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| 1 | Vascular endothelial growth factor trap-eye(Aflibercept) for the management of diabetic macular edema显示文摘Diabetic retinopathy(DR)is the most common cause of visual loss among working age individuals.Diabetic macular edema(DME)is an important complication of DR that affects around one third of the patients with DR.Several treatments have been approved for DME ranging from blood pressure and glycemic control to photocoagulation and more recently the use of vascular endothelial growth factor(VEGF)antagonists.The index review discusses aflibercept(EYLEA-Regeneron Pharmaceuticals,Inc.,Tarrytown,New York,NY,and Bayer Healthcare Pharmaceuticals,Berlin,Germany)in the context of other VEGF antagonists currently available for the treatment of DME.A systematic search of literature was conducted on PubMed,Scopus,and Google Scholar with no limitation on language or year of publication.Pre-clinical studies of aflibercept have shown a higher affinity of this molecule for vascular endothelial growth factor A(VEGF-A)along with a longer duration of action as compared to other VEGF antagonists.Recent clinical trials have shown visual outcome results for aflibercept to be similarly favorable as compared to other available agents with the added benefit of fewer required injections and less frequent monitoring.Aflibercept presents a potential exciting new addition to the armamentarium of current VEGF antagonists available for the treatment of DME and other retinal vascular diseases.However,further studies are indicated to confirm the role,safety,and efficacy of aflibercept for DME. | Ahmadreza Moradi Yasir Jamal Sepah Mohammad Ali Sadiq Humzah Nasir Salima Kherani Raafay Sophie Diana V Do Quan Dong Nguyen | 2013 | World Journal of Diabetes2013，4，6： | 8 |
| 2 | Q-switching of waveguide lasers based on graphene/WS_2 van der Waals heterostructure显示文摘We report on the operation of passively Q-switched waveguide lasers at 1 μm wavelength based on a graphene∕WS_2 heterostructure as a saturable absorber(SA). The gain medium is a crystalline Nd:YVO_4 cladding waveguide produced by femtosecond laser writing. The nanosecond waveguide laser operation at 1064 nm has been realized with the maximum average output power of 275 m W and slope efficiency of 37%. In comparison with the systems based on single WS_2 or graphene SA, the lasing Q-switched by a graphene∕WS_2 heterostructure SA possesses advantages of a higher pulse energy and enhanced slope efficiency, indicating the promisingapplications of van der Waals heterostructures for ultrafast photonic devices. | ZIQI LI CHEN CHENG NINGNING DONG CAROLINA ROMERO QINGMING LU JUN WANG JAVIER RODRíGUEZ VáZQUEZ DE ALDANA YANG TAN FENG CHEN | 2017 | Photonics Research2017，5，5： | 7 |
| 3 | How to perform gastrointestinal ultrasound: anatomy and normal findings显示文摘Gastrointestinal ultrasound is a practical, safe, cheap and reproducible diagnostic tool in inflammatorybowel disease gaining global prominence amongst clinicians. Understanding the embryological processes of the intestinal tract assists in the interpretation of abnormal sonographic findings. In general terms, the examination principally comprises interrogation of the colon, mesentery and small intestine using both lowfrequency and high-frequency probes. Interpretation of findings on GIUS includes assessment of bowel wall thickness, symmetry of this thickness, evidence of transmural changes, assessment of vascularity using Doppler imaging and assessment of other specific features including lymph nodes, mesentery and luminal motility. In addition to B-mode imaging, transperineal ultrasonography, elastography and contrast-enhanced ultrasonography are useful adjuncts. This supplement expands upon these features in more depth. | Nathan S S Atkinson Robert V Bryant Yi Dong Christian Maaser Torsten Kucharzik Giovanni Maconi Anil K Asthana Michael Blaivas Adrian Goudie Odd Helge Gilja Dieter Nuernberg Dagmar Schreiber-Dietrich Christoph F Dietrich | 2017 | World Journal of Gastroenterology2017，23，38： | 5 |
