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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: the PCI-CURE study显示文摘 | Shamir R Mehta Salim Yusuf Ron JG Peters Michel E Bertrand Basil S Lewis Madhu K Natarajan Klas Malmberg Hans-Jürgen Rupprecht Feng Zhao Susan Chrolavicius Ingrid Copland Keith AA Fox | 2001 | The Lancet . 2001 (9281)2001，，9281： | 4 |
| 3 | Synthesis,characterization and ctalytic applications of a palladlum-nanoparticle-cored dendrlmer显示文摘 | Gopidas K R Whitesell J K Fox M A | 2003 | Nano Lett2003，3，12： | 1 |
| 4 | Plasticity and stability of somatosensory maps in thalamus and cortex显示文摘 | Glazewski S Schulze S | 2000 | Cur Opin Neurobiol2000，10，4： | 1 |
| 5 | Angiotensin-converting-enzyme inhibitors in stable vascular disease without left ventricular systolic dysfunction or heart failure:a combined analysis of three trials显示文摘 | Dagenais GR Pogue J Fox K | 2006 | Lancet2006，368，9535： | 1 |
| 6 | Enhanced tumor killing by Apo2L/TRAIL and CPT-11 co-treatment is associated with p21 cleavage and differential regulation of Apo2L/TRAIL ligand and its receptors 显示文摘 | Xiang H Fox JA Totpal K | 2002 | Oncogene2002，21，： | 1 |
| 7 | Controlling cryptosporidium using conventional treatment 显示文摘 | Dugan N R Fox K R Owens J H | 2001 | J AWWA2001，93，12： | 1 |
| 8 | Mitochondria genome a rearrangement leads to extension and relocation of the cytochrome C oxidase Subunit I gene in sorghum显示文摘 | Bailey Serres J Hanson D K Fox T D | 1986 | Cell1986，47，： | 1 |
| 9 | The pathogenesis of atheroma and the rational for its treatment 显示文摘 | Collins P Fox K | 1992 | Eur Heart J1992，13，4： | 1 |
| 10 | Staudinger Reduction Chemistry of Cellulose: Synthesis of Selectively O-Acylated 6-Amino -6-deoxy-cellulose显示文摘 | Fox S C Edgar K J | 2012 | Biomacromolecules2012，13，4： | 1 |
| 11 | Nuclear locali- zation of Myomesin-l: Possible functions显示文摘 | Reddy K B Fox J E Priee M G | 2008 | Muscle Res Cell Motil2008，29，1： | 1 |
| 12 | Evaluation of a novel antiplatelet agent for secondary prevention in patients with a history of atherosclerotic disease: Design and rationale for the Thrombin Receptor Antagonist in Secondary Prevention of Atherothrombotic Ischemic Events(TRA 2°P)-TIMI 50 trial 显示文摘 | MORROW D A SCIRICA B M FOX K A | 2009 | Am Heart J2009，158，3： | 1 |
| 13 | Radiation dose reduction for CT lung cancer screening using ASIR and MBIR: a phantom study显示文摘 | Mathieu K B Ai H Fox P S | 2014 | J Appl Clin Med Phys2014，15，2： | 1 |
| 14 | TRANCE is necessary and sufficient for osteoblast-mediated activation of bone resorption in osteoclasts显示文摘 | Wong B Fox S | 1998 | J Exp Med1998，188，5： | 1 |
| 15 | The Psychology self-perception profile:Development and preliminary validation显示文摘 | Fox K R Corbin C B | 1989 | Journal of Sport and Exercise Psychology1989，11，： | 1 |
| 16 | Up regulation of basic fibroblast growth factor in breast carcinoma and its relationship to vascular density,oestrogen receptor,epidermal growth factor receptor and survival显示文摘 | Smith K Fox SB White house R | 1999 | Ann Oncol1999，10，6： | 1 |
| 17 | Performance and Properties of Mould Fluxes显示文摘 | Mills K C Fox A B Li Z | 2005 | Ironmaking Steelmaking2005，32，1： | 1 |
| 18 | Guidelines on the management of stable angina pectoris:executive summary:the Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology显示文摘 | Fox K Garcia MA Ardissino D | 2006 | Eur Heart J2006，27，： | 1 |
| 19 | Strategies for the rapid prenatal diagnosis of chromosome aneuploidy 显示文摘 | Mann K Donaghue C Fox SP | 2004 | Eur J Hum Genet2004，12，： | 1 |
| 20 | Smartest review of micro-simulation models显示文摘 | ALGERS S BERNAUER E BOERO M BREHERET L DI- TARANTO C DOUGHERTY M FOX K GABARD J F | 1997 | Transport RTD1997，，3： | 1 |
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