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| 1 | Report of an international workshop to standardize baseline evaluation and response criteria for primary CNS lymphoma.显示文摘 | Abrey LE Batchelor TT Ferreri A J Gospodarowicz M Pulczynski EJ Zucca E Smith JR Korfel A Soussain C DeAngelis LM Neuwelt EA O′Neill BP Thiel E Shenkier T Graus F van den Bent M Seymour JF Poortmans P Armitage JO Cavalli F | 2005 | 中国神经肿瘤杂志2005，3，3： | 53 |
| 2 | Treatment of acute periprosthetic infections with prosthesis retention: Review of current concepts显示文摘Periprosthetic joint infection(PJI) is a devastating complication after total joint arthroplasty, occurring in approximately 1%-2% of all cases. With growing populations and increasing age, PJI will have a growing effect on health care costs. Many risk factors have been identified that increase the risk of developing PJI, including obesity, immune system deficiencies, malignancy, previous surgery of the same joint and longer operating time. Acute PJI occurs either postoperatively(4 wk to 3 mo after initial arthroplasty, depending on the classification system), or via hematogenous spreading after a period in which the prosthesis had functioned properly. Diagnosis and the choice of treatment are the cornerstones to success. Although different definitions for PJI have been used in the past, most are more or less similar and include the presence of a sinus tract, blood infection values, synovial white blood cell count, signs of infection on histopathological analysis and one ormore positive culture results. Debridement, antibiotics and implant retention(DAIR) is the primary treatment for acute PJI, and should be performed as soon as possible after the development of symptoms. Success rates differ, but most studies report success rates of around 60%-80%. Whether single or multiple debridement procedures are more successful remains unclear. The use of local antibiotics in addition to the administration of systemic antibiotic agents is also subject to debate, and its pro's and con's should be carefully considered. Systemic treatment, based on culture results, is of importance for all PJI treatments. Additionally, rifampin should be given in Staphylococcal PJIs, unless all foreign material is removed. The most important factors contributing to treatment failure are longer duration of symptoms, a longer time after initial arthroplasty, the need for more debridement procedures, the retention of exchangeable components, and PJI caused by Staphylococcus(aureus or coagulase negative). If DAIR treatment is unsuccessful, the following treatment option should be based on the patient health status and his or her expectations. For the best functional outcome, one- or two-stage revision should be performed after DAIR failure. In conclusion, DAIR is the obvious choice for treatment of acute PJI, with good success rates in selected patients. | Jesse WP Kuiper Robin Tjeenk Willink Dirk Jan F Moojen Michel PJ van den Bekerom Sascha Colen | 2014 | World Journal of Orthopedics2014，5，5： | 12 |
| 3 | Current concepts in the management of radial head fractures显示文摘Fracture of the radial head is a common injury. Over the last decades, the radial head is increasingly recognized as an important stabilizer of the elbow. In order to maintain stability of the injured elbow, goals of treatment of radial head fractures have become more and more towards restoring function and stability of the elbow. As treatment strategies have changed over the years, with an increasing amount of literature on this subject, the purpose of this article was to provide an overview of current concepts of the management of radial head fractures. | Iza?k F Kodde Laurens Kaas Mark Flipsen Michel PJ van den Bekerom Denise Eygendaal | 2015 | World Journal of Orthopedics2015，6，11： | 9 |
| 4 | Dietary and metabolomic determinants of relapse in ulcerative colitis patients: A pilot prospective cohort study显示文摘AIM To identify demographic, clinical, metabolomic, and lifestyle related predictors of relapse in adult ulcerative colitis(UC) patients.METHODS In this prospective pilot study, UC patients in clinical remission were recruited and followed-up at 12 mo to assess a clinical relapse, or not. At baseline information on demographic and clinical parameters was collected. Serum and urine samples were collected for analysis of metabolomic assays using a combined direct infusion/liquid chromatography tandem mass spectrometry and nuclear magnetic resolution spectroscopy. Stool samples were also collected to measure fecal calprotectin(FCP). Dietary assessment was performed using a validated self-administered