| 4 | 非线性时间序列的复杂网络分析显示文摘近十多年,运用复杂网络的方法进行时间序列分析,是非线性动力学发展的最新方向,为传统的以混沌理论为基础的非线性时间序列分析注入了新生力量,在刻画动力系统非线性特征方面,提供了很多崭新的见解,在很多不同领域内都取得了广泛应用.本文回顾三种主要的方法:递归网络、可视图以及转换网络.着重介绍三种网络方法的理论基础和各自的最新进展.本文将指明今后时间序列网络方法的发展方向,并为实际数据分析提供指导作用. | 邹勇 DONNER Reik V MARWAN Norbert DONGES Jonathan F KURTHS Jürgen | 2020 | 中国科学:物理学、力学、天文学2020，50，1： | 3 |
| 5 | Mesenchymal stem cell-based repair of articular cartilage with polyglycolic acid-hydroxyapatite biphasic scaffold显示文摘 | Zhou X Z Leung V Y Dong Q R | 2008 | Int J Artif Organs2008，31，6： | 1 |
| 6 | An overview of passive RFID显示文摘 | CHAWLA V DONGS H | 2007 | Communications Magazine IEEE2007，45，9： | 1 |
| 7 | Acetylcholinesterase inhibitors ameliorate behavioral deficits in the Tg2576 mouse model of Alzheimer' s disease显示文摘 | Dong H Csemansky C A Martin M V | | 0，，： | 1 |
| 8 | Apoptosis: definition, mechanism,and relevance to disease 显示文摘 | Saikumar P Dong Z Mikhailov V | 1999 | Am J Med1999，107，5： | 1 |
| 9 | Electrochemical impedance measurement of prostate cancer cells using carbon nanotube array electrodes in a microfluidic channel 显示文摘 | Yun Y Dong Z Y Shanov V N | 2007 | Nanotechnology2007，18，46： | 1 |
| 10 | Blind multiuser detection: a subspace approach 显示文摘 | WANG Xiao dong POOR H V | 1998 | IEEE Trans Inf Theory1998，44，2： | 1 |
| 11 | Fuse for Power IGBT Converters显示文摘 | Son V Dong Christian Schaeffer Laure-Line Rouve | 1994 | Industry Applications Society Annual Meeting1994，1994，： | 1 |
| 12 | Well-aligned nano-box-beams of SnO,显示文摘 | LlU v DONG H LlU M L | 2004 | Adv Mater2004，16，4： | 1 |
| 13 | 查看详情显示文摘 | Donner R V Heitzig J Donges J E Zou Y Marwan N Kurths J | | 0，，： | 1 |
| 14 | Bayesian-inference-based neural networks for tool wear estimation显示文摘 | Dong Jianfei Subrahmanyam K V R Wong Yoke San | 2006 | The International Journal of Advanced Manufacturing Technology2006，30，910： | 1 |
| 15 | Finite element analysis of electrode wear mechanisms: face extrusion and pitting effects显示文摘 | Dong P Li M V Kimchi M | 1998 | Science Technology of Welding and Joining1998，3，2： | 1 |
| 16 | Reelin and glu-tamic acid decarboxylase67 promoter remodeling in an epigeneticmethionine-induced mouse model of schizophrenia显示文摘 | Dong E Agis-Balboa R C Simonini M V | 2005 | Proc NatlAcad Sci USA2005，102，12： | 1 |
| 17 | Atrial volume reduction following catheter ablation of atrial fibrillation and relation to reduction in pulmonary vein size:an evaluation using magnetic resonance angiography显示文摘 | Jayam V K Dong J Vasamreddy C R | 2005 | J Interv Card Electrophysiol2005，13，2： | 1 |
| 18 | Molecular mapping of a rice gene conditioning thermo-sensitive genic male sterility using AFLP, RFLP and SSR techniques显示文摘 | DONG N V SUBUDHI P K LUONG P N | 2000 | Theor Appl Genet2000，100，： | 1 |
| 19 | Riboflavin induces disease resistance in plants by activating a novel signal transduction pathway显示文摘 | Dong H Beer S V | 2000 | Phytopathology2000，90，8： | 1 |
| 20 | Riboflavin induces disease resistance in plants by activating a novel signal transduction pathway显示文摘 | Dong H Beer S V | 2000 | Phytopathology2000，90，8： | 1 |
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