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| 1 | Gastroenteropancreatic neuroendocrine tumours显示文摘 | Irvin M Modlin Kjell Oberg Daniel C Chung Robert T Jensen Wouter W de Herder Rajesh V Thakker Martyn Caplin Gianfranco Delle Fave Greg A Kaltsas Eric P Krenning Steven F Moss Ola Nilsson Guido Rindi Ramon Salazar Philippe Ruszniewski Anders Sundin | 2008 | Lancet Oncology2008,,1: | 8 |
| 2 | High-density SNP-based genetic maps for the parents of an outcrossed and a selfed tetraploid garden rose cross, inferred from admixed progeny using the 68k rose SNP array显示文摘Dense genetic maps create a base for QTL analysis of important traits and future implementation of marker-assisted breeding.In tetraploid rose,the existing linkage maps include<300 markers to cover 28 linkage groups(4 homologous sets of 7 chromosomes).Here we used the 68k WagRhSNP Axiom single-nucleotide polymorphism(SNP)array for rose,in combination with SNP dosage calling at the tetraploid level,to genotype offspring from the garden rose cultivar‘Red New Dawn’.The offspring proved to be not from a single bi-parental cross.In rose breeding,crosses with unintended parents occur regularly.We developed a strategy to separate progeny into putative populations,even while one of the parents was unknown,using principle component analysis on pairwise genetic distances based on sets of selected SNP markers that were homozygous,and therefore uninformative for one parent.One of the inferred populations was consistent with self-fertilization of‘Red New Dawn’.Subsequently,linkage maps were generated for a bi-parental and a self-pollinated population with‘Red New Dawn’as the common maternal parent.The densest map,for the selfed parent,had 1929 SNP markers on 25 linkage groups,covering 1765.5 cM at an average marker distance of 0.9 cM.Synteny with the strawberry(Fragaria vesca)genome was extensive.Rose ICM1 corresponded to F.vesca pseudochromosome 7(Fv7),ICM4 to Fv4,ICM5 to Fv3,ICM6 to Fv2 and ICM7 to Fv5.Rose ICM2 corresponded to parts of F.vesca pseudochromosomes 1 and 6,whereas ICM3 is syntenic to the remainder of Fv6. | Mirjana Vukosavljev Paul Arens Roeland E Voorrips Wendy P C van't Westende G D Esselink Peter M Bourke Peter Cox W Eric van de Weg Richard G F Visser Chris Maliepaard Marinus J M Smulders | 2016 | Horticulture Research2016,3,1: | 6 |
| 3 | Bovine immunoglobulin protein isolates for the nutritional management of enteropathy显示文摘The gastrointestinal tract is responsible for a multitude of digestive and immune functions which depend upon the balanced interaction of the intestinal microbiota, diet, gut barrier function, and mucosal immune response. Disruptions in one or more of these factors can lead to intestinal disorders or enteropathies which are characterized by intestinal inflammation, increased gut permeability, and reduced capacity to absorb nutrients. Enteropathy is frequently associated with human immunodeficiency virus(HIV) infection, inflammatory bowel disease, autoimmune enteropathy, radiation enteritis, and irritable bowel syndrome(IBS), where pathologic changes in the intestinal tract lead to abdominal discomfort, bloating, abnormal bowel function(e.g., diarrhea, urgency, constipation and malabsorption). Unfortunately, effective therapies for the management ofenteropathy and restoring intestinal health are still not available. An accumulating body of preclinical studies has demonstrated that oral administration of plasmaor serum-derived protein concentrates containing high levels of immunoglobulins can improve weight, normalize gut barrier function, and reduce the severity of enteropathy in animal models. Recent studies in humans, using serum-derived bovine immunoglobulin/protein isolate, demonstrate that such protein preparations are safe and improve symptoms, nutritional status, and various biomarkers associated with enteropathy. Benefits have been shown in patients with HIV infection or diarrhea-predominant IBS. This review summarizes preclinical and clinical studies with plasma/serum protein concentrates and describes the effects on host nutrition, intestinal function, and markers of intestinal inflammation. It supports the concept that immunoglobulin-containing protein preparations may offer a new strategy for restoring functional homeostasis in the intestinal tract of patients with enteropathy. | Bryon W Petschow Anthony T Blikslager Eric M Weaver Joy M Campbell Javier Polo Audrey L Shaw Bruce P Burnett Gerald L Klein J Marc Rhoads | 2014 | World Journal of Gastroenterology2014,20,33: | 2 |