food frequency questionnaire. RESULTS Twenty patients were included(mean age: 42.7 ± 14.8 years, females: 55%). Seven patients(35%) experienced a clinical relapse during the follow-up period. While 6 patients(66.7%) with normal body weight developed a clinical relapse, 1 UC patient(9.1%) who was overweight/obese relapsed during the follow-up(P = 0.02). At baseline, poultry intake was significantly higher in patients who were still in remission during follow-up(0.9 oz vs 0.2 oz, P = 0.002). Five patients(71.4%) with FCP > 150 μg/g and 2 patients(15.4%) with normal FCP(≤ 150 μg/g) at baseline relapsed during the follow-up(P = 0.02). Interestingly, baseline urinary and serum metabolomic profiling of UC patients with or without clinical relapse within 12 mo showed a significant difference. The most important metabolites that were responsible for this discrimination were trans-aconitate, cystine and acetamide in urine, and 3-hydroxybutyrate, acetoacetate and acetone in serum. CONCLUSION A combination of baseline dietary intake, fecal calprotectin, and metabolomic factors are associated with risk of UC clinical relapse within 12 mo. | Ammar Hassanzadeh Keshtel iFloris F van den Brand Karen L Madsen Rupasri Mandal Rosica ValchevaKaren I Kroeker Beomsoo Han Rhonda C Bell Janis Cole Thomas Hoevers David S Wishart Richard N Fedorak Levinus A Dieleman | 2017 | World Journal of Gastroenterology2017，23，21： | 9 |
| 5 | Intensive insulin therapy in the critically ill patients显示文摘 | Van den Berghe G Wouters P Weekers F | | 0，，19： | 3 |
| 6 | Effect of a loading dose regimen of three infusions of chimeric monoclonal antibody to tumour necrosis factor alpha (infliximab) in spondyloarthropathy: an open pilot study显示文摘 | van den Bosch F Kruithof E Baeten D | 2000 | Annals of the Rheumatic Disease2000，，： | 2 |
| 7 | A cooperative approach to particle swarm optimization 显示文摘 | Van den Bergh F Engelbrech A P | 2004 | IEEE Trans on Evolutionary Computation2004，8，3： | 1 |
| 8 | Costimulatory blockade in patients with rheumatoid arthritis: a pilot, dose-finding, double-blind, placebo-controlled clinical trial evaluating CTLA-4Ig and LEA29Y eighty-five days after the first infusion显示文摘 | MORELAND LW ALTEN R van den BOSCH F l | 2002 | Arthritis Rheum2002，46，6： | 1 |
| 9 | Early prediction of endocrine therapy effect in advanced breast cancer patients using ^99mTc-depreotide scintigraphy 显示文摘 | VAN DEN BOSSCHE B VAN BELLE S DE WINTER F | 2006 | J Nucl Med2006，47，11： | 1 |
| 10 | Neuroendocrinology of prolonged critical illness: effect of continuous thyrotropin-releasing hormone infusion and its combination with growth hormone-secretagogues显示文摘 | Zegher F Baxter RC | 1998 | J Clin Endocrinol Metab1998，83，： | 1 |
| 11 | eal-time PCR assay for the identification of Thrips palmi显示文摘 | KOX L F F van den BELD H E ZIJLSTRA C | 2005 | Bulletin OEPP/EPPO Bulletin2005，35，： | 1 |
| 12 | Suitability of SRM and CN glasses as neutron fluence monitors in FT dating显示文摘 | Bellemans F De Corte F Van den Haute P | 1993 | Nuclear Tracks and Radiation Measurements1993，21，4： | 1 |
| 13 | Imtemsove omsiion therapy in the critically ill patients显示文摘 | van den Berghc G Wouters P Weekers F | 2001 | N Engl J Med2001，345，： | 1 |
| 14 | Molecular and biological characterization of human monoclonal antibodies bingding to the spike and nucleocapsid proteins of Severe Acute Respiratory Syndrome Coronavirus显示文摘 | Van den Brink E N Meulen J Cox F | 2005 | J Virol2005，79，： | 1 |
| 15 | Crystal structure of heat-labile enterotoxin from Escherichia coli with increased thermostability introduced by an engineered disulfide bond in the A subunit 显示文摘 | Van Den Akker F Feil I K Roach C | 1997 | Protein Science1997，6，： | 1 |
| 16 | Cooperative Learning in Neural Networks Using Particle Swarm Optimizers 显示文摘 | van den Bergh F Engelbrecht A P | 2000 | South Africa Computer Journal2000，，26： | 1 |
| 17 | GC-MS analysis of breath odor compounds in liver patients显示文摘 | Van den Velde S Nevens F Van Hee P | 2008 | J Chromatogr B Analyt Technol Biomed Life Sci2008，875，2： | 1 |
| 18 | A cooperative approach to particle swarm optimization 显示文摘 | van den BERGH F ENGELBRECHT A P | 2004 | IEEE Transactions on Evolution- ary Computation2004，8，3： | 1 |
| 19 | Comparing convention- al gauze therapy to vacuum - assisted closure wound therapy显示文摘 | Moues CM van den Bemd GJ Heule F et 81 | 2007 | J Plast Recons: Aesthet Stag2007，60，： | 1 |
| 20 | Intermediate syndrome in organophosphorus poisoning: a prospective study显示文摘 | De Bleecker J Van den Neucker K Colardyn F | 1993 | Crit Care Med1993，21，11： | 1 |
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