives in the treatment of metastatic colon cancer显示文摘During the last decade we have witnessed an unprec-edented outburst of new treatment approaches for the management of metastatic colon cancer.Anti-angio-genic drugs,epidermal growth factor receptor blockers and multi-kinase inhibitors have all resulted in small but consistent improvement in clinical outcomes.However,this progress has paradoxically leaded us into new chal-lenges.In many cases the clinical development was done in parallel and the lack of head-to-head compari-son evolved into circumstances where several valid new'standards of care'are available.Even though desir-able in essence,the availability of many options as well as different possible combinations frequently leaves the busy clinician in the difficult situation of having to choose between one or the other,sometimes without solid evidence to support each decision.In addition,progress never stops and new agents are continuously tested.For these reason this review will try to summa-rize all the clinical trials that constitute the theoretical framework that support our daily practice but will also procure the reader with rational answers to common clinical dilemmas by critically appraising the current literature.Lastly,we will provide with a compilation of promising new agents that may soon become our next line of defense against this deadly disease. | Gonzalo Recondo Jr Enrique Díaz-Cantón Máximo de la Vega Martin Greco Gonzalo Recondo Sr Matias E Valsecchi | 2014 | World Journal of Gastrointestinal Oncology2014，6，7： | 2 |
| 3 | PGE1 accelerate thrombolysis by tissue plasminogen activator 显示文摘 | Plavin SR Schafer AI | 1989 | Blood1989，73，： | 1 |
| 4 | Support of hepatic regeneration by trophic factors from liver-derived mesenchymal stromal/stem cells显示文摘 | Fouraschen SM Hall SR de Jonge J | 2014 | Methods Mol Biol2014，1213，： | 1 |
| 5 | Glossopharyngeal neuralgia:neurosurgical treatment and differential diagnosis显示文摘 | Teixcira MJ de Siqueira SR Bor-Seng-Shu E | 2008 | Acta Neurochir (Wien)2008，150，5： | 1 |
| 6 | S layer protein A of Lactobacillus acidophilus NCFM regulates immature dendritic cell and T cell functions 显示文摘 | Konstantinov SR Smidt H de Vos WM | 2008 | Proc Natl Acad Sci USA2008，105，19： | 1 |
| 7 | Neurodevelopmental and growth outcomes of extremely low birth weight infants after necrotizing enterocolitis显示文摘 | Hintz SR Kendrick DE Stoll BJ | 2005 | Pediatrics2005，115，3： | 1 |
| 8 | Glossopha- ryngealneuralgia : neurosurgical treatment and differential diagno- sis 显示文摘 | Teixeira MJ de Siqueira SR Bor- Seng - Shu E | 2008 | Acta Neuroehir (Wien)2008，150，5： | 1 |
| 9 | Pancreatic anastomotie failure after panereatieoduodenectomy 显示文摘 | Grobmyer SR Rivadeneira DE Goodman CA | 2000 | Am J Surg2000，180，2： | 1 |
| 10 | Mechanisms of hair gra- ying:incomplete melanocyte stem cell maintenance in the niche 显示文摘 | Nishimura EK Granter SR Fisher DE | 2005 | Science2005，307，5710： | 1 |
| 11 | Malnutrition-induced macrophage apoptosis 显示文摘 | Rivadeneira DE Grobmyer SR Naama HA | 2001 | Surgery2001，129，5： | 1 |
| 12 | Repetitive transcranial magnetic stimulation for levodopainduced dyskinesias in Parkinson's disease 显示文摘 | Filipovic SR Rothwell JC van de Warrenburg BP | 2009 | Mov Disord2009，24，2： | 1 |
| 13 | Towards a Practical and Efficient Process for Software Reuse显示文摘 | DE ALMEIDA ES DE LEMOS SR | 2004 | IEEE Transactions on Software Engineering2004，20，6： | 1 |
| 14 | Incidence and risk factors of the post- thrombotic syndrome 显示文摘 | DE WOLF MA WITTENS CH KAHN SR | 2012 | Phlebology2012，271，： | 1 |
| 15 | Gastric cancer: epidemiology, pathology and treatment 显示文摘 | Alberts SR Cervantes A van de Velde CJ | 2003 | Ann Oncol2003，14，2： | 1 |
| 16 | A novel ETV6-NTRK3 gene fusion in congenital fibrosarcoma显示文摘 | Knezevich SR McFadden DE Tao W | 1998 | Nat Genet1998，18，2： | 1 |
| 17 | Gender differences in neurodevelopmental outcomes among extremely preterm,ex-tremely-low-birth weight infants显示文摘 | Hintz SR Kendrick DE Vohr BR | 2006 | Acta Peadiatrica2006，95，： | 1 |
| 18 | Psychological adaptation in children with idiopathic short stature treated with growth hormone or placebo 显示文摘 | Ross JL Sandberg DE Rose SR | 2004 | J Clin Endocrinol Metab2004，89，10： | 1 |
| 19 | Indications and technique of colon and jejunal imterpositions for esophageal disease显示文摘 | Maish MS De Meester SR | 2005 | Surg Clin N Am2005，85，4： | 1 |
| 20 | Evaluation of gestational weight gain guidelines for women with normal prepregnancy body mass index显示文摘 | De Vader SR Neeley HL Myles TD | | 0，，04： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员