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| 1 | Natural orifice translumenal endoscopic surgery: Progress in humans since white paper显示文摘Since the first description of the concept of natural orifice translumenal endoscopic surgery (NOTES), a substantial number of clinical NOTES reports have appeared in the literature. This editorial reviews the available human data addressing research questions originally proposed by the white paper, including determining the optimal method of access for NOTES, developing safe methods of lumenal closure, suturing and anastomotic devices, advanced multitasking platforms, addressing the risk of infection, managing complications, addressing challenges with visualization, and training for NOTES procedures. An analysis of the literature reveals that so far transvaginal access and closure appear to be the most feasible techniques for NOTES, with a limited, but growing transgastric, transrectal, and transesophageal NOTES experience in humans. The theoretically increased risk of infection as a result of NOTES procedures has not been substantiated in transvaginal and transgastric procedures so far. Development of suturing and anastomotic devices and advanced platforms for NOTES has progressed slowly, with limited clinical data on their use so far. Data onthe optimal management and incidence of intraoperative complications remain sparse, although possible factors contributing to complications are discussed. Finally, this editorial discusses the likely direction of future NOTES development and its possible role in clinical practice. | Byron F Santos Eric S Hungness | 2011 | World Journal of Gastroenterology2011，17，13： | 13 |
| 2 | Colonoscopic yield of colorectal neoplasia in daily clinical practice显示文摘AIM:To assess the prevalence and location of ad-vanced neoplasia in patients undergoing colonoscopy,and to compare the yield per indication.METHODS:In a multicenter colonoscopy survey (n = 18 hospitals) in the Amsterdam area (Northern Holland),data of all colonoscopies performed during a three month period in 2005 were analyzed. The location and the histological features of all colonic neoplasia were recorded. The prevalence and the distribution ofadvanced colorectal neoplasia and differences in yield between indication clusters were evaluated. Advanced neoplasm was defi ned as adenoma > 10 mm in size,with > 25% villous features or with high-grade dyspla-sia or cancer.RESULTS:A total of 4623 eligible patients underwent a total colonoscopy. The prevalence of advanced neo-plasia was 13%,with 281 (6%) adenocarcinomas and 342 (7%) advanced adenomas. Sixty-seven percent and 33% of advanced neoplasia were located in the distal and proximal colon,respectively. Of all patients with right-sided advanced neoplasia (n = 228),51% had a normal distal colon,whereas 27% had a syn-chronous distal adenoma. Ten percent of all colono-scopies were performed in asymptomatic patients,7% of whom had advanced neoplasia. In the respective procedure indication clusters,the prevalence of right-sided advanced neoplasia ranged from 11%-57%. CONCLUSION:One out of every 7-8 colonoscopies yielded an advanced colorectal neoplasm. Colonoscopy is warranted for the evaluation of both symptomatic and asymptomatic patients. | Jochim S Terhaar sive Droste Mike E Craanen Rene WM van der Hulst Joep F Bartelsman Dick P Bezemer Kim R Cappendijk Gerrit A Meijer Linde M Morsink Pleun Snel Hans ARE Tuynman Roy LJ van Wanrooy Eric IC Wesdorp Chris JJ Mulder | 2009 | World Journal of Gastroenterology2009，15，9： | 6 |
| 3 | Sofosbuvir and ledipasvir fixed-dose combination with and without ribavirin in treatment-naive and previously treated patients with genotype 1 hepatitis C virus infection (LONESTAR): an open-label, randomised, phase 2 trial显示文摘 | Eric Lawitz Fred F Poordad Phillip S Pang Robert H Hyland Xiao Ding Hongmei Mo William T Symonds John G McHutchison Fernando E Membreno | 2013 | The Lancet2013，，： | 5 |
| 4 | A family study of endophenotypes for psychosis within an early intervention programme in Hong Kong: Rationale and preliminary findings显示文摘The study of endophenotypes may be a viable strategy to tackle the genetic complexity and phenotypic heterogeneity of psychosis, but this research direction is relatively under-developed in China as compared to Western countries. We have recently initiated one of the first family studies of endophenotypes for psychosis in China. Patients entering an established early psychosis intervention service are recruited into this research project for phenotyping, endophenotyping and genotyping. At the endophenotypic level, four domains (neurological soft signs, neurocognition of prospective memory, social cognition of facial emotion recognition, and affective cognition of anticipatory and consummatory pleasure) are studied in the sample of patients with psychosis and their unaffected siblings. This article illustrates the benefit of a research-oriented clinical programme and its findings based on the data collected as of early 2011. | LUI Simon S Y SHAM Pak CHAN Raymond C K CHEUNG Eric F C | 2011 | Chinese Science Bulletin2011，56，32： | 2 |
