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| 1 | Arsenic trioxide promotes mitochondrial DNA mutation and cell apoptosis in primary APL cells and NB4 cell lines显示文摘This study aimed to investigate the effects of arsenic trioxide(As2O3) on the mitochondrial DNA(mtDNA) of acute promyelocytic leukemia(APL) cells.The NB4 cell line was treated with 2.0 μmol/L As2O3 in vitro,and the primary APL cells were treated with 2.0 μmol/L As2O3 in vitro and 0.16 mg kg-1 d-1 As2O3 in vivo.The mitochondrial DNA of all the cells above was amplified by PCR,directly sequenced and analyzed by Sequence Navigatore and Factura software.The apoptosis rates were assayed by flow cytometry.Mitochondrial DNA mutation in the D-loop region was found in NB4 and APL cells before As2O3 use,but the mutation spots were remarkably increased after As2O3 treatment,which was positively correlated to the rates of cellular apoptosis,the correlation coefficient:rNB4-As2O3=0.973818,and rAPL-As2O3=0.934703.The mutation types include transition,transversion,codon insertion or deletion,and the mutation spots in all samples were not constant and regular.It is revealed that As2O3 aggravates mtDNA mutation in the D-loop region of acute promyelocytic leukemia cells both in vitro and in vivo.Mitochondrial DNA might be one of the targets of As2O3 in APL treatment. | MENG Ran1,ZHOU Jin2,SUI Meng3,LI ZhiYong4,FENG GuoSheng1 & YANG BaoFeng2 1 Division of Neurology,the Ninth Clinical Medical College of Beijing University(Shijitan Hospital),Beijing 100038,China 2 The First Hospital of Harbin Medical University,Harbin 150001,China 3 Management Information System,University of International Business and Economics,Beijing 100029,China 4 Department of Radiology,Cambridge University Hospitals NHS Foundation Trust Box 219 Level 5,Addenbrooke’s Hospital Cambridge CB2 0QQ,UK | 2010 | Science China(Life Sciences)2010，53，1： | 10 |
| 2 | 个体网络借贷(P2P)监管立法例及解读显示文摘央行会同其他部委发布的《关于促进互联网金融健康发展的指导意见》明确了'网络借贷业务由银监会负责监管'。十八届五中全会《关于制定国民经济和社会发展第十三个五年规划》要求'规范发展互联网金融'。银监会直面网络借贷(P2P)存在的诸多问题,如何有效地规范发展网络借贷(P2P)活动已经成为亟待解决的问题。规范发展网络借贷(P2P)应以保障投资者合法权益为主轴,以防范其风险发生与传染作为监管措施确立的出发点,以实现普惠金融作为目标,进而促进网络借贷(P2P)的健康持续发展与不断创新。个体网络借贷(P2P)监管立法在体现适度宽松监管政策,坚持适度监管、有效监管、创新监管等原则基础上满足上述要求,从而保障监管立法成为规范监管的善法。 | The Experts’ Suggestion of Rules of Peer to Peer Lending (P2P)Supervision Legislation bythe Expert’s Panel of Central University of Finance and Economics | 2016 | 财经法学2016，，1： | 6 |
| 3 | Typical Survey and Research on Returning-home Migrant Workers' Entrepreneurship in Jiangxi Province under Post-financial Crisis显示文摘In order to study the entrepreneurship situation of Jiangxi return migrant workers after the financial crisis,we have conducted a survey on 107 entrepreneurial return migrant workers in 6 counties of Jiangxi Province.The results show that the return of migrant workers is mainly attributed to personal factors,while social factors are also very important.The major difficulties facing return migrant workers are the funding difficulties,complicated formalities to start a business,difficulty in safeguarding their rights and interests,their own low quality and so on.The support needed by the return migrant workers from the government is manifested in five aspects,say,to improve the service and management for the entrepreneurship of migrant workers,to provide financing policy support,to increase the preferential fiscal and taxation policies,to enhance the entrepreneurship training and to provide preference for the return migrant workers to use land. | OUYANG Zhang-sun1,ZHANG Xin-zhi2,WANG Run-qun3,LUO Feng1,SHEN Ai-guo1,WU Xing-lin1 1.Jiangxi Biotech Vocational College,Nanchang 330299,China 2.The Research Center of the Central China’s Economic Development,Nanchang University,Nanchang 330047,China 3.Jizhou Agricultural Bureau,Jizhou District,Ji’an City in Jiangxi Province,Ji’an 343000,China | 2010 | Asian Agricultural Research2010，2，10： | 2 |
