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| 1 | Predicting lower limb periprosthetic joint infections: A review of risk factors and their classification显示文摘AIM To undertook a systematic review to determine factors that increase a patient's risk of developing lower limb periprosthetic joint infections(PJI).METHODS This systematic review included full-text studies that reviewed risk factors of developing either a hip or knee PJI following a primary arthroplasty published from January 1998 to November 2016. A variety of keywords were used to identify studies through international databases referencing hip arthroplasty, knee arthroplasty, infection, and risk factors. Studies were only included if they included greater than 20 patients in their study cohort, and there was clear documentation of the statistical parameter used; specifically P-value, hazard ratio, relative risk, or/and odds ratio(OR). Furthermore a quality assessment criteria for the individual studies was undertaken to evaluate the presence of record and reporting bias. RESULTS Twenty-seven original studies reviewing risk factors relating to primary total hip and knee arthroplasty infections were included. Four studies(14.8%) reviewed PJI of the hip, 3(11.21%) of the knee, and 20(74.1%) reviewed both joints. Nineteen studies(70.4%) were retrospective and 8(29.6%) prospective. Record bias was identified in the majority of studies(66.7%). The definition of PJI varied amongst the studies but there was a general consensus to define infection by previously validated methods. The most significant risks were the use of preoperative high dose steroids(OR = 21.0, 95%CI: 3.5-127.2, P < 0.001), a BMI above 50(OR = 18.3, P < 0.001), tobacco use(OR = 12.76, 95%CI: 2.47-66.16, P= 0.017), body mass index below 20(OR = 6.00, 95%CI: 1.2-30.9, P = 0.033), diabetes(OR = 5.47, 95%CI: 1.77-16.97, P = 0.003), and coronary artery disease(OR = 5.10, 95%CI: 1.3-19.8, P = 0.017).CONCLUSION We have highlighted the need for the provider to optimise modifiable risk factors, and develop strategies to limit the impact of non-modifiable factors. | David A George Lorenzo Drago Sara Scarponi Enrico Gallazzi Fares S Haddad Carlo L Romano | 2017 | World Journal of Orthopedics2017，8，5： | 3 |
| 2 | Review of Probi-otics Available to Modify Gastrointestinal Flora显示文摘 | GISMONDO M R DRAGO L LOMBARDY A | 1999 | International Journalof Antimicrobial Agents1999，12，： | 1 |
| 3 | ABO genotyping in Italian blood donors显示文摘 | Villa A Drago F Misto R | 1996 | Haematologica1996，81，6： | 1 |
| 4 | Helicobacter pylori in patients with rosacea显示文摘 | Rebora A Drago F Picciotto A | 1994 | Am J Gastroenterol1994，89，： | 1 |
| 5 | Measurement of inflammatory mediators of mast cells and eosinophils in native nasal lavage fluid in nasal polyposis显示文摘 | LORENZO D G DRAGO A PELLITTERI E M | 2001 | Int Arch Allergy Immunol2001，125，2： | 1 |
| 6 | Cortical changes in incipient Alzheimer's disease显示文摘 | Prestia A Drago V Rasser PE | 2010 | J Alzheimers Dis2010，，： | 1 |
| 7 | Comparison of nested PCR and real time PCR of herpes virus infections of central nervous system in HIV patients显示文摘 | Drago L Lombardi A Vecchi ED | 2004 | BMC Infect Dis2004，4，： | 1 |
| 8 | Review of probiotics availa-ble to modify gastrointestinal flora 显示文摘 | GISMONDO M R DRAGO L LOMBARDI A | 1999 | Int J Antimicrob Agents1999，12，4： | 1 |
| 9 | Cortical changes in incipient Alzheimer's disease显示文摘 | Prestia A Drago V Rasser PE | 2010 | J Alzheimers Dis2010，22，4： | 1 |
| 10 | Helicobactor pylori in patients with rosacea 显示文摘 | Drago F Picciotto A | 1994 | Am J Gastroenterol1994，89，9： | 1 |
| 11 | A case of coinfection in a chronic maxillary sinusitis of odontogenic origin: identifica- tion of Dialister pneumosintes显示文摘 | Drago L Vassena C Saibene A M | 2013 | J Endod2013，39，8： | 1 |
| 12 | Comparison of three rapid detection systems for type A influenza virus on tracheal swabs of experimentally and naturally infected birds显示文摘 | Cattoli G Drago A Maniero S | 2004 | Avian Path2004，33，4： | 1 |
| 13 | Real-time PCR assay for rapid detection of Bacillus anthracis spores in clinical samples显示文摘 | DRAGO L LOMBARDI A VECCHI E D | 2002 | Clinical Microbiology2002，40，11： | 1 |
| 14 | Comparison of three rapid detection systems for type A influenza virus on tracheal swabs of experimentally and naturally infected birds 显示文摘 | CATTOLI G DRAGO A MANIERO S | 2004 | Avian Pathol2004，33，： | 1 |
| 15 | Successful treatment of Netherton's syndrome with topical calcipotriol显示文摘 | Godic A Dragos V | 2004 | Eur J Dermatol2004，14，2： | 1 |
| 16 | Long term administration of asucrose rich diet to normal rats:relationshipbetween metabolic and hormonal profiles and morphological changes in the endocrine pancreas显示文摘 | Lombardo YB Drago S Chicco A | 1996 | Metabolism1996，45，： | 1 |
| 17 | Linkage and QTL mapping for Sus scrofa chromosome18显示文摘 | Dragos Wendrich B M Stratil A | 2003 | Animal Breed Genetic2003，120，1： | 1 |
| 18 | Helicobacter pylori in patient with rosacea 显示文摘 | Drago F Picciotto A | 1994 | Am J Gastroenterol1994，，9： | 1 |
| 19 | Sociodemographic and treatment related variables are poor predictors of haloperidol induced motor side effects显示文摘 | Giegling I Drago A Schafer M | | 0，，01： | 1 |
| 20 | Comparison of three rapid detection systems for type A influenza virus on tracheal swabs of experimentally and naturally infected birds显示文摘 | CATTOLI G DRAGO A MANIERO S | 2004 | Avian Pathol2004，33，4： | 1 |
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