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194篇 您的检索式:作者名="GIUDICE L"
    题名 作者 年代 出处 被引量
1A systematic review and meta-analysis of clinical trials implementing aromatase inhibitors to treat male infertility显示文摘Aromatase activity has commonly been associated with male infertility characterized by testicular dysfunction with low serum testosterone and/or testosterone to estradiol ratio.In this subset of patients,and particularly in those with hypogonadism,elevated levels of circulating estradiol may establish a negative feedback on the hypothalamic–pituitary–testicular axis by suppressing follicle-stimulating hormone(FSH)and luteinizing hormone(LH)production and impaired spermatogenesis.Hormonal manipulation via different agents such as selective estrogen modulators or aromatase inhibitors to increase endogenous testosterone production and improve spermatogenesis in the setting of infertility is an off-label option for treatment.We carried out a systematic review and meta-analysis of the literature of the past 30 years in order to evaluate the benefits of the use of aromatase inhibitors in the medical management of infertile/hypoandrogenic males.Overall,eight original articles were included and critically evaluated.Either steroidal(Testolactone)or nonsteroidal(Anastrozole and Letrozole)aromatase inhibitors were found to statistically improve all the evaluated hormonal and seminal outcomes with a safe tolerability profile.While the evidence is promising,future prospective randomized placebo-controlled multicenter trials are necessary to better define the efficacy of these medications.Francesco Del Giudice Gian Maria Busetto Ettore De Berardinis Isabella Sperduti Matteo Ferro Martina Maggi Martin S Gross Alessandro Sciarra Michael L Eisenberg 2020Asian Journal of Andrology2020,22,4:5
2Endometriosis显示文摘Giudice L C Clinical practice 0,,25:1
3Endometriosis显示文摘Giudice L C Kao L C 0,,9447:1
4Tripigmented anticorrosive coatings based on lamellar zinc as inhibitor 显示文摘PEREYRA A M GIUDICE C A HERRERA L K 2006Surface Coatings International Part B: Coatings Transactions2006,89,3:1
5The diagnostic value of CD123 in B-cell disorders with hairy or villous lymphocytes 显示文摘Del Giudice L Matutes E Monlla R 2004Haemat Ologiea2004,89,3:1
6Lipolytic activity of Antarctic cold-adapted marine bacteria (Terra Nova Bay, Ross Sea)显示文摘Lo Giudice A Michaud L De Pascale D 2006Journal of Applied Microbiology2006,101,5:1
7Endometriosis 显示文摘Giudice L C Kao L C 2004Lancet2004,364,:1
8The influence of hydrosalpix on markers of endometrial receptivity 显示文摘Savaris R F Giudice L C 2007Semin Reprod Med2007,25,6:1
9Discovery of new inducible genes in vitro decidualized human endometrial stromal cells using microarray technology 显示文摘Popovici R M Kao L C Giudice L C 2000Endocrinology2000,141,9:1
10Cryopreservation of embryos and ova显示文摘Friedler S Giudice L C Lamb E J 1988Fertil Sertil1988,49,:1
11Status of current research on endometriosis显示文摘Giudice LC Tazuke SI Swiersz L 1998J Reprod Med1998,43,:1
12Lincomycin solar photodegradation, algal toxicity and removal from wastewaters by means of ozonation显示文摘Andreozzi R Canterino M Giudice R L 2006Water Research2006,40,:1
13Molecular evidence for differences in endometrium in severe versus mild endome- triosis显示文摘AQHAJANOVA L GIUDICE L C 2010Reprod Sci2010,18,3:1
14Endometriosis 显示文摘Giudice L C Kao L C 2004Lancet2004,364,9447:1
15Role of laparoscopi treatment of endometriosis in patients with failed in vitro fertilization eycles显示文摘Littman E Giudice L Lathi R 2005Fertil Steril2005,84,6:1
16Endometrium in PCOS: implantation and predisposition to endocrine CA 显示文摘Giudice L C 2006Best Pract Res Clin EndocrinoL Metab2006,20,2:1
17Elucidating endometrial function in the post-genomicera显示文摘Giudice L C 2003Hum Reprod Update2003,9,3:1
18Endometriosis显示文摘Giudice L C Kao L C 2004Lancet2004,364,9447:1
19Ownership structure,family control and acquisition decisions 显示文摘Caprio L Croci E Del Giudice A 2011Journal of Corporate Fi- nance2011,,17:1
20Role of laparoscopic treatment of endometriosis in patients with failed in vitro fertilization cycles显示文摘Litm an E Giudice L Lathi R 2005Fertil Steril2005,84,6:1
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