| 5 | Manganese superoxide dismutase expression in endothelial progenitor cells accelerates wound healing in diabetic mice显示文摘 | Marrotte Eric J Chen Dan-Dan Hakim Jeffrey S Chen Alex F | 2010 | Journal of Clinical Investigation2010，，12： | 2 |
| 6 | Nanofabrication with proximal probes显示文摘 | Campbell Paul M Perkins F Keith | 1997 | Proceedings of the IEEE1997，85，4： | 1 |
| 7 | Association between dietary patterns and plasma biomarkers of obesity and cardiovascular disease risk 显示文摘 | TERESA T F ERIC B R DONNA S | 2001 | Am J Clin Nutr2001，73，： | 1 |
| 8 | Uncertainty in estimating carbon emissions from boreal forest fires显示文摘 | Nancy H F F Pierre G Eric S K | 2004 | Journal of Geophysical Research2004，109，： | 1 |
| 9 | in vitro and in vivo evaluation of a melamine dendrimer as avehicle or drug delivery显示文摘 | VOGTLE L MICHAEL F ERIC E S | 2004 | International Journal of Pharmaceu2004，281，12： | 1 |
| 10 | Clinical practice guideline for the use of antimicrobial agents in neutropenic patients with cancer:2010 update by the infectious diseases society of america显示文摘 | Alison G F Eric J B Kent A S | | 0，，04： | 1 |
| 11 | Saline preferendum for the European sea bass, Dicentrarchus labrax, larvae and juveniles: effect of salinity on early development and sex determination 显示文摘 | ERIC S ALEXIS F PIERRICK H | 2003 | Journal of Experimental Marine Biology and Ecology2003，287，1： | 1 |
| 12 | Liver failure after an uncovered TIPS procedure associated with hepatic infarction显示文摘Transjugular intrahepatic portosystemic shunt (TIPS) is a safe and effective procedure for the treatment of complications of liver cirrhosis, such as refractory ascites, hepatic hydrothorax and refractory variceal bleeding. The aim of this paper is to describe a rare case of liver failure after a TIPS procedure. A 38-year-old diabetic male with Child-Pugh C liver cirrhosis due to chronic hepatitis C infection who had developed refractory ascites was scheduled for a TIPS procedure. Within 24 h following TIPS placement, the patient developed distributive shock, jaundice, persistentgrade 3 hepatic encephalopathy, severe coagulopathy andacute renal failure. He was treated with lactulose enemas, broad-spectrum antibiotics and blood-derived products. Laboratory data revealed a 100-fold increase in aminotransferases and a non-enhanced computed tomography showed an irregular hypodense area in the right posterior segment of the liver. Despite being initially being in a stable condition, the patient developed progressive liver failure and died 2 mo later. Hepatic infarction is an uncommon phenomenon after a TIPS procedure; however, it can greatly complicate the course of a disease in a patient with an already compromised liver function. | Eric López-Méndez Daniel Zamora-Valdés Mariana Díaz-Zamudio Oscar F Fernández-Díaz Lourdes ávila | 2010 | World Journal of Hepatology2010，2，4： | 1 |
| 13 | The Balanced Scorecard,competitive strategy,and performance显示文摘 | Eric M O Stanley F S | 2002 | European Jourmal of Operational Research2002，56，： | 1 |
| 14 | A room-temperature molten salt prepared from AuCl3 and 1-ethyl-3-methylimidazolium chloride显示文摘 | Eric R S Jonathan E S Michael F O | 1999 | Inorg Chem1999，38，17： | 1 |
| 15 | The role of visualization incomputer science education显示文摘 | Eric F Monika A Clifford A S | 2012 | Computers in the Schools2012，01，29： | 1 |
| 16 | 1,3-Dithietane显示文摘 | Eric B Eugene R C Paul F S | 1976 | J Am Chem Soc1976，98，： | 1 |
| 17 | Statistical approach to unsupervised defect detection and multiscale localization in two-texture images显示文摘 | ARUNKUMAR G H S ERIC F Hequet | 2008 | Optical Engineering2008，47，2： | 1 |
| 18 | Azides:their preparation and synthetic uses显示文摘 | Eric F V S Kenneth T | 1988 | Chem Rev1988，88，： | 1 |
| 19 | Raped evolution of H5NI influenza viruses in chickens in Hong Kong显示文摘 | Nan N Z Kenned Y F S Eric C J C | 1999 | Virology1999，134，90： | 1 |
| 20 | Methods for Kinetic and Thermodynamic Analysis of Aminoacyl - tRNA Synthetases显示文摘 | CHRISTOPHER S F ERIC A F JOHN J | 2008 | Methods2008，44，2： | 1 |
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