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242篇 您的检索式:作者名="Fontain P"
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1Endoscopic ultrasound staging for early esophageal cancer: Are we denying patients neoadjuvant chemo-radiation?显示文摘AIM To evaluate the accuracy of endoscopic ultrasound(EUS) in early esophageal cancer(EC) performed in a highvolume tertiary cancer center. METHODS A retrospective review of patients undergoing esophagectomy was performed and patients with c T1 N0 and c T2 N0 esophageal cancer by EUS were evaluated. Patient demographics, tumor characteristics, and treatment were reviewed. EUS staging was compared to surgical pathology to determine accuracy of EUS. Descriptive statistics was used to describe the cohort. Student's t test and Fisher's exact test or χ~2 test was used to compare variables. Logistic regression analysis was used to determine if clinical variables such as tumor location and tumor histology were associated with EUS accuracy.RESULTS Between 2000 and 2015, 139 patients with clinical stage Ⅰ or Ⅱ?A esophageal cancer undergoing esophagectomy were identified. There were 25(18%) female and 114(82%) male patients. The tumor location included the middle third of the esophagus in 11(8%) and lower third and gastroesophageal junction in 128(92%) patients. Ninety-three percent of patients had adenocarcinoma. Preoperative EUS matched the final surgical pathology in 73/139 patients for a concordance rate of 53%. Twenty-nine patients(21%) were under-staged by EUS; of those, 19(14%) had unrecognized nodal disease. Positron emission tomography(PET) was used in addition to EUS for clinical staging in 62/139 patients. Occult nodal disease was only found in 4 of 62 patients(6%) in whom both EUS and PET were negative for nodal involvement. CONCLUSION EUS is less accurate in early EC and endoscopic mucosal resection might be useful in certain settings. The addition of PET to EUS improves staging accuracy.Carrie Luu Marisa Amaral Jason Klapman Cynthia Harris Khaldoun Almhanna Sarah Hoffe Jessica Frakes Jose M Pimiento Jacques P Fontaine 2017World Journal of Gastroenterology2017,23,46:8
2Multicenter phase 1I randomized trial evaluating antiangiogenic therapy with sunitinib as consolidation after objective response to taxane chemotherapy in women with HER-2-negative metastatic breast cancer 显示文摘Wildiers H Fontaine C Vuylsteke P 2010Breast Cancer Res Treat2010,123,2:1
3Electrical conduction and deep levels in polycrystalline diamond films显示文摘 Deneuville A Fontaine F 1995J Appl Phys1995,78,11:1
4Atmospheric xenon radioactive isotope monitoring 显示文摘FONTAINE J P POINTURIER F BLAN- CHARD X 2004J Environ Radioact2004,72,:1
5Metformin-induced resumption of normal menses in 39 of 43 (91%) previously amenorrheic women with the polycystic ovary syndrome显示文摘Glueck C J Wang P Fontaine R 1999Metabolism1999,48,4:1
6TORA example: Cascade-and passivity-based control designs 显示文摘Jankovic M Fontaine D Kokotovie P V 1996IEEE Transactions on Control Systems Technology1996,4,3:1
7Induction of out of-season spawning in Eurasian perch Perca fluviatilis: effects of rates of cooling and cooling durations on female gametogenesis and spawning显示文摘MIGAUD H FONTAINE P SULISTYO I 2002Aquaculture2002,205,:1
8Progress on the mitochondrial permeability transition pore: regulation by complex I and ubiquinone analogs显示文摘Fontaine E Bernardi P 1999J Bioenerg Biomembr1999,31,4:1
9显示文摘Acher O Jacquart P M Fontaine J M 1994IEEE Trans Magn1994,30,6:1
10Metformin reduces weight,centripetal obesity,insulin,leptin,and low-density lipoprotein cholesterol in nandiabetic,morbidly obese subjects with body mass index greater than 30显示文摘GLUECK CJ FONTAINE RN WANG P 2001Metabolism2001,50,7:1
11Metformin-induced re- sumption of normal menses in 59 of 43 ( 91% ) previously a menor- rheic women with the polycystic ovary syndrome 显示文摘Glueck CJ Wang P Fontaine R 1999Metabolism1999,48,4:1
12New insights in the molecular biology and physiology of Streptococcus thermophilus revealed by comparative genomics显示文摘HOLS P HANCY F FONTAINE L 2005FEMS Microbiology Reviews2005,29,3:1
13Useful Nonlinearities and Global Stabilization of Bifurcations in a Model of Jet Engine Surge and Stall显示文摘Krstic M Fontaine D Kokotovic P V 1998IEEE Trans on Automatic Control1998,43,12:1
14Adoptive transfer of minor histocompatibility antigen-specific T lymphocytes eradicates leukemia cells without causing graft-versus-host disease显示文摘 Roy-Proulx G Knafo L Baron C Roy DC Perreault C 2001Nature Medcine2001,7,7:1
15Insulin analogues(insulin detemir and insulin aspart) versus traditional human insulin (NPH insulin and regular human insulin) in basal-bolus therapy for patients with typel diabetes显示文摘Hermansen K Fontaine P Kukoja 2004Diabetologia2004,47,4:1
16Intrathecal narcotics are associated with prolonged second-stage labor and increased oxytocin use 显示文摘Fontaine P Adam P 2000J Fam Pract2000,49,6:1
17Caffeine-withdrawal headache:A clinical profile显示文摘GRENEN JF VICTOR BS FONTAINE P 1980Psychosomatics1980,21,:1
18Screening of penicillin residues in milk by surface plasmon resonance based biosensor assay;comparison of chemical and enzymatic sample pretreatment显示文摘Gaudin V Fontaine J Maris P 2001Analytica Chimica Acta2001,436,:1
19Repolarization and the genesis of cardiac arrhythmias:role of body surface mapping显示文摘Fontaine G Aouate P Fontaliran F 1997Circulation1997,95,:1
20C-reactive protein and complement depositions in human infarcted myoeardium are more extensive in patients with reinfarction or upon treatment with reperfusion显示文摘Nijmeijer R Krijnen P Fontaine M 2001European Journal of Clinical Investigation2001,34,:1
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