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| 1 | Evaluation of in vitro antioxidant and apoptotic activities of Cyperus rotundus显示文摘Objective:To evaluate in vitro antioxidant and apoptotic activities of Crperus rotundas(C.rotundus).Methods:The phytochemical study and the antioxidant activities of both methanol and aqueous extracts from C.rotundus aerial part were determined.In addition,these extracts were also investigated for their cytotoxic and apoptotic activities.The major compound of the methanol extract was isolated.Both metlianol and aqueous extracts(300,150,and 50μg/mL)were evaluated for their antioxidant activity by the xanthine/xanthine oxidase assay system.However,16,8,and 4 mg/mL of each extract were tested to investigate their OH.formation scavenging potential.Aqueous extract(800,400.and 200μg/mL)and melhunol extract(350,175,and 88μg/mL)were tested against lipid peroxidation,induced by 75μM H_2O_2,The cytotoxicity(by MTT assay)and cell DNA fragmentation of both extracts were evaluated Inwards K562 and L1210 cell lines.The major compound was obtained from the butanol fraction of methanol extract and its structure was determined by KMN spectroscopic analysis.Results:The methanol and aqueous extracts showed respectively,88%and 19%inhibition of xanthine oxidase activity.Vet.the same extracts inhibited lipid peroxidation by 61.5%and 42.0%.respectively.Roth extracts inhibited OH.formation by 27.1%and 25.3%,respectively.Only methanol cxtract induced DNA degradation.Orientin was determined as the major compound isolated from the butanol fraction of metlianol extract.Conclusions:It appears that C.rotundus extracts exhibit a potential use as a natural antioxidant and an apoptosis inducer. | Kilani-Jaziri Soumaya Ghedira Zied Nasr Nouha Krifa Mounira Ghedira Kamel Franca Dijoux Marie Genviève Ghedira Chekir Leila | 2014 | Asian Pacific Journal of Tropical Medicine2014，7，2： | 2 |
| 2 | Quercintrin 3'-sulphate from leaves of Leea guinensis显示文摘 | Beck P D D B Dijoux M G Cartier G | 1998 | Phytochemistry1998，47，6： | 1 |
| 3 | Seco-glycosides of oleanolic acid from Beta Vulgaris 显示文摘 | MASSTOT G DIJOUX M G LAVAUD C | 1994 | Phytochemistry1994，37，6： | 1 |
| 4 | Determination of fish origin by using 16S rDNA fingerprinting of bacterial communities by PCR-DGGE: An application on Pangasius fish from Viet Nam显示文摘 | NGUYEN D D L NGOC H H DIJOUX D | 2008 | Food Control2008，19，5： | 1 |
| 5 | A new flavonol glycoside from Catha- ranthus roseus 显示文摘 | Brun G Dijoux M G David B | 1999 | Phytochemistry1999，50，1： | 1 |
| 6 | Nature and thermal stability of paramagnetic defects in natural clay:a study by electron spin resonance 显示文摘 | Bensimon Y Deroide B Dijoux F Martineau M | 2000 | Journal of Physics and Chemistry of Solids2000，61，： | 1 |
| 7 | Determination of fish origin by using 16S rDNA fingerprnting of bacterial communities by PCR-DGGE:an application on Pangasius fish from Viet Nam显示文摘 | le NGUYEN D D NGOC H H DIJOUX D | 2008 | Food Control2008，19，5： | 1 |
| 8 | Quercitrin 3'-sulphate from leaves of Leea guinensis 显示文摘 | Philippe O D Dijoux M G Cartier G | 1998 | Phytochemsitry1998，47，6： | 1 |
| 9 | Antitumor activity anddistribution of pyrroloiniinoquinones in the sponge genus Zyzzva 显示文摘 | Dijoux M G Schnabel P C Hallock Y F | 2005 | Bioorg MeU Chem2005，13，21： | 1 |
| 10 | Abdominal inflammatory myo-fibroblastic tumors in children:report of an appendiceal case andreview of literature 显示文摘 | Bonnet JP Basset T Dijoux D | 1996 | J Pediatr Surg1996，31，9： | 1 |
| 11 | The alert-delay competing risks model for maintenance analysis 显示文摘 | DIJOUX Y GAUDOIN O | 2009 | Journal of Statistical Planning and inference2009，139，5： | 1 |
| 12 | A saponin from leaves of Aphloia madagascariensis显示文摘 | Dijoux MG Lavaud C Massiot G | 1993 | Phytochemistry1993，34，2： | 1 |
| 13 | Quercintrin-3- sulphate from leaves of Leea guinensis 显示文摘 | Beck P Dijoux M G Cartier G | 1998 | Phytochemistry1998，47，6： | 1 |
| 14 | A new flavonol glycoside from Catharanthus roseus 显示文摘 | Brun G Dijoux M G David B | 1999 | Phytochemistry1999，50，1： | 1 |
| 15 | Flavonoids and sesquiterpenes from Tecurium ramosissimum promote antiproliferation of human cancer cells and enhance antioxidant activity: A structure–activity relationship study显示文摘 | Mohamed Ben Sghaier Ines Skandrani Nouha Nasr Marie-Genviève Dijoux Franca Leila Chekir-Ghedira Kamel Ghedira | 2011 | Environmental Toxicology and Pharmacology2011，，3： | 1 |
| 16 | Relationship correlation of antioxidant and antiproliferative capacity of Cyperus rotundus products towards K562 erythroleukemia cells显示文摘 | Soumaya Kilani-Jaziri Aicha Neffati Ilef Limem Jihed Boubaker Ines Skandrani Mohamed Ben Sghair Ines Bouhlel Wissem Bhouri Anne Marie Mariotte Kamel Ghedira Marie-Genviève Dijoux Franca Leila Chekir-Ghedira | 2009 | Chemico-Biological Interactions2009，，1： | 1 |
| 17 | Abdominal Inflammatory myofibrobastic tumors in children: report of an appendiceal case and review of the literalure显示文摘 | Bonnet JP Basset T Dijoux D | 1996 | J Pediatric Surg1996，31，9： | 1 |
| 18 | Graft- ing of ZrO2 powder and ZrOz membrane by fluoroalkyl- silanes显示文摘 | Krajewski S R Kujawski W Dijoux F | 2004 | Colloids Surf A:2004，243，13： | 1 |
| 19 | Determin- ation of fish origin by using 16S rDNA fingerprinting of bacterial communities by PCR-DGGE: An applicati- on on Pangasius fish from Viet Nam 显示文摘 | Lenguyen D D Ngoc H H Dijoux D | 2008 | Food Control2008，19，5： | 1 |
| 20 | Activity-based estimation of human traiectories显示文摘 | Grzonka S Karwath A Dijoux F et aI | 2012 | IEEE Transactions on Robotics2012，28，1： | 1 |
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