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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Plugging into Enzymes:Nanowiring of Redox Enzymes by a Gold Nanoparticle显示文摘 | Xiao Y Fernando P Eugenii K James F | 2003 | Science2003，299，5614： | 1 |
| 3 | In-situ cure moni-toring of epoxy resins using optical fiber sensors 显示文摘 | Crosby P A Powell G R Fernando G F | 1996 | Smart Materials and Structures1996，5，4： | 1 |
| 4 | Supported metallocene on mesoporous materials显示文摘 | Fernando S Cristiane F P Dirce P | 2007 | Applied catalysis A: General2007，333，1： | 1 |
| 5 | In-situ cure monitoring of epoxy resins using optical fiber sensors显示文摘 | Crosby P A Powell G R Fernando G F | 1996 | Smart Materials and Structures1996，5，4： | 1 |
| 6 | Soil microbial indicators sensitive to land use conversion from pasrures to commercial Eucalyptus grandis plantations in Uruguay显示文摘 | Margarita S Fernando G P Lillian F | 2004 | Applied Soil Ecology2004，，3： | 1 |
| 7 | Dehydrated halloysite intercalated mechanochemically with urea: thermal behavior and structural aspects 显示文摘 | Keller P N Cristiane R B F Fernando W | 2009 | Journal of Colloid and Interface Science2009，338，： | 1 |
| 8 | Soil microbial indicators sensitive to land use conversion from pastures to commercial Eucalyptus grandis plantations in Uruguay显示文摘 | Margarita S Fernando G P Lillian F | 2004 | Applied Soil Ecology2004，，3： | 1 |
| 9 | Conversion of glycerol to hydrogen via asteam reforming process over nickel catalysts显示文摘 | ADHIKARI S FERNANDO S D TO S D F BRICKA R M STEELE P H HARYANTO A | 2008 | Energy Fuels2008，22，2： | 1 |
| 10 | Soilmicrobial indicators sensitive to land use conversion from pastures to commercial Eucalyptus grand is plantations in Uruguay显示文摘 | Margarita S Fernando G P Lillian F | 2004 | Applied Soil Ecology2004，3，： | 1 |
| 11 | Performance analysis of existing and new methods for data hiding with known-host information in additive channels显示文摘 | Fernando P G Balado F Juan R H | 2003 | IEEE Transactions on Signal Processing2003，51，4： | 1 |
| 12 | Temporal and spatial expression of CCN genes in zebrafish 显示文摘 | FERNANDO C A CONRAD P A BARTELS C F | 2010 | Developmental Dynamics2010，239，6： | 1 |
| 13 | Thermal properties of uncross-linked and cross-linked LL- DPE/wax blends 显示文摘 | MARABELLA F M WESTPHAL S P FERNANDO P L | 2000 | Polym Degrad Stab2000，70，1： | 1 |
| 14 | Temporal and spatial expression of CCN genes in zebrafish显示文摘 | Fernando C A Conrad P A Bartels C F | 2010 | Developmental Dynamics2010，，239： | 1 |
| 15 | The construction of confidence intervals for frequency analysis using resampling techniques显示文摘 | Hall M J van den Boogaard H F P Fernando R C Mynett A E | 2004 | Hydrology and Earth System Sciences2004，8，2： | 1 |
| 16 | Soil microbial indica- tors sensitive to land use conversion from pastures to com- mercial Eucalyptus grand is plantations in Uruguay显示文摘 | Margarita S Fernando G P L illian F | 2004 | Ap- plied Soil Ecology2004，3，： | 1 |
| 17 | First GOCE gravity field models derived by three different approaches显示文摘 | Roland P Sean B Federica M Christoph F Helmut G Wolf D S Eduand H Mirko R Jan M B Oleg A Mantin V Thomas F Reinhard M Ina K Fernando S and Carl C T | | 0，，11： | 1 |
| 18 | A thermodynamic analysis of hydrogen production by steam reforming of glycerol显示文摘 | ADHIKARI S FERNANDO S GWALTNEY S R TO S D F BRICKA R M STEELE P H HARYANTO A | 2007 | Int J Hydrogen Energy2007，32，14： | 1 |
| 19 | Terlipressin and Albumin vs Albumin in Patients With Cirrhosis and Hepatorenal Syndrome: A Randomized Study显示文摘 | Marta Martín–Llahí Marie–No?lle Pépin Mónica Guevara Fernando Díaz Aldo Torre Alberto Monescillo Germán Soriano Carlos Terra Emilio Fábrega Vicente Arroyo Juan Rodés Pere Ginès | 2008 | Gastroenterology2008，，5： | 1 |
| 20 | Thermal Actions for Concrete Bridge Design显示文摘 | BRANCO F A FERNANDO A MENDES P A | 1993 | Journal of Structural Engineering1993，119，8： | 1 |
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