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59篇 您的检索式:作者名="Furqan"
    题名 作者 年代 出处 被引量
1南京地区某渔场嗜水气单胞菌流行菌株的鉴定及分子分型显示文摘为确定南京地区某渔场异育银鲫出血性败血症的病原体,采集该渔场3个饲养塘口患病鱼脏器进行细菌分离培养,基于气单胞菌DNA促旋酶B亚单位(gyr B)基因序列设计引物,PCR扩增后测序进行细菌鉴定;同时,对病原菌生物学特性如溶血性、蛋白酶活性、生物被膜形成能力、运动能力以及对斑马鱼的毒力等进行分析,并进行多位点序列分型(MLST)。结果在3个饲养塘口均分离到嗜水气单胞菌,分别命名为GL-15、GL-17和GL-18;MLST分型显示三株分离菌均为ST251型;生物学特性实验表明,均有溶血性、蛋白酶活性以及运动性,生物被膜形成能力较强,OD595均超过0.5,对斑马鱼的LD50在1.4×103~3.9×103 CFU/尾,属强毒株。本研究为有效防控南京地区嗜水气单胞菌引发的出血性败血症的暴发流行提供了依据。曹青 张向阳 庞茂达 王楠楠 FURQAN Awan 陆承平 刘永杰 2017水产学报2017,41,1:10
2Spontaneous fungal peritonitis: Micro-organisms, management and mortality in liver cirrhosis-A systematic review显示文摘BACKGROUND Spontaneous peritonitis is an infection of ascitic fluid without a known intraabdominal source of infection. spontaneous fungal peritonitis (SFP) is a potentially fatal complication of decompensated cirrhosis, defined as fungal infection of ascitic fluid in the presence of ascitic neutrophil count of greater than 250 cells/mL. AIM To determine the prevalence of fungal pathogens, management and outcomes (mortality) of SFP in critically ill cirrhotic patients. METHODS Studies were identified using PubMed, EMBASE, Cochrane Central Register of Controlled Trials and Scopus databases until February 2019. Inclusion criteria included intervention trials and observation studies describing the association between SFP and cirrhosis. The primary outcome was in-hospital, 1-mo, and 6- mo mortality rates of SFP in cirrhotic patients. Secondary outcomes were fungal microorganisms identified and in hospital management by anti-fungal medications. The National Heart, Lung and Blood Institute quality assessment tools were used to assess internal validity and risk of bias for each included study. RESULTS Six observational studies were included in this systematic review. The overall quality of included studies was good. A meta-analysis of results could not be performed because of differences in reporting of outcomes and heterogeneity of the included studies. There were 82 patients with SFP described across all the included studies. Candida species, predominantly Candida albicans was the fungal pathogen in majority of the cases (48%-81.8%) followed by Candida krusei (15%- 25%) and Candida glabrata (6.66%-20%). Cryptococcus neoformans (53.3%) was the other major fungal pathogen. Antifungal therapy in SFP patients was utilized in 33.3% to 81.8% cases. The prevalence of in hospital mortality ranged from 33.3% to 100%, whereas 1-mo mortality ranged between 50% to 73.3%. CONCLUSION This systematic review suggests that SFP in end stage liver disease patient is associated with high mortality both in the hospital and at 1-mo, and that antifungal therapy is currently underutilized.Tooba Tariq Furqan B Irfan Mehdi Farishta Brian Dykstra Eric Martin Sieloff Archita P Desai 2019World Journal of Hepatology2019,11,7:7
3Model design and structure research for integration system of energy, information and transportation networks based on ANP-fuzzy comprehensive evaluation显示文摘For lack of deep research on model, system structure and top-level design, the integrated system concept of energy, information and transportation networks fails to provide effective guidance for transferring the theory to practice. In this paper, with dispatching of energy flow and information flow as a focus, clean energy of wind power and solar power as carrier, battery charging & swapping station as medium and all kinds of transportation flows as entity, a five-in-one threenetwork integrated system model is built by full use of technologies of Internet of Vehicles(IOV) and Internet of things(IOT) to promote the innovative concept of three-network integration into practice, and provide a reference for future researches.Tianjing Wu Shaohua Liu Ming Ni Yong Zhao Pei Shen Syed Furqan Rafique 2018Global Energy Interconnection2018,1,2:7
