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1High-intensity focused ultrasound ablation:An effective bridging therapy for hepatocellular carcinoma patients显示文摘AIM:To analyze whether high-intensity focused ultrasound(HIFU) ablation is an effective bridging therapy for patients with hepatocellular carcinoma(HCC).METHODS:From January 2007 to December 2010,49 consecutive HCC patients were listed for liver transplantation(UCSF criteria).The median waiting time for transplantation was 9.5 mo.Twenty-nine patients received transarterial chemoembolization(TACE) as a bringing therapy and 16 patients received no treatment before transplantation.Five patients received HIFU ablation as a bridging therapy.Another five patients with the same tumor staging(within the UCSF criteria) who received HIFU ablation but not on the transplant list were included for comparison.Patients were comparable in terms of Child-Pugh and model for end-stage liver disease scores,tumor size and number,and cause of cirrhosis.RESULTS:The HIFU group and TACE group showed no difference in terms of tumor size and tumor number.One patient in the HIFU group and no patient in the TACE group had gross ascites.The median hospital stay was 1 d(range,1-21 d) in the TACE group and two days(range,1-9 d) in the HIFU group(P < 0.000).No HIFU-related complication occurred.In the HIFU group,nine patients(90%) had complete response and one patient(10%) had partial response to the treatment.In the TACE group,only one patient(3%) had response to the treatment while 14 patients(48%) had stable disease and 14 patients(48%) had progressive disease(P = 0.00).Seven patients in the TACE group and no patient in the HIFU group dropped out from the transplant waiting list(P = 0.559).CONCLUSION:HIFU ablation is safe and effective in the treatment of HCC for patients with advanced cirrhosis.It may reduce the drop-out rate of liver transplant candidate.Tan To Cheung Sheung Tat Fan See Ching Chan Kenneth SH Chok Ferdinand SK Chu Caroline R Jenkins Regina CL Lo James YY Fung Albert CY Chan William W Sharr Simon HY Tsang Wing Chiu Dai Ronnie TP Poon Chung Mau Lo 2013World Journal of Gastroenterology2013,19,20:23
2Electrochemdical and bioelectro chemistry properties of room-temperature ionic liquids and carbon composite materials 显示文摘Fung Y S Zhu D R Fung Y S Zhu D R 2002J Electrochem Soc2002,149,:1
3Abscisic acid inhibits type 2C protein phosphatases via the PYR/ PYL family of START proteins显示文摘PARK S Y FUNG P NISHIMURA N JENSEN D R FFUJII ZHAO Y LUMBA S SANTIAGO J RODRIGUES A CHOW T F 2009Science2009,324,:1
4Optimization of an impact drive mechanism based on real-coded genetic algorithm 显示文摘Ha J L Fung R F Han C F 2005Sensors and Actuators2005,121,2:1
5Current achievements using ProteinChip Array technology显示文摘Weinberger S R Dalmasso E A Fung E T 2002Curr Opin Chem Biol2002,6,1:1
6Room Temperature Molten Salt as Medium for Lithium Battery显示文摘Fung Y S Zhou R Q 1999J Power Sources1999,81,:1
7Activation of local renin angiotensin system by chronic hypoxia 显示文摘Chan WP Fung ML Nobiling R 2000Mol Cel Endocrinol2000,160,12:1
8GRIP:a synaptic PDZ domain-containing protein that interacts with AMPA receptors显示文摘Dong H O'Brien R J Fung E T 1997Nature1997,386,6622:1
9Optimization of an impact drive mechanism based on real-coded genetic algorithm显示文摘Ha J L Fung R F Han C F 0,,02:1
10Investor Legal Protection and Earnings Management:A Study of Chinese H-Shares and Hong Kong Shares显示文摘Fung S Y Su L Gul R J 2013Journal of Accounting and Public Policy2013,32,05:1
11Optimizing Timetable Synchronization for Rail Mass Transit 显示文摘Wong R C W Yuen T W Y Fung K W 2008Transportation Sci- ence2008,42,1:1
12Nutrient budgets in intensive shrimp ponds: implications for sustainability显示文摘FUNGE S BRIGGS M R P 1998Aquaculture1998,164,18:1
13Activation of local renin-angiotensin system by chronic hypoxia in rat pancreas显示文摘Chan WP Fung ML Nobiling R 2000Mol Cell Endocrinol2000,160,12:1
14A new approach to quality function deployment planning with financial consideration 显示文摘TANG J F FUNG R Y K XU B 2002Computer and Operation Research2002,29,11:1
15Intracoronary imaging of coronary fibromuscular dysplasia with OCT and IVUS显示文摘SAW ] POULTER R FUNG A 2013Catheter Cardiovasc Interv2013,82,7:1
16Non-linearly dynamicmodeling of an axially moving beam with a tip mass显示文摘Fung R F Lu P Y Tseng C C 1998Journal of Sound and Vibration1998,218,4:1
17Mechanical Properties of Short Glass Fibre Reinforced and Functionahzed Rubber-Toughened PET Blends显示文摘Fung K L Li R K Y 2006Polym Test2006,25,7:1
18Dynamic stability of viscoelastic beam subjected to harmonic and parametric excitations simultaneously 显示文摘R F Fung J S Huang W H Chen 1996Journal of Sound and Vibration1996,198,1:1
19Modeling of cavity stability and sand production in heavy oil reservoir显示文摘Fung L S K Wong R C K 1996JCPT1996,35,2:1
20Cost engineering with quality function deployment显示文摘Bode J Fung R Y K 1998Computers & Industrial Engineering1998,35,34:1
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