|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 焦炭特性及其在高炉下部的变化过程显示文摘气化、石墨化和溶解是影响焦炭从高炉软熔带至炉缸间行为的三个主要过程。过去几年在一些专题项目中对这些过程进行了研究。简要叙述并讨论了这些过程的相互作用及其与焦炭特性的关系。对焦炭的气化反应进行了实验室测试研究,用以评价高炉条件下焦炭的特性。用高炉条件下的气化测试装置测试了几种焦炭试样,考查的质量指标包括反应性、结构变化和强度等。用实际尺寸的焦炭块对块状焦炭试样的高温行为进行了评估,将不同种类的焦炭试样加热到2 000℃,以鉴别其在高温下的行为。高温下焦炭将发生石墨化,对高温反应后的强度进行了评定,并作了显微观察,发现了一些现象和组织结构的变化。焦炭与液态渣铁相互作用的研究结果对焦炭在高炉下部的行为有了更好的理解。通过试验研究了焦炭抗液态铁水溶解的性能,对入炉前的焦炭和经高温反应的焦炭分别进行了试验。分析讨论了焦炭的抗气化、抗石墨化和抗铁水溶解性能与其结构、化学成分和强度的关系。 | B van der Velden C J Atkinson T Bakker J R H Stuurwold G J Tijhuis 徐万仁 | 2014 | 世界钢铁2014,,2: | 11 |
| 2 | The future of computer-aided sperm analysis显示文摘电脑辅助的精子分析(房屋) 技术为分析精子运动特征或 kinematics 在 1980 年代末被开发并且在启用研究的这个领域是高度成功的。房屋也与大成功被使用了在许多动物种测量象精子集中和进步活动性的比例那样的精液特征,包括在驯养的动物生产实验室和繁殖毒物学的宽申请。然而,为人的临床的精液分析使用房屋的尝试大部分由于精子 clumping 和直到现在,预防了的重背景碎片引起的许多人的精液样品介绍的固有的困难取得了差的成功精确数字图象分析。作者考察二个现代房屋平台(Hamilton Thorne CASA-II 和 Microptic SCA6 ) 的改进能力并且与向使用这种技术估计精子的功能而非简单的描述的特征指导我们的焦点的特别参考考虑他们的现在和将来的应用程序。为为人的精液分析作为一个自动化半的系统验证房屋技术的特定的要求也被提供,与为在根据现代认证标准操作的临床的实验室的实现的柔韧的医药实验室测试期望的测量的精确性和无常的特别参考。 | Sharon T Mortimer Gerhard van der Horst David Mortimer | 2015 | Asian Journal of Andrology2015,17,4: | 8 |
| 3 | COX-2 polymorphisms-765G→C and-1195A→G and colorectal cancer risk显示文摘AIM:To determine the possible modulating effect of the COX-2 polymorphisms,-765G→C and-1195A→G, on the risk of colorectal cancer(CRC)in a Dutch population. METHODS:This case-control study includes 326 patients with CRC and 369 age-and gender-matched controls.Genotypes of the COX-2 polymorphisms -765G→C and-1195A→G were determined by polymerase chain reaction-based restriction fragment length polymorphism.COX-2 genotypes and haplotypes were analyzed and odds ratios with 95%confi- dence intervals were estimated by logistic regression. RESULTS:The-765GG genotype was associated with an increased risk of developing CRC(OR,1.45; 95%CI,1.03-2.04).No significant difference was observed in the genotype distribution of the-1195A→ G polymorphism between patients and controls.The GG/AC haplotype was present significantly less often in patients than in controls(OR 0.44;95%CI,0.22-0.85). When the AC,AG and GG haplotypes were investigated separately,the AC haplotype showed a tendency to be less frequent in patients than in controls(OR(AG/AC)0.78; 95%CI,0.57-1.06). CONCLUSION:The-765GG genotype is associatedwith an increased risk of developing CRC and the GG/ AC haplotype seems to protect against CRC.These findings suggest a modulating role for the COX-2 polymorphisms-765G→C and-1195A→G in the development of CRC in a Dutch population. | Juliёt H Hoff Rene HM te Morsche Hennie MJ Roelofs Elise MJ van der Logt Fokko M Nagengast Wilbert HM Peters | 2009 | World Journal of Gastroenterology2009,15,36: | 6 |
| 4 | 儿童癫痫中的神经元抗体:临床特征和未经免疫治疗的历史队列远期预后显示文摘神经元细胞表面抗体在自身免疫性脑炎的发病中起着明确的作用;早期诊断和治疗的患者预后更好。在不伴脑炎的儿童癫痫中也见神经元抗体阳性的报道。文章旨在评估神经元抗体对儿童癫痫患者远期预后是否有影响。该前瞻性研究患者来自荷兰儿童癫痫研究(Dutch Study of Epilepsy,DSEC)的4个中心,于1988年-1992年期间招募患者(n=178),均未接受免疫治疗。以健康且年龄匹配的骨髓捐赠者作为正常对照(n=112)。所有受试者均使用标准方法,检测血清N-甲基-D-天冬氨酸受体(N-methyl-D-aspartate,NMDAR)、α氨基-3-羟基-5-甲基-4-异恶唑丙酸受体、富含亮氨酸胶质瘤失活1蛋白,接触蛋白相关蛋白2(Contactin associated protein like 2,CASPR2)、contactin-2、谷氨酸脱羧酶和电压门控钾通道(Voltage gated potassium channel,VGKC)-复合物抗体。均未使用脑脊液(Cerebrospinal fluid,CSF)样本检测。并将抗体检测结果与随访15年以上的临床资料进行相关性分析。17例患者(9.5%)神经元抗体检测为阳性,分别为VGKC复合物(n=3),NMDAR(n=7),CASPR2(n=4)和contactin-2(n=3),同时有3名(3/112,2.6%)健康对照者神经元抗体检测为阳性,VGKC复合物(n=1),NMDAR(n=2)(P=0.03)。虽然抗体滴度相对较低(细胞表面抗体≤1:100),但17例阳性样本中有8例(47%)可与活性海马神经元表面结合,提示具有潜在的致病性。在抗体阳性患者中更多见预先存在的认知障碍(9/17vs.33/161,P=0.01)。14例抗体阳性患者接受了规范的抗癫痫药物(AEDs)治疗。其中3例(17%)为耐药性癫痫,但与161例抗体阴性的患者中16例为耐药性癫痫(16人,10%)相比,不存在统计学差异。在6和/或12个月有随访样本的96例患者中,7例之前抗体阳性患者中6例抗体转阴,相反,另有7例患者在随访时第一次出现了抗体阳性。在9.5%的儿童新发癫痫患者中发现低水平的神经元抗体阳性,虽然抗体不一定会持续存在,但在随访中可见神经元抗体由阴性转为阳性,这表明抗体可能是由于神经元的损伤或炎症的继发反应所产生的。此外,由于抗体阳性的儿童癫痫患者对规范AEDs的反应和远期预后与抗体阴性患者没有差异,提示在儿童癫痫中常规进行神经元抗体检测意义不大。抗体阳性组中预先存在的认知障碍的发生率较高,17例患者中7例患者CASPR2和contactin-2抗体阳性,以及17例血清样品中8例与活性海马神经元的结合表明,即使是继发反应,神经元抗体也可能参与到儿童癫痫的共病发生中。 | Sukhvir Wright Ada T Geerts Cornelia Maria Jol-van der Zijde 熊维希 慕洁 | 2017 | 癫痫杂志2017,0,4: | 3 |