4Secondary angiodysplasia-associated gastrointestinal bleeding in end-stage renal disease: Results from the nationwide inpatient sample显示文摘BACKGROUND Chronic kidney disease is associated with angiodysplasia of gastrointestinal tract leading to increased risk of gastrointestinal bleeding.AIM To determine the nationwide prevalence,trends,predictors and resource utilization of angiodysplasia-associated gastrointestinal bleeding in end-stage renal disease hospitalizations.METHODS The Nationwide Inpatient Sample database from 2009 to 2014,was utilized to conduct a retrospective study on patients with angiodysplasia associatedgastrointestinal bleeding and end-stage renal disease.Hospitalizations with endstage renal disease were included in the Nationwide Inpatient Sample database and a subset of hospitalizations with end-stage renal disease and angiodysplasiaassociated gastrointestinal bleeding were identified with International Classification of Diseases,9th revision,Clinical Modification codes for both endstage renal disease(585.6)and angiodysplasia(569.85,537.83).RESULTS The prevalence of angiodysplasia-associated gastrointestinal bleeding was 0.45%(n=24709)among all end-stage renal disease patients(n=5505252)that were hospitalized.Multivariate analysis indicated that the following were significant factors associated with higher odds of angiodysplasia associated-gastrointestinal bleeding in end-stage renal disease patients:an increasing trend from 2009-2014(P<0.01),increasing age(P<0.0001);African American race(P=0.0206);increasing Charlson-Deyo Comorbidity Index(P<0.01);hypertension(P<0.0001);and tobacco use(P<0.0001).Diabetes mellitus(P<0.0001)was associated with lower odds of angiodysplasia associated-gastrointestinal bleeding in end-stage renal disease patients.In comparison with urban teaching hospitals,rural and urban nonteaching hospitals were associated with decreased odds of angiodysplasia associated-gastrointestinal hemorrhage.CONCLUSION Angiodysplasia-associated gastrointestinal bleeding in end-stage renal disease patients showed an increasing trend from 2009-2014.Advanced age,African American race,overall high comorbidities,hypertension and smoking were significant factors for angiodysplasia-associated gastrointestinal bleeding in bleeding in these patients.Tooba Tariq Patrick Karabon Furqan B Irfan Sachin Goyal Matthew Masaru Mayeda Austin Parsons Stephanie Judd Murray Ehrinpreis 2019World Journal of Gastrointestinal Endoscopy2019,11,10:3
5媒体对公共政策过程影响研究综述:“传统媒体”框架的失灵与“社交媒体”框架的缺失显示文摘媒体通过对政策渐进式的影响,不断促进社会形态的嬗变。面对变革,我国学界还未能从'传统媒体'的框架中摆脱'路径依赖',传统媒体长期以来处于行政隶属地位,使得其他利益诉求难以在传统媒体上发声;而'社交媒体'的兴起又进一步分化了'传统媒体'对公共政策过程的影响力。'运动式'的媒介公共政策动员手段导致意见的撕裂,地方'传统媒体'一片叫好,'社交媒体'不乏争议。这是因为我国还未形成系统的'社交媒体'的公共政策过程影响管理机制,主要表现在以下几个方面:未能给相关管理部门提供足够的社交媒体治理经验,缺乏社交媒体对公共政策过程从'问题产生'到'效果评估'各阶段影响方式和作用的详尽分析,未建立起与社交媒体对应的政策过程传播管理框架,社交媒体的管理仍停留在'消极管理'阶段,缺少'积极管理'机制。文章试从传播学、公共政策过程理论出发,利用框架分析与对比研究的方法,综述当前'传统媒体'与'社交媒体'对公共政策过程影响存在的差异因素、国内'传统媒体'影响公共政策过程框架失灵的原因以及'社交媒体'框架对公共政策过程影响研究的缺失。张焱 戴楷然 支宇珩 MUHAMMAD Furqan Rao 2018西华大学学报(哲学社会科学版)2018,37,5:3
650 years of scanning electron microscopy of bone——a comprehensive overview of the important discoveries made and insights gained into bone material properties in health,disease,and taphonomy显示文摘Bone is an architecturally complex system that constantly undergoes structural and functional optimisation through renewal and repair.The scanning electron microscope (SEM) is among the most frequently used instruments for examining bone.It offers the key advantage of very high spatial resolution coupled with a large depth of field and wide field of view.Interactions between incident electrons and atoms on the sample surface generate backscattered electrons,secondary electrons,and various other signals including X-rays that relay compositional and topographical information.Through selective removal or preservation of specific tissue components (organic,inorganic,cellular,vascular),their individual contribution(s) to the overall functional competence can be elucidated.With few restrictions on sample geometry and a variety of applicable sample-processing routes,a given sample may be conveniently adapted for multiple analytical methods.While a conventional SEM operates at high vacuum conditions that demand clean,dry,and electrically conductive samples,non-conductive materials (e.g.,bone) can be imaged without significant modification from the natural state using an environmental scanning electron microscope.This review highlights important insights gained into bone microstructure and pathophysiology,bone response to implanted biomaterials,elemental analysis,SEM in paleoarchaeology,3D imaging using focused ion beam techniques,correlative microscopy and in situ experiments.The capacity to image seamlessly across multiple length scales within the meso-micro-nano-continuum,the SEM lends itself to many unique and diverse applications,which attest to the versatility and user-friendly nature of this instrument for studying bone.Significant technological developments are anticipated for analysing bone using the SEM.Furqan A.Shah Krisztina Ruscsák Anders Palmquist 2019Bone Research2019,7,2:2
