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108篇 您的检索式:作者名="Ernestus"
    题名 作者 年代 出处 被引量
1A complete compilation of matrix metalloproteinase expression in human malignant gliomas显示文摘Glioblastomas are characterized by an aggressive local growth pattern, a marked degree of invasiveness and poor prognosis. Tumor invasiveness is facilitated by the increased activity of proteolytic enzymes which are involved in destruction of the extracellular matrix of the surrounding healthy brain tissue. Elevated levels of matrix metalloproteinases(MMPs) were found in glioblastoma(GBM) cell-lines, as well as in GBM biopsies as compared with low-grade astrocytoma(LGA) and normal brain samples, indicating a role in malignant progression. A careful review of the available literature revealed that both the expression and role of several of the 23 human MMP proteins is controversely discussed and for some there are no data available at all. We therefore screened a panel of 15 LGA and 15 GBM biopsy samples for those MMPs for which there is either no, very limited or even contradictory dataavailable. Hence, this is the first complete compilation of the expression pattern of all 23 human MMPs in astrocytic tumors. This study will support a better understanding of the specific expression patterns and interaction of proteolytic enzymes in malignant human glioma and may provide additional starting points for targeted patient therapy.Carsten Hagemann Jelena Anacker Ralf-Ingo Ernestus Giles H Vince 2012World Journal of Clinical Oncology2012,3,5:18
2Frequency and diagnostic patterns of lymphomas in liver biopsies with respect to the WHO classification显示文摘Christoph Loddenkemper Thomas Longerich Michael Hummel Karen Ernestus Ioannis Anagnostopoulos Hans-Peter Dienes Peter Schirmacher Harald Stein 2007Virchows Archiv2007,,5:2
3Chronic subdural hematoma:surgical treatment and outcome in 104 patients 显示文摘Ernestus RI Beldzinski P Lanfermann H 1997Surg Neurol1997,48,3:1
4Chronic subdural hematomasurgical treatment and outcome in 104 patient显示文摘Ernestus RI Beldzinski P Lanfermann H 1997Surg Neurol1997,48,:1
5Histological study of lumbar intervertebral disc herniation in adolescents 显示文摘Lee JY Ernestus RI Schroder R 2000Acta Neurochir (Wien)2000,142,10:1
6Various surgical treat ments of chronic subdural hematoma and outcome in 172 patients: is membraneetomy necessary?显示文摘Lee JY Ebel H Ernestus RI 2004Surg Neurol2004,61,6:1
7Spinal epidural abscess:prognostic factors and comparison of different surgical treatment strategies显示文摘Lohr M Reithmeier T Ernestus RI 2005Acta Neurochir2005,147,2:1
8Various surgical treatment of chronic subdural hematoma and outcome in 172显示文摘Lee JY Ebel H Ernestus RI 2004Patients is membranectomy necessary Surg neurol2004,61,6:1
9Histological study of lumbar intervertebral disc herniation in adolescents显示文摘Lee JY Ernestus RI Schroder R 2000Acta Neurochir2000,142,:1
10Histological study of lumbar intervertebral disc herniation in adolescents显示文摘Lee JY Ernestus RI Schroder R 2000Acta Neurochir(Wien)2000,142,10:1
11Chronic subdural hematoma:Surgical treatment and outcome in 104 patients显示文摘Ernestus RI Beldzinski P Lanfermann H 1997Surg Neurol1997,48,3:1
12Histological study of lumbar intervertebral disc herniation in adolescents显示文摘LEE JY ERNESTUs RI SCHRODER R 2000Actsa Neurochir(Wien)2000,142,10:1
13Various surgical treatments of chronic subdural hematoma and outcome in 172 patients:is membranectomy显示文摘 Ebel H Ernestus RI 2004J Sung Neural2004,61,6:1
14Polyamine Metabolism in Brain Tumors:Diagnostic Relevance of Quantitative Biochemistry显示文摘ERNESTUS RI ROHN G SCHRODER R 2001J Neurol Neurosurg Psychiatry(S0022-3050)2001,71,:1
15Human brain tumours: spectral patterns detected with localized ^1H-MR spectroscopy 显示文摘Kugel H Heindel W Ernestus RI 1992Radiology1992,183,3:1
16Recurrent spreading depolarizations after subarachnoid hemorrhage decreases oxygen availability in human cerebral cortex 显示文摘Bosche B Graf R Ernestus R I 2010Ann Neurol2010,67,:1
17Polyamine metabolism in brain tumours: diagnostic relevance of quantitative biochemistry 显示文摘Ernestus RI Rohn G Schroder R 2001J-Neurol-Neurosurg-Psychiatry2001,71,1:1
18Chronic subdural hematoma:surgical treatment and outcome in 104 patients显示文摘Ernestus RI Beldzinski P Lanfermann H 1997Surg Neurol1997,48,3:1
19Polyamine metabolism in experimental brain tumors of rat显示文摘Ernestus RI Rohn G Hossmann KA 1993JNeurochem1993,60,2:1
20Various surgical treatments of chronic subdural hematoma and outcome in 172 patients:is membranectomy显示文摘Lee JY Ebel H Ernestus RI 2004J Surg Neural2004,61,6:1
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