| 4 | Empirical Analysis of the Impact on the Citizenization of Rural Migrant Workers from Urban-rural Dual Institution显示文摘In the article,we attribute the main institutional reasons for impacts on citizenization of migrant workers to the urban-rural dual institution, and analyze its content and the basic characteristics.Then empirical analysis of the impact on the will, the ability,decision-making and process of citizenization of migrant workers is given by use of Logistic regressive model and investigation data.Finally a result is found that although the migrant workers have a strong desire for becoming citizens, the vast majority of migrant workers can not be converted to the public because of their capacity constraints, so as soon as possible to improve their ability of citizenization becomes the key to promote citizenization of migrant workers;furthermore,in the urban-rural dual institution,in addition to the household registration system,the employment system, the social security system,the land system and the education system have obvious obstacles on the will, the ability decision-making and process of citizenization of migrant workers.Therefore,the future focus of innovation of the urban-rural dual institution can not continue to remain in the formal aspects of the household registration system,but as soon as possible to switch to innovation of the employment system,the social security system,the land system and the education system which have a substantial impact on the rights and benefits of rural migrant workers,such as expectations and income. | Huang Kun PhD and Associate Professor,Institute of China’s Economic Reform and Development, Renmin University of China. | 2011 | China Population Today2011，30，5： | 2 |
| 5 | Air bubbles in Water:A Strongly Multiple Scattering Medium for Acoustic Waves显示文摘 | Penciu R S Economou E N | 2000 | Physics Review Letters2000，84，： | 1 |
| 6 | Pigment epithelium-derived fac- tor contributes to insulin resistance in obesity显示文摘 | Crowe S Wu L Economou C | 2009 | Cell metabolism2009，10，1： | 1 |
| 7 | Processing, structure and tribological behaviour of TiC-reinforced plasma sprayed coatings 显示文摘 | Economou S Boute M D Cells J P | 1998 | Wear1998，220，1： | 1 |
| 8 | Patent breadth, of technological progress显示文摘 | O'Donoghue T Scotchmer patent life and the pace Journal of Economics and 7(1):1-32 S Thisse J | 1998 | Management Strategy1998，，： | 1 |
| 9 | Segmentation of color images using multiscale clustering and graph theoretic region synthesis显示文摘 | Makrogiannis S Economou G Fotopoulos S | 2005 | IEEE Transactions on Systems Man and Cybernetics2005，35，2： | 1 |
| 10 | Azalea regeneration fromcallus culture显示文摘 | Economous A S Read P E Spanoudaki M J | 1988 | Acta horticuhurae1988，226，1： | 1 |
| 11 | Processing,structure and tribological behaviour of TiC-reinforced plasma sprayed coatings 显示文摘 | Economous S De Bonte M Celis J E | 1998 | Wear1998，220，： | 1 |
| 12 | Journal of Chromatography A显示文摘 | Economou A Botitsi H Antoniou S Tsipi D | 2009 | 1216 : 58562009，1216，： | 1 |
| 13 | Tribological behaviour at room temperature and at 550 ℃ of TiC-based plasma sprayed coatings in fretting gross slip conditions显示文摘 | Economou S Bonte M De Celis J P | 2000 | Wear2000，244，： | 1 |
| 14 | 显示文摘 | Kafesaki M Penciu R S Economou E N | 2000 | Physics Review Letters2000，84，： | 1 |
| 15 | Elimination of PPV and PNRSV through thermotherapy and meristem-tip culture in neetarine显示文摘 | MANGANARIS G A ECONOMOU A S BOUBOURAKAS I N et at | 2003 | Plant Cell Rep2003，22，： | 1 |
| 16 | Complications of laparoscopic cholecystectomy: anational survey of 4292 hospitals and ananalys is of 77604 cases显示文摘 | DEZ1EL D J MILLIKAN K W ECONOMOU S G | 1993 | Am J Surg1993，165，1： | 1 |
| 17 | Pigment epithelium-derived factor contributes to insulin resistance in obesity显示文摘 | Crowe S Wu LE Economou C | | 0，，1： | 1 |
| 18 | Financing constraints and corporate in investment显示文摘 | of free cash flow corporate American Economic Review Fazzari S Hubbard G Petersen B | 1988 | Brookings Papers on Economic Activity1988，，1： | 1 |
| 19 | Refraction in media with a negative refractive index 显示文摘 | Foteinopoulou S Economou E N Soukoulis C M | 2003 | Phys Rev Lett2003，90，10： | 1 |
| 20 | Classical vibrational modes in phononic lattices:theory and experiment显示文摘 | Sigalas M Kushwaha M S Economou E N | 2005 | Z Kristallogr2005，220，910： | 1 |
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