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49篇 您的检索式:作者名="Dobrov"
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1Donor-specific cell-free DNA as a biomarker in liver transplantation:A review显示文摘Due to advances in modern medicine,liver transplantation has revolutionised the prognosis of many previously incurable liver diseases.This progress has largely been due to advances in immunosuppressant therapy.However,despite the judicious use of immunosuppression,many liver transplant recipients still experience complications such as rejection,which necessitates diagnosis via invasive liver biopsy.There is a clear need for novel,minimally-invasive tests to optimise immunosuppression and improve patient outcomes.An emerging biomarker in this‘‘precision medicine’‘liver transplantation field is that of donorspecific cell free DNA.In this review,we detail the background and methods of detecting this biomarker,examine its utility in liver transplantation and discuss future research directions that may be most impactful.Tess McClure Su Kah Goh Daniel Cox Vijayaragavan Muralidharan Alexander Dobrovic Adam G Testro 2020World Journal of Transplantation2020,10,11:2
2Pathological response of gastrointestinal stromal tumour to imatinib treatment correlates with tumour KIT mutational status in individual tumour clones 显示文摘Loughrey MB Beshay V Dobrovic A 2006Histopathology2006,49,1:1
3DNA methylation profiling of phyllodes and fibroadenoma tumours of the breast显示文摘Huang KT Dobrovic A Yan M 2010Breast Cancer Res Treat2010,124,2:1
4Methylation-sensitive high resolution melting (MS-HRM):a new approach for sensitive and high-throughput assessment of methylation显示文摘Wojdacz TK Dobrovic A 2007Necleic Acids Res2007,35,6:1
5Variable promoter region CpG island methylation of the putative tumor suppressor gene connexin 26 in breast cancer显示文摘Tan LW Bianco T Dobrovic A 2002Carcinogenesis2002,23,:1
6Methylation-sensitive high-resolution melting 显示文摘Wojdacz TK Dobrovic A Hansen LL 2008Nat Protoc2008,3,12:1
7Methylation of the BRCA1 gene in sporadic breast cancer显示文摘Dobrovic A Simpfendorfer D 1997Cancer Res1997,57,:1
8Methylation-sensitive high resolution melting (MS-HRM): a new approach for sensitive and highthroughput assessment of methylation显示文摘Wojdacz TK Dobrovic A 2007Nucleic Acids Res2007,35,6:1
9Rapid detection of methylation change at H19 in human inrinting disorders using raethylation-sonsitive high-resolution melting显示文摘Wojdacz TK Dobrovic A Algar EM 2008Hum Mutat2008,29,10:1
10Assessing combined methylat ion-sensit ive high resolu t ion me l ting and pyrosequencing for the analysis of heterogeneous DNA methylation显示文摘Candiloro IL Mikeska T Dobrovic A 2011Epigenetics2011,6,4:1
11Methylation sensitive high resolution melting (MS-HRM): a new approach for sensitive and highthroughput assessment of methylation显示文摘WOJDACZ T K DOBROVIC A 2007Nucleic Acids Res2007,35,:1
12Sequence artifacts in DNA from formalin-fixed tissues : causes and strategies for minimization 显示文摘Do H Dobrovic A 2015Clin Chem2015,61,1:1
13A multiplex endpoint RT-PCR assay for quality assessment of RNA ex tracted from formalin-fixed paraffin embedded tissues 显示文摘Takano E A Mikeska T Dobrovic A 2010BMC Biotecnol2010,,10:1
14Prevalence and natural history of ALK positive nonsmall-cell lung cancer and the clinical impact of targeted therapy with ALK inhibitors 显示文摘Chia PL Mitchell P Dobrovic A 2014Clin Epidemiol2014,6,11:1
15Methylation-sensitive high resolution melting (MS-HRM): A new approach for sensitive and high throughput assessment of methylation显示文摘Wojdacz T K Dobrovic A 2007Nucleic Acids Research2007,35,6:1
16DNA methylation in ductal carcinoma in situ of the breast显示文摘Pang JM Dobrovic A Fox SB 2013Breast Cancer Res2013,15,3:1
17Rapid detection of methylation change at H19 in human imprinting disorders using methylation- sensitive high-resolution melting显示文摘] Wojdacz T K Dobrovic A Algar E M 2008Human Mutation2008,29,10:1
18Assessing gene -speeific methylation using HRM - based analysis显示文摘Wong EM Dobrovic A 2011Methods Mol Biol2011,687,:1
19Variable promoter region CpG island methylation of the putative tumor suppressor gene connexin 26 in breast cancer 显示文摘Tan LW Bianco T Dobrovic A 2002Carcinogenesis2002,23,2:1
20Methylation-sensitive high resolution melting (MS-HRM):a new approach for sensitive and high-throughput assessment of methylation显示文摘Wojdacz TK Dobrovic A 2007Nucleic Acids Res2007,35,6:1
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