| 4 | Phosphorus diagenesis in lake sediments:investigation using fractionation techniques显示文摘 | Michael R P Martin T A Eric L V | 1995 | Mar Freshwater Res1995,46,: | 1 |
| 5 | Natural otolith microstructure patterns reveal precise homingto natal incubation sites by sockeye salmon(oncorhynchus Nerka)显示文摘 | Quinn T P Eric C V Andrew P H | 1999 | Can J Zool1999,77,: | 1 |
| 6 | Managing Stake- holder Interests in E-Government Implementation: Lessons Learned from a Singapore E-Government Pro-ject显示文摘 | Chee-Wee T Shan L P Eric T K L | 2007 | International Journal of Electronic Government Research2007,3,1: | 1 |
| 7 | Atmospheric CO2 enrichment and nutrient additions to planted soil increase mineralization of soil organic matters, but do not alter microbial utilization of plant- and soilC-sources显示文摘 | Eric P Barry T Andrew JM Shona MO Allan S Pete M | 2008 | Soil Biology Biochemistry2008,40,9: | 1 |
| 8 | Mesenchymal stem cells显示文摘 | MINGUEII J J ERICES A CONGE T P | 2001 | Exp Biolrices Med2001,226,: | 1 |
| 9 | Antioxidant and antibacterial properties of green,black,and herbal teas of Camellia sinensis显示文摘 | Eric W C Eu Y S Pei P T | 2011 | Pharmacognosy Research2011,3,4: | 1 |
| 10 | Determination of dissolved organic nitrogen in natural waters using high-temperature catalytic oxidation显示文摘 | E1-Sayed A B Eric P A Alan D T | 2003 | Trends in analytical chemistry2003,22,11: | 1 |
| 11 | The Bordetella bronchiseptica type Ⅲ secretion system inhibits gamma interferon production that is required for efficient antibody-mediated bacterial clearance 显示文摘 | Mylisa R P Eric T H | 2006 | Infection and immunity2006,74,2: | 1 |
| 12 | Gastroenteropancreatic neuroendocrine tumours显示文摘 | Irvin M Modlin Kjell Oberg Daniel C Chung Robert T Jensen Wouter W de Herder Rajesh V Thakker Martyn Caplin Gianfranco Delle Fave Greg A Kaltsas Eric P Krenning Steven F Moss Ola Nilsson Guido Rindi Ramon Salazar Philippe Ruszniewski Anders Sundin | 2008 | Lancet Oncology2008,,1: | 1 |
| 13 | The Bordetel la bronchiseptica type III secretion system inhibits gamma interferon productiont hat is required for efficient antibody mediated bacterial clearance显示文摘 | Eric T H | 2006 | Infection and Immunity2006,74,2: | 1 |
| 14 | Flap thickness accuracy显示文摘 | Kerry D Solomon Eric Donnenfeld Helga P Sandoval Oday Al Sarraf Terrance J Kasper Mike P Holzer Elizabeth H Slate David T Vroman Flap Thickness Study Group | 2004 | Journal of Cataract & Refractive Surgery2004,,5: | 1 |
| 15 | Oligonucleotide probes for RNA -targeted fluorescence in situ hybridization显示文摘 | Adam P Silverman Eric T Kool | 2007 | Adv Clin Chem2007,43,: | 1 |
| 16 | Managing supplier involvement in new product development:a portfolio approach显示文摘 | FINN W ERIC T P | 2000 | European Journal of Purchasing & Supply Management2000,6,: | 1 |
| 17 | Henloch-Schonlein purpu-ra on adults outcome and prognostic factors显示文摘 | Eric T Gary H | 2002 | J Am SocNephro2002,13,: | 1 |
| 18 | Multiple roles for Bordetella lipopolysaccharide molecules during respiratory tract infection 显示文摘 | Eric T H Andrew P Peggy A | 2000 | Infect Immun2000,68,: | 1 |
| 19 | Parallel Tabu Search for Real-Time Vehicle Routing and Dispatching显示文摘 | Michel G Francois G Jean-Yves P Eric T | 1999 | Transportation Science1999,33,: | 1 |
| 20 | Gastroenteropancreatic neuroendocrine tumours显示文摘 | Irvin M Modlin Kjell Oberg Daniel C Chung Robert T Jensen Wouter W de Herder Rajesh V Thakker Martyn Caplin Gianfranco Delle Fave Greg A Kaltsas Eric P Krenning Steven F Moss Ola Nilsson Guido Rindi Ramon Salazar Philippe Ruszniewski Anders Sundin | 2008 | Lancet Oncology2008,,1: | 1 |