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| 1 | 中国妇女妊娠前后单纯服用叶酸对神经管畸形的预防效果显示文摘目的 评价妇女在妊娠前后服用单纯 40 0 μg叶酸增补剂对胎 /婴儿神经管畸形 (NTDs)的预防效果。方法 1993~ 1995年在中国北方的NTDs高发地区和南方的NTDs低发地区妇女增补叶酸的推广项目中 ,共募集从孕前或孕后任何时间开始服药的妇女 130 142名 ,未服药的妇女 1176 89名 ;设计的服药方法从婚检时开始到孕满 3个月为止 ,每天服用单纯叶酸片 40 0 μg ;最后对妇女的分娩结局进行监测并进行预防效果的对比评价研究。结果 服药组妇女生育的胎婴儿中共发现 10 2例NTDs ,对照组胎婴儿中共发现 173例NTDs。末次月经前募集的未服药妇女在孕 2 0周以后分娩的胎婴中NTDs发生率 ,北方为 4 8‰ (16 / 3 318) ,南方为 1 0‰ (2 8/ 2 82 6 5 ) ,而妊娠前后服药妇女组则分别为1 0‰ (13/ 13 0 12 )和 0 6‰ (34/ 5 86 38)。与末次月经前募集的未服药妇女组相比 ,北方服药妇女NTDs发生率明显降低 ,其中依从性大于 80 %的服药组妇女预防率达 85 % (95 %CI为 6 2 %~ 94% ) ,南方地区服叶酸的预防率为 41% (95 %CI为 3 %~ 6 4% )。结论 妇女在妊娠前后每天服用单纯叶酸 40 0 | 李竹 RobertJ Berry 李松 J David Erickson 王红 Cynthia A Moore 赵平 Joseph Mulinare 洪世欣 Lee-Yang C Wong 呼和牧人 Jacqueline Gindler 郝玲 Adolfo Correa 朱慧萍 Elaine Gunter | 2000 | 中华医学杂志2000，80，7： | 185 |
| 2 | Benign epilepsy of childhood with centrotemporal apikea显示文摘 | Elaine C Wirrejl | 2001 | Epilepaia2001，39，： | 1 |
| 3 | Environmental life-cycle assessment of transit buses with alternative fuel technology 显示文摘 | ELAINE C PABLO L | 2012 | Transportation Research Part D: Transport and Ew~ironment2012，17，1： | 1 |
| 4 | Stoma siting~Why and how to mark the abdo- men in preparation for surgery显示文摘 | Elaine C | 2014 | Gastroenterol Nurs2014，12，3： | 1 |
| 5 | Environmental Life-cycle Assessment of Transit Buses with Alternative Fuel Technology显示文摘 | Elaine C M Pablo L D | | 0，，： | 1 |
| 6 | Optimization of Water Supply Operation显示文摘 | Vilas Nitivattananon Elaine C Sadowski Rafael G Qunimpo | 1996 | Water Resources Planning and Management1996，122，5： | 1 |
| 7 | Equiva-lent insulin resistance in latent autoimmune diabetes in adults (LADA) and type 2 diabetic patients显示文摘 | Harvey K Chiu Elaine C Tsai Rattan Juneja | | 0，，2： | 1 |
| 8 | Benign epilepsy of childhood childhood with centrotemporal spike显示文摘 | Elaine C | 1998 | Epilepsia1998，39，4： | 1 |
| 9 | Regulation of ad- iponectin secretion by soy isoflavones has implication for endocrine function of the testis 显示文摘 | Andrew P Manjunatha K N Elaine S C | 2012 | Original Research Article Toxicology Letters2012，209，： | 1 |
| 10 | Contribution of PCB exposure from fish consumption to total dioxin - like dietary exposure显示文摘 | Nancy Judd William C Griffith Elaine M Faustman | 2004 | Regul Toxicol Pharm2004，40，： | 1 |
| 11 | Effect of postharvest processing on texture profile analysis of cooked rice 显示文摘 | Elaine T C Brenda G L Bong K M | 1995 | Crereal Chemistry1995，75，2： | 1 |
| 12 | Lipid profiling identifies a triacylglycerol signature of insulin resistance and improves diabetes prediction in humans显示文摘 | Rhee Eugene P Cheng Susan Larson Martin G Walford Geoffrey A Lewis Gregory D McCabe Elizabeth Yang Elaine Farrell Laurie Fox Caroline S O’Donnell Christopher J Carr Steven A Vasan Ramachandran S Florez Jose C Clish Clary B Wang Thomas J Ger | 2011 | Journal of Clinical Investigation2011，，4： | 1 |
| 13 | Subcutaneous panniculitic T-cell lymphoma is a tumor of cytotoxic T lymphocytes显示文摘 | Shimareet Kumar Lazlo Krenacs Jeffrey Medeiros Kojo S.J Elenitoba-Johnson Timothy C Greiner Lynne Sorbara Douglas W Kingma Mark Raffeld Elaine S Jaffe | 1998 | Human Pathology1998，，4： | 1 |
| 14 | Synthesis and Biological Evaluation of Some 6-Substi?tuted Purines显示文摘 | FERNANDA G B ELAINE S C MAGNUM 0 M | 2007 | EurJ of Med Chern2007，42，： | 1 |
| 15 | Insulin-Like growth factor binding protein-5 is a target of maVix metalloproteinase- 7:implications for epithelial-mesenchymal signaling显示文摘 | Elainers E Duval C McCaiq C | 2005 | Cancer Res2005，65，16： | 1 |
| 16 | Data stream clustering: A survey显示文摘 | JONATHAN A S ELAINE R F~ RODRIGO C B | 2013 | ACM Computing Sur- veys2013，46，1： | 1 |
| 17 | Effect of Cooling and Freezing on the Digestibility of Debranched Rice Starch and Physical Properties of Resulting Material显示文摘 | Harmeet S G Charles J Elaine T C | 2001 | Starch2001，53，： | 1 |
| 18 | Optimization of Water Supply Operation显示文摘 | VUas N Elaine C S Rafael G Q | 1996 | Water Resources Planning and Management1996，122，5： | 1 |
| 19 | Benign epilepsy of childhood with centrotemporal spike 显示文摘 | Elaine C | 1998 | Epilepsia1998，39，4： | 1 |
| 20 | Sexual functioning, psychopathology and quality of life in patients with schizophrenia 显示文摘 | David C Elaine C Leah B | 2007 | Schizophrenia Research2007，94，： | 1 |
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