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| 1 | Effect of prophylactic clip placement following endoscopic mucosal resection of large colorectal lesions on delayed polypectomy bleeding: A meta-analysis显示文摘BACKGROUND The role of prophylactic clipping for the prevention of delayed polypectomy bleeding(DPB) remains unclear and conclusions from prior meta-analyses are limited due to the inclusion of variety of resection techniques and polyp sizes.AIM To conduct a meta-analysis on the effect of clipping on DPB following endoscopic mucosal resection(EMR) of colorectal lesions ≥ 20 mm.METHODS We performed a search of PubMed and the Cochrane library for studies comparing the effect of clipping vs no clipping on DPB following endoscopic resection. The Cochran Q test and I^2 were used to test for heterogeneity. Pooling was conducted using a random-effects model.RESULTS Thirteen studies with a total of 7794 polyps were identified, of which data was available on 1701 cases of EMR of lesions ≥ 20 mm. Prophylactic clipping was associated with a lower rate of DPB(1.4%) when compared to no clipping(5.2%)(pooled OR: 0.24, 95%CI: 0.12-0.50, P < 0.001) following EMR of lesions ≥ 20 mm.There was no significant heterogeneity among the studies(I^2 = 0%, P = 0.67).CONLUSION Prophylactic clipping may reduce DPB following EMR of large colorectal lesions.Future trials are needed to further identify risk factors and stratify high risk cases in order to implement a cost-effective preventive strategy. | Fares Ayoub Donevan R Westerveld Justin J Forde Christopher E Forsmark Peter V Draganov Dennis Yang | 2019 | World Journal of Gastroenterology2019，25，18： | 9 |
| 2 | 抑郁症的非药物治疗:系统性综述与证据图显示文摘背景抑郁症非药物治疗的疗效比较目前仍然不清楚。方法我们对一些系统性综述作了概述,回顾了随机对照试验(RCT),比较抑郁症非药物治疗的有效性和认知行为治疗(CBT)。对多个电子数据库在2016年2月之前发表的所有文献进行了检索,不限制语言。成对的评阅人进行资料纳入、数据提炼并评估偏倚的风险。在适用的时候进行了荟萃分析。结果我们收录了367项RCT,纳入了约2000名患者,进行了11种治疗,导出17项独立的头对头比较。通过标准化的量表评估,发现CBT、自然疗法、行为干预与躯体活动干预可以降低抑郁的严重程度。然而,这些非药物干预的相对疗效仍然缺乏。这些干预对临床缓解和复发的效果不清楚。CBT的发生率比抗抑郁药物更低。局限性由于证据缺乏一致性、证据不清或偏倚风险高,导致证据的质量只是低到中等,限制了我们研究结果的可信度。结论抑郁症的非药物治疗能减少抑郁症状,在轻度到重度抑郁症患者中,应当合并抗抑郁药物治疗,一同进行。对于非药物治疗的选择,应当根据患者的价值观、偏好、临床和社会因素来与患者共同作出决定。 | Wigdan H Farah Mouaz Alsawas Maria Mainou Fares Alahdab Magdoleen H Farah Ahmed T Ahmed Essa A Mohamed Jehad Almasri Michael R Gionfriddo Ana Castaneda-Guarderas Khaled Mohammed Zhen Wang Noor Asi Craig N Sawchuk Mark D Williams Larry J Prokop M Hassan Murad Annie LeBlanc | 2017 | 英国医学杂志中文版2017，20，11： | 2 |
| 3 | Singlet oxygen inhibits agonist-induced P-selectin expression and formation of platelet aggregates显示文摘 | Stief TW Jeske WP Walenga J Schultz C Kretschmer V Fareed J | 2001 | Clin Appl Thromb Hemost2001，7，3： | 1 |
| 4 | Prevention of venous thromboembolism : international consensus statement 显示文摘 | Nicottish A Breddin H Fareed J | 2002 | J Vasc Bras2002，1，： | 1 |
| 5 | Prevention of venous thromboembolism: international consensus statement: guidelines compiled in accordance with the scientific evidence 显示文摘 | Nicolaides AN Breddin HK Fareed J | 2001 | lnt Angiol2001，20，1： | 1 |
| 6 | pharmacology Of low molecular weight heparins 显示文摘 | Fareed J Hoppensteadt DA | 2003 | Semin Thromb Hemest2003，，： | 1 |
| 7 | Thrombogenic potential of nonionic contrast media? 显示文摘 | FAREED J WALENGA J M SARAVIA G E | 1990 | Radiology1990，174，2： | 1 |
| 8 | Phammcology of the Low molecular weight heparins显示文摘 | Fareed J Hoppeusteadt DA | 1996 | Semin Thromb Hemost1996，22，2： | 1 |
| 9 | Environmental production functions and environmental directional distance functions 显示文摘 | Fare R Grosskopf S Pasurka J C A | 2007 | Energy2007，32，7： | 1 |
| 10 | An update on heparins at the beginning of the new millennium 显示文摘 | Fareed J Hoppensteadt DA Bick RL | 2000 | Semin Thromb Hemost2000，261，： | 1 |
| 11 | Current trends in antithrombotic drug and device development显示文摘 | FAREED J | 1996 | Semin Thromb Hemost1996，22，1： | 1 |
| 12 | Useful laboratory tests for studying thrombogenesis in acute cardiac syndromes显示文摘 | Hoppensteadt DA Laya F | 1998 | Clin Chem1998，44，2： | 1 |
| 13 | Single-port transvesical enucleation of the pros tate:a clinical report of 34 cases显示文摘 | Desai M M Fareed K Berger A K Astigueta J C Irwin B H Aron M | 2010 | BJU Int2010，10，51： | 1 |
| 14 | Pharmacology of loco moleculag weight heparins显示文摘 | Fareed J Hoppensteadt DA | 1996 | Senum Thromb Hemost1996，22，2： | 1 |
| 15 | Pharmacology of the lowmolecular-weight heparins显示文摘 | Fareed J Hoppensteadt DA | 1996 | Semin Thromb Hemost1996，22，2： | 1 |
| 16 | The Relative Efficiency of Illinois Electric Utilities显示文摘 | Fare R Grosskopf S Logan J | | 0，，04： | 1 |
| 17 | In vitro studies on the biochemistry pharmacology of low molecular weight heparins显示文摘 | Jeske W Fareed J | 1999 | Semin Thromb Hemost1999，25，3： | 1 |
| 18 | The relative efficiency of Illi-nois electric utilities 显示文摘 | FARE R GROSSKOPF S LOGAN J | 1983 | Resources and Energy1983，5，4： | 1 |
| 19 | Prevention and treatment of venous thromboembolism-International consensus Statement 显示文摘 | Nicolaides AN Fareed J Kakkar AK | 2013 | Int Angiol2013，32，2： | 1 |
| 20 | Prevention of venous thromboembolism显示文摘 | Breddin HK Fareed J | 2001 | Inter Angiol2001，20，： | 1 |
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