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| 1 | Multimodality functional imaging using DW-MRI and 18F-FDG-PET/CT during radiation therapy for human papillomavirus negative head and neck squamous cell carcinoma: Meixoeiro Hospital of Vigo Experience显示文摘AIM To noninvasively investigate tumor cellularity measured using diffusion-weighted magnetic resonance imaging(DW-MRI) and glucose metabolism measured by 18 Flabeled fluorodeoxyglucose positron emission tomography/computed tomography(18F-FDG-PET/CT) during radiation therapy(RT) for human papillomavirus negative(HPV-) head and neck squamous cell carcinoma(HNSCC).METHODS In this prospective study, 6 HPV- HNSCC patients underwent a total of 34 multimodality imaging examinations(DW-MRI at 1.5 T Philips MRI scanner [(n = 24) pre-, during-(2-3 wk), and post-treatment(Tx), and 18F-FDG PET/CT pre- and post-Tx(n = 10)]. All patients received RT. Monoexponential modeling of the DW-MRI data yielded the imaging metric apparent diffusion coefficient(ADC) and the mean of standardized uptake value(SUV) was measured from 18F-FDG PET uptake. All patients had a clinical follow-up as the standard of care and survival status was documented at 1 year.RESULTS There was a strong negative correlation between the mean of pretreatment ADC(ρ =-0.67, P = 0.01) and the pretreatment 18F-FDG PET SUV. The percentage(%) change in delta(?) ADC for primary tumors and neck nodal metastases between pre- and Wk2-3 Tx were as follows: 75.4% and 61.6%, respectively, for the patient with no evidence of disease, 27.5% and 32.7%, respectively, for those patients who were alive with disease, and 26.9% and 7.31%, respectively, for those who were dead with disease.CONCLUSION These results are preliminary in nature and are indicative, and not definitive, trends rendered by the imaging metrics due to the small sample size of HPV- HNSCC patients in a Meixoeiro Hospital of Vigo Experience. | David Aramburu Núnez Antonio Lopez Medina Moisés Mera Iglesias Francisco Salvador Gomez Abhay Dave Vaios Hatzoglou Ramesh Paudyal Alfonso Calzado Joseph O Deasy Amita Shukla-Dave Victor M Munoz | 2017 | World Journal of Radiology2017，9，1： | 2 |
| 2 | Completely autotrophic nitrogen removal over nitrite in one single reactor 显示文摘 | Sliekers A O Derworth N Gomez J L C | 2002 | Water Research2002，36，： | 1 |
| 3 | Gas dispersion measurements in flotation cells 显示文摘 | GOMEZ C O FINCH J A | 2007 | International Journal of Mineral Processing2007，84，： | 1 |
| 4 | Treatment of infantile hemangiomas with short-term application of imiquimod 5% cream显示文摘 | Welsh O Olazaran Z Gomez M | 2004 | J Am Acad Dermatol2004，51，4： | 1 |
| 5 | KLF4 dependent phenotypic modulation of smooth muscle ceils has a key role in atherosclerotie plaque pathogenesis 显示文摘 | SHANKMAN L S GOMEZ D CHEREPANOVA O A | 2015 | Nat Med2015，21，6： | 1 |
| 6 | Genomic analysis and gene structure of the plant carotenoid dioxygenase 4 family: A deeper study in Crocus sativus and its allies 显示文摘 | Ahrazem O Trapero A Gomez M D | 2010 | Genomics2010，96，： | 1 |
| 7 | Viscometric Study on the Compatibility of Polymer - Polymer Mixtures in Solution显示文摘 | Garcia R Melad O Gomez C M | 1999 | Europe Polymer1999，35，： | 1 |
| 8 | IGF1R gene expression as a predictive marker of re- sponse to ionizing radiation for patients with locally ad- vanced HPV16-positive cervical cancer显示文摘 | Moreno-Acosta P Gamboa O Sanchez de Gomez M | 2012 | Anticancer Re- s2012，32，10： | 1 |
| 9 | Staphylococcus aureusprotein Aactivates TNFR1 signaling through conserved IgG bindingdomains 显示文摘 | Gomez M I O'Seaghdha M Magargee M | 2006 | J Biol Chem2006，281，20： | 1 |
| 10 | Inhibin A serum levels in proteinuric and nonproteinuric pregnancy-induced hypertension: Evidence for placental involvement in gestational hypertension显示文摘 | Casals E Gomez O Aibar C Cararach V Alonso PL Fortuny A | 2000 | Hypertens Preg2000，19，3： | 1 |
| 11 | Systemic and local effects of angiotensin II blockade in experimental diabetic nephropathy显示文摘 | Vieitez P Gomez O Uceda ER | 2008 | Renin Angiotensin Aldosterone Syst2008，9，2： | 1 |
| 12 | 查看详情显示文摘 | Illa O Garcia C.R Silva C.A Favier I. Picurelli D. Oliva A. Gomez M. Branchadell V. Ortuno R.M | | 0，，： | 1 |
| 13 | The iFlow address process显示文摘 | Mike O'connor Christopher Gomez | 2001 | IEEE Micro2001，21，3： | 1 |
| 14 | Systemic and local effects of angiotensin II blockade in experimental diabetic nephropathy 显示文摘 | Vieitez P Gomez O Uceda ER | 2008 | J Renin Angiotensin Aldosterone Syst2008，9，2： | 1 |
| 15 | Direct evidence for chronicstress-induced acilitation of the adrenocorticotrophic in response to a acute stressor显示文摘 | Marti O Gavalda A Gomez F | 1994 | Nuroendocrinology1994，60，1： | 1 |
| 16 | Frother persistence: A measure using gas holdup 显示文摘 | AZGOMI F GOMEZ C O FINCH J A | 2009 | Minerals Engineering2009，22，： | 1 |
| 17 | Mifepristone -misoprostol midtrimester abortion : impact of gestational age on the induction - to - abortion interval显示