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| 1 | An integrated approach for increasing breeding efficiency in apple and peach in Europe显示文摘Despite the availability of whole genome sequences of apple and peach,there has been a considerable gap between genomics and breeding.To bridge the gap,the European Union funded the FruitBreedomics project(March 2011 to August 2015)involving 28 research institutes and private companies.Three complementary approaches were pursued:(i)tool and software development,(ii)deciphering genetic control of main horticultural traits taking into account allelic diversity and(iii)developing plant materials,tools and methodologies for breeders.Decisive breakthroughs were made including the making available of ready-to-go DNA diagnostic tests for Marker Assisted Breeding,development of new,dense SNP arrays in apple and peach,new phenotypic methods for some complex traits,software for gene/QTL discovery on breeding germplasm via Pedigree Based Analysis(PBA).This resulted in the discovery of highly predictive molecular markers for traits of horticultural interest via PBA and via Genome Wide Association Studies(GWAS)on several European genebank collections.FruitBreedomics also developed pre-breeding plant materials in which multiple sources of resistance were pyramided and software that can support breeders in their selection activities.Through FruitBreedomics,significant progresses were made in the field of apple and peach breeding,genetics,genomics and bioinformatics of which advantage will be made by breeders,germplasm curators and scientists.A major part of the data collected during the project has been stored in the FruitBreedomics database and has been made available to the public.This review covers the scientific discoveries made in this major endeavour,and perspective in the apple and peach breeding and genomics in Europe and beyond. | Francois Laurens Maria JoséAranzana Pere Arus Daniele Bassi Marco Bink Joan Bonany Andrea Caprera Luca Corelli-Grappadelli Evelyne Costes Charles-Eric Durel Jehan-Baptiste Mauroux Hélène Muranty Nelson Nazzicari Thierry Pascal Andrea Patocchi Andreas Peil Bénédicte Quilot-Turion Laura Rossini Alessandra Stella Michela Troggio Riccardo Velasco Eric van de Weg | 2018 | Horticulture Research2018，5，1： | 10 |
| 2 | Sessile serrated adenomas:Demographic,endoscopic and pathological characteristics显示文摘AIM:To study the demographic and endoscopic characteristics of patients with sessile serrated adenoma(SSA) in a single center.METHODS:Patients with SSA were identified by review of the pathology database of Mayo Clinic Arizona from 2005 to 2007.A retrospective chart review was performed to extract data on demographics,polyp characteristics,presence of synchronous adenomatous polyps or cancer,polypectomy methods,and related complications.RESULTS:One hundred and seventy-one(2.9%) of all patients undergoing colonoscopy had a total of 226 SSAs.The mean(SE) size of the SSAs was 8.1(0.4) mm;42% of SSAs were ≤ 5 mm,and 69% were ≤ 9 mm.Fifty-one per cent of SSAs were located in the cecum or ascending colon.Approximately half of the patients had synchronous polyps of other histological types,including hyperplastic and adenomatous polyps.Synchronous adenocarcinoma was present in seven(4%) cases.Ninety-seven percent of polyps were removed by colonoscopy.CONCLUSION:Among patients with colon polyps,2.9% were found to have SSAs.Most of the SSAs were located in the right side and were safely managed by colonoscopy. | Suryakanth R Gurudu Russell I Heigh Giovanni De Petris Evelyn G Heigh Jonathan A Leighton Shabana F Pasha Isaac B Malagon Ananya Das | 2010 | World Journal of Gastroenterology2010，16，27： | 7 |