| 5 | Bidirectional relation between inflammation and coagulation 显示文摘 | Levi M van der Poll T Bailer HR | 2004 | Circulation2004,109,22: | 1 |
| 6 | Diffusion weighted magnetic resonance imaging in acute 显示文摘 | Van Everdingen K J Van der ground T Kappelle LJ | 2007 | Stroke2007,29,: | 1 |
| 7 | A domain size effect in the magnetic hysteresis of NiZn-ferrites 显示文摘 | Van Der Zagg P J Van Der Valk P J Rekveldt M T | 1996 | Appl Phys Lett1996,69,19: | 1 |
| 8 | Comparative analysis of T-cell receptor gene rearrangements at diagnosis and T-cell acute lymphoblastic leukemia (T-ALL) shows high stability of clonal markers for monitoring of minimal residual disease,and reveals the occurrence of second T-ALl,显示文摘 | Szczepanski T van der Velden VH Raft T Jacobs DC van Wering ER Bruggemann M | 2003 | leukemia2003,17,11: | 1 |
| 9 | Agricultural nutrient losses to surface water in the Netherlands:Impact, strategies, and perspectives显示文摘 | Van Der Molen D T Breeuwsma A Boers P C M | 1998 | Journal of Environmentol Quality1998,27,1: | 1 |
| 10 | A new technique of reversibly adsorbed phosphate显示文摘 | Fokkink L G J Van Reimsdijk W H | 1987 | Soil Sci Soc Am J1987,51,: | 1 |
| 11 | Tamponade of presacral hemorrhage with hemostatic sponges fixed to the sacrum with endoscopic helical rackers:report of two cases显示文摘 | BODEGOM M E RAKIC S | 2004 | Dis Colon Rectum2004,47,9: | 1 |
| 12 | A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma显示文摘 | Van der Bruggen P T raver Sari C Chomez P | 1991 | Science1991,254,5038: | 1 |
| 13 | Effect of dietary keto acid on intermediary metabolism of nutrients in Atlantic salmon (Salmo salar) during 17 betha-estradiol-induced vitellogenin synthesis 显示文摘 | Olin T Junjvid H Von der Decken A | 1992 | Anita Sei1992,42,: | 1 |
| 14 | Studies on pore systems in catalysts: Ⅶ, description of the pore dimensions of carbon blacks by the t methodl显示文摘 | DE BORE J H LINSEN B G VAN DER P T | 1965 | Journal of Catalysis1965,4,: | 1 |
| 15 | Arterial stiffness and risk of cor onary heart disease and stroke: the Rotter-dam Study 显示文摘 | MATTACE RASO F U VAN DER CAMMEN T J HOFMAN A | 2006 | Circulation2006,113,: | 1 |
| 16 | Cardiac death and reinfarction after 1 year in the thrombus aspiration during percutaneous coronary intervention in acute myo- cardial infarction study (TAPAS): a 1-year follow-up study显示文摘 | Vlaar PJ Svilaas T van der Horst IC | 2008 | Lancet2008,371,15: | 1 |
| 17 | Different arbuscular mycorrhizal fungi species are potential determinants of plant community structure显示文摘 | Van der Heijden MGA Boller T Wiemken A Sanders IR | 1998 | Ecology1998,79,: | 1 |
| 18 | The Influence of Crosslinkage on the Distribution Cofficients and Anion Exchange Behavior of Some Elements in Hydrochloric Acid显示文摘 | Van der Walt T N Strelow F W E Verheij R | 1985 | Solvent Extr Ion Exc1985,3,: | 1 |
| 19 | Rationale for restoration of physiological anticoagulant pathways in patients with sepsis and disseminated intravascular coagulation 显示文摘 | Levi M de Jonge E van der Poll T | 2001 | Crit Care Med2001,29,7: | 1 |
| 20 | Anticoagulant therapy for acute lung injury or pneumonia显示文摘 | Sehultz M J Levi M Van der Poll T | 2003 | Curr Drug Targets2003,4,4: | 1 |