7Reliability Assessment of a Cyber Physical Microgrid System in Island Mode显示文摘As cyber physical systems,microgrids(MGs),with distributed generations and energy management systems,can improve the reliability of power supply for customers in MGs.To quantify the reliability of isolated MGs,a cyber-physical assessment model is proposed.In this model,the circuit breakers and distributed energy resources are treated as the coupling elements between the cyber system and physical system,where the circuit breakers are uniquely modelled by using the Markov process theory based on the indirect interdependencies between cyber physical elements.For the cyber system,the reliability model of communication networks is formulated based on the link connectivity evaluation method.For the physical system,a system state generating method is presented to account for the optimal operation strategy,which considers the influence of the optimization strategy on the failure consequence analysis.With the proposed cyber and physical reliability models,the sequential Monte Carlo(SMC)simulation method is adopted to assess the reliability of islanded MGs.Simulations are carried out on a test system,and results verify the feasibility and effectiveness of proposed assessment method.Furthermore,one application of the proposed method is on the parameter setting of the cyber system,in terms of enhancing MGs reliability.Jing Guo Wenxia Liu Furqan R.Syed Jianhua Zhang 2019CSEE Journal of Power and Energy Systems2019,5,1:2
8Dysregulation of JAK-STAT pathway in hematological malignancies and JAK inhibitors for clinical applieation显示文摘Furqan M Mukhi N Lee B 2013Biomark Res2013,1,1:1
9Conversion of autoimmune hypothyroidism to hyperthyroidism显示文摘Furqan S Haque NU Islam N 2014BMC Res Notes2014,7,1:1
10Phosphatidylinositol 3-kinase (PI3K) inhibitors as cancer therapeutics显示文摘Akinleye A Avvaru P Furqan M 2013J Hematol Oncol2013,6,1:1
11Ibruti- nib and indolent B-cell lymphomas 显示文摘AKINLEYE A FURQAN M ADEKUNLE O 2014Clin Lymph Myelom Leuk2014,14,4:1
12Venoarterial PCO2 difference: a maeker of postoperative cardiacoutput in children with congenital heart disease显示文摘Furqan M Hashmat F Amanullah M 2009J CoU Physicians Sury Pak2009,19,10:1
13APACHE 11 scores as pre- dictors of cardiopulmonary resuscitation outcome : evidence from a tertiary care institute in a low - income country 显示文摘Patel MJ Khan NU Furqan M 2012Saudi J Anaesth2012,6,1:1
14Robust feedback model predictive control of constrained uncertain systems 显示文摘Furqan Tahir Imad M Jaimoukha 2013Journal of Process Control2013,23,2:1
15Phosphatidylinositol 3 - kinase (PI3K) inhibitors as cancer therapeutics 显示文摘Akinleye A Avvaru P Furqan M 2013JHematol Oncol2013,6,1:1
16MEK and the inhibitors : from bench to bedside 显示文摘Akinleye A Furqan M Mukhi N 2013J Hematol Oncol2013,6,1:1
17Dysregulation of JAK-STAT pathway in hematological malignancies and JAK inhibitors for clinical application 显示文摘Furqan M Mukhi N Lee B 2013Biomarker Research2013,1,1:1
18Dysregulation of JAK-STATpathway in hematological malignancies and JAK inhibitors for clinicalapplication显示文摘Furqan M Mukhi N Lee B 2013Biomark Res2013,1,:1
19Frequency of Streptococcus pneumonia and Haemophilus influenza in acute exacerbation of chronic obstructive airway disease and their sensitivitytolevofloxacin显示文摘Furqan S Paracha SA 2014JPakMedAssoc2014,64,4:1
20Venoarteri- al PCO2 difference;a marker of postoperative cardiac out- put in children with congenital heart diaease显示文摘Furqan M Hashmat F Amanullah M 2009J Coll Physicians Surg Pak2009,19,10:1
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