| 3 | Importance of mechanisms and processes of the stabilisation of soil organic matter for modelling carbon turnover 显示文摘 | EVELYN S K JEFFREY A B JAN O S | 2003 | Functional Plant Biology2003，30，2： | 1 |
| 4 | PCR detection of human enteric viruses in bathing areas,waste waters and human stools in southwestern France显示文摘 | EVELYNE S FABRICE B VERONIQUE D | 2000 | Research Microbiology2000，151，4： | 1 |
| 5 | Comparison of Three Patent Foramen Ovale Closure Devices in a Randomized Trial (Amplatzer Versus CardioSEAL-STARflex Versus Helex Occluder)显示文摘 | Margaret Taaffe Evelyn Fischer Andreas Baranowski Nicolas Majunke Corinna Heinisch Michaela Leetz Ralph Hein Yves Bayard Franziska Büscheck Madlen Reschke Ilona Hoffmann Nina Wunderlich Neil Wilson Horst Sievert | 2008 | The American Journal of Cardiology2008，，9： | 1 |
| 6 | Mitochondrial localization of a NADR - dependent isocitratedehydrogenase isoenzyme by using the green fluorescent protein as a marker显示文摘 | Susana G Odile R Evelyne B | 1998 | Plant biology1998，，95： | 1 |
| 7 | Seismically induced weter level fluctuation in the Wali well显示文摘 | Liu L B Evelyn Roeloff and Zheng X Y | 1989 | Jourual of Geophysical Research1989，94，7： | 1 |
| 8 | Alamo dam demonstration risk assessment 显示文摘 | Bowles D S Anderson L R Evelyn J B | 2000 | ANCOLD BULLETIN2000，，： | 1 |
| 9 | Formalin-fixed paraffin embedded tissue: the holy grail of clinical proteomics显示文摘 | Valérie B Lise P Evelyne M | 2014 | Proteomics Clinical Application2014，8，10： | 1 |
| 10 | Detection of autoantibodies against oxidized Low-density lipoproteins in patients with coronary artery diease显示文摘 | Agnes B Martial H Evelyne WL | 1995 | Clinical chimica Acta1995，238，： | 1 |
| 11 | 2015, Microbial community structure mediates response of soil C decomposition to litter addition and warming 显示文摘 | COURTNEY A C Alexandre B M Evelyn S K | 2015 | Soil Biology and Biochemistry2015，80，： | 1 |
| 12 | Acrylmide and glycida-mide:genotoxic effects in V79-cells and hμman blood显示文摘 | Matthiaz B Evelyne F Silke F et a1 | | 0，，： | 1 |
| 13 | Proteomic identification of a novel protein regulated in CA1 and CA3 hippocampal regions during intermittent hypoxia显示文摘 | Jon B K David G William M P Visith T Janice A S Leroy R S Shang Z G Jian C Evelyne G | 2003 | Respir Physiol Neurobiol2003，136，： | 1 |
| 14 | Microbial nitrogen turnover in soils under different types of natural forest 显示文摘 | Evelyn H Gert B Sophie Z B | 2004 | Forest Eeology and Management2004，188，： | 1 |
| 15 | Biochemical characterisafi on of the coexisting tyrosinase and laccaso in the soil bacterium Pseudomonas putida F6显示文摘 | Aoife MM Evelyn MD Sarah B | 2007 | Enzyme and Microbial Technology2007，40，5： | 1 |
| 16 | Design and synthesis of new polyphosphorylated upper-rim modifiedcalix arenes as potential and selective chelating agents ofuranyl ion显示文摘 | Evelyne M G Cyrille M Ramon B | 2008 | Tetrahedron2008，65，： | 1 |
| 17 | Vitamin D3 and the immune syst-em:maintaining the balance in health and disease显示文摘 | Femke B Evelyne VE Lut O | 2007 | Nutrition Rese-arch Reviews2007，20，1： | 1 |
| 18 | The multiphasic nature of nonphotochemical quenching:implications for assessment of photosynthetic electron transport based on chlorophyll fluorescence显示文摘 | Richard B Peterson Evelyn A H | 2004 | Photosynthesis Research2004，82，： | 1 |
| 19 | Chlorite dissolution in the acid pH-range: A combined microscopic and macroscopic approach显示文摘 | Felix B Dirk B Evelyn K B | 2003 | Geochimica et Cosmochimica Acta2003，67，8： | 1 |
| 20 | Association of candidemia and retinopathy of prematurity in very low birth weighy infants显示文摘 | Daniel EN Lisa B Evelyn A | 2002 | Ophthalmology2002，109，1： | 1 |
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