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| 1 | Liver regeneration biology:Implications for liver tumour therapies显示文摘The liver has remarkable regenerative potential,with the capacity to regenerate after 75%hepatectomy in humans and up to 90%hepatectomy in some rodent models,enabling it to meet the challenge of diverse injury types,including physical trauma,infection,inflammatory processes,direct toxicity,and immunological insults.Current understanding of liver regeneration is based largely on animal research,historically in large animals,and more recently in rodents and zebrafish,which provide powerful genetic manipulation experimental tools.Whilst immensely valuable,these models have limitations in extrapolation to the human situation.In vitro models have evolved from 2-dimensional culture to complex 3 dimensional organoids,but also have shortcomings in replicating the complex hepatic micro-anatomical and physiological milieu.The process of liver regeneration is only partially understood and characterized by layers of complexity.Liver regeneration is triggered and controlled by a multitude of mitogens acting in autocrine,paracrine,and endocrine ways,with much redundancy and cross-talk between biochemical pathways.The regenerative response is variable,involving both hypertrophy and true proliferative hyperplasia,which is itself variable,including both cellular phenotypic fidelity and cellular trans-differentiation,according to the type of injury.Complex interactions occur between parenchymal and non-parenchymal cells,and regeneration is affected by the status of the liver parenchyma,with differences between healthy and diseased liver.Finally,the process of termination of liver regeneration is even less well understood than its triggers.The complexity of liver regeneration biology combined with limited understanding has restricted specific clinical interventions to enhance liver regeneration.Moreover,manipulating the fundamental biochemical pathways involved would require cautious assessment,for fear of unintended consequences.Nevertheless,current knowledge provides guiding principles for strategies to optimise liver regeneration potential. | Christopher Hadjittofi Michael Feretis Jack Martin Simon Harper Emmanuel Huguet | 2021 | World Journal of Clinical Oncology2021，12，12： | 2 |
| 2 | Histoacryl plus sclerotherapy versus sclerotherapy alone in the threatment of bleeding esophageal varices:a randomized prospective study显示文摘 | Feretis C Dimopoulus C Benakis P | 1995 | End oscopy1995，27，5： | 1 |
| 3 | Laparoscopic Transcystic Papillotomy under Endoscopic Control for Bile Duct Stones显示文摘 | C. Feretis B. Kalliakmanis P. Benakis N. Apostolidis | 1994 | Endoscopy1994，，08： | 1 |
| 4 | Endoscopic hemostasis of esophageal and gastric variceal bleeding with histoacryl 显示文摘 | Feretis C Tabakopulos D Benakis P | 1990 | Endoscopy1990，22，： | 1 |
| 5 | Endoscopic implantation of Plexiglas (PMMA) microspheresfor the treatment of GERD显示文摘 | FERETIS C BENAKIS P DIMOPOULOS C | 2001 | Gastrointest Endosc2001，53，4： | 1 |
| 6 | Excessive sinle lateral rectus muscle recession in the treament of pediatrie显示文摘 | Feretis D | 1990 | ophthalmology and strabismus1990，27，6： | 1 |
| 7 | Plexiglas ( polymeth- ylmethacrylate) implantation: technique, pre-clinical and clini- cal experience 显示文摘 | Feretis C Benakis P Dimopoulos C | 2003 | Gastrointest Enclose Clin N Am2003，13，1： | 1 |
| 8 | Postoperative external and internal biliary fistulas, unassociated with distal bile duct obstruc- tion: endoscopic traatment显示文摘 | Feretis C Kekis B Bliouras N | 1990 | Endoscopy1990，22，： | 1 |
| 9 | Secondary management and outcome of massive suprachoroidal hemorrhage显示文摘 | Feretis E Mourtzoukos S Mangouritsas G | 2006 | Eur J Ophthalmol2006，16，： | 1 |
| 10 | N-butyl 2-cyanoacrylate (Histoacryl) plus sclerotherapy versus sclerotheragy alone in the treatment of bleeding esophageal varices: a randomized prospective study显示文摘 | Feretis C Dimopoulos C Benakis P | 1995 | Endoscopy1995，27，： | 1 |
| 11 | Vitrectomy and fluid/silicone oil exchange for giant retinal tears 显示文摘 | Leaver P K Cooling R J Feretis E B | 1984 | Br J Ophthalmol1984，68，： | 1 |
| 12 | Plexiglas ( polymethyhnethacrylate ) implantation : technique, pre-clinical studies显示文摘 | Feretis C Benakis P Dimopoulos C | 2003 | Gastrointest Endosc Clin N Am2003，13，1： | 1 |
| 13 | Comparison of external and endonasal dacryocystorhinostomy显示文摘 | Feretis M Newton JR Ram B | 2009 | J Laryngol Otol2009，123，： | 1 |
| 14 | Plexiglas ( polynmethylmethacrylate) implantation : technique, pre-clinical studies 显示文摘 | Feretis C Benakis P Dimopoulos C | 2003 | Gastrointest Endosc Clin N Am2003，13，1： | 1 |
| 15 | Long term consequences of bacteriaicolonization of the biliary tract 'after chole-dochostomy显示文摘 | FERETIS C B CONTOU C T MANOURAS A J | 1984 | Surg Gynecol Obstet1984，159，4： | 1 |
| 16 | Palliation of malignant gastric outlet obstruction with self-expanding metal stents 显示文摘 | Feretis C Benakis P Dimopoulos C | 1996 | Endoscopy1996，28，2： | 1 |
| 17 | Plexiglas (polymetyhl-methacrylate ) impkanttation: technique, pte-clinical studies显示文摘 | Feretis C Benakis P Dimopoulos C | 2003 | Gastrointest Endosc Clin North Am2003，13，1： | 1 |
| 18 | Medium-term resultswith Sacral Nerve Stimulation for management of faecalincontinence, a single centre experience 显示文摘 | Feretis M Karandikar S Chapman M | 2013 | J IntervGastroenterol2013，3，： | 1 |
| 19 | Histoacryl plus sclerotherapy versus sclerotherapy alone in the threatment of bleeding esophageal var- ices : a randomized prospective study 显示文摘 | Feretis C Dimopoulus C Benakis P | 1995 | Endoscopy1995，27，5： | 1 |
| 20 | Comparison of external and endonasal dacryocystorhinostomy 显示文摘 | Feretis M Newton JR Ram B | 2009 | J Laryngol Otol2009，123，3： | 1 |
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