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50篇 您的检索式:作者名="Dena A"
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1Ghrelin attenuates gastrointestinal epithelial damage induced by doxorubicin显示文摘AIM:To examine the influence of ghrelin on the regenerative potential of gastrointestinal(GI)epithelium.METHODS:Damage to GI epithelium was induced in mice by two intravenous injections of doxorubicin(10 and 6 mg/kg).Some of the doxorubicin-treated mice received a continuous subcutaneous infusion of ghrelin(1.25μg/h)for 10 d via implanted mini-osmotic pumps.To label dividing stem cells in the S-phase of the cell cycle,all mice received a single intraperitoneal injection of 5'-bromo-2'-deoxyuridine(BrdU)one hour before sacrifice.The stomach along with the duodenum were then removed and processed for histological examination and immunohistochemistry using anti-BrdU antibody.RESULTS:The results showed dramatic damage to the GI epithelium 3 d after administration of chemotherapy which began to recover by day 10.In ghrelintreated mice,attenuation of GI mucosal damage was evident in the tissues examined postchemotherapy.Immunohistochemical analysis showed an increase in the number of BrdUlabeled cells and an alteration in their distribution along the epithelial lining in response to damage by doxorubicin.In mice treated with both doxorubicin and ghrelin,the number of BrdUlabeled cells was reduced when compared with mice treated with doxorubicin alone.CONCLUSION:The present study suggests that ghrelin enhances the regenerative potential of the GI epithelium in doxorubicintreated mice,at least in part,by modulating cell proliferation.Mohamed A Fahim Hazem Kataya Rkia El-Kharrag Dena AM Amer Basel al-Ramadi Sherif M Karam 2011World Journal of Gastroenterology2011,17,33:3
2Understanding chemical reactions between carbons and NaOH and KOH显示文摘M.A Lillo-Ródenas D Cazorla-Amorós A Linares-Solano 2002Carbon2002,,2:2
3High surface area materials prepared from sewage sludge-based precursors显示文摘Ros A Lillo-Ró denas M A Fuente E 2006Chemosphere2006,17,2:1
4Rosiglitazone increased heart failure but did not differ from metformin plus sulphonylurea for other CV outcomes at interim analysis 显示文摘Mark A Hlatky MD Dena M 2007Evid Based Med2007,12,6:1
5High surface area materials prepared from sewage sludge-based precursors 显示文摘ROS A LILLO-RO' M A DENAS FUENTE E 2006Chemosphere2006,65,:1
6Coumestrol antagonizes neuroendoerine actions of estrogen via the estrogen receptor a 显示文摘Dena A Jacob Jennifer L 2001Experimental Biology and Medicine2001,226,:1
7Behaviour of activated carbons with different pore size distributions and surface oxygen groups for benzene and toluene adsorption at low concentrations显示文摘M A Lillo-Ródenas D Cazorla-Amorós A Linares-Solano 2005Carbon2005,43,:1
8In vitro approaches to assess bioavailability and human gastrointestinal mobilization of food-borne polychlorinated biphenyls (PCBs) 显示文摘Adeola A A Dena W M Angus J B 2008J Environ Sci Heal ( Part B)2008,43,:1
9Understanding chemical reactions between carbons and NaOH and KOH: An insight into the chemical activation mechanism显示文摘LILLO-RóDENAS M A CAZORLA-AMORóS D LINARES-SOLANO A 2003Carbon2003,41,2:1
10Closed-loop sequential signal processing and open-loop batch processing approaches for GNSS re- ceiver design显示文摘Van Graas Soloviev F A Haag M U de Gunawar- dena S 2009IEEE Journal of Selected Topics in Signal Processing2009,3,4:1
11Spherical activated carbons for low concentration toluene adsorption显示文摘ROMERO-ANAYA A J LILLO-RóDENAS M A LINARES-SOLANO A 2010Carbon2010,48,9:1
12Modeling Dynamic Experiments on the Anaerobie Degradation of Molasses Wastewater显示文摘Denae M Miguel A Dunn I J 1988Biotechnology and Bioengineering1988,31,1:1
13Human resource management,manufacturing strategy and firm performance显示文摘YOUNDT M A SNELL S A DENA J W 1996A- cademy of Management Journal1996,39,4:1
14Understanding chemical reactions between carbons and NaOH and KOH显示文摘M.A Lillo-Ródenas D Cazorla-Amorós A Linares-Solano 2002Carbon2002,,2:1
15Understanding chemical reactions between carbons and NaOH and KOH显示文摘Lillo-Ro' denas M A Cazorla-Amoro's D Linares-Solano A 2003Carbon2003,41,:1
16Spherical carbons : Synthesis, characterization and activation processes 显示文摘ROMERO-ANAYA A J OUZZINE M LILLO-RO' DENAS M A 2014Carbon2014,68,:1
17Effects of different carbon materials on MgH2 decomposition显示文摘Lillo-Ro'denas M A Guo Z X Aguey-Zinsou K F 2008Carbon2008,46,1:1
18Wheat Hybridization and Polyploidization Results in Deregulation of Small RNAs显示文摘Kenan-Eichler Michal Leshkowitz Dena Tal Lior Noor Elad Melamed-Bessudo Cathy Feldman Moshe Levy Avraham A 2011Genetics2011,,2:1
19Behavior of activated carbons with different pore size distributions and surface oxygen groups for benzene and toluene adsorption at low concentrations 显示文摘Lillo-Ródenas M A Cazorla-Amorós D Linares-Solano A 2005Carbon2005,43,8:1
20Secondary prevention in thrombotic antiphospholipid syndrome显示文摘Pengo V Denas G Banzato A 2012Lupus2012,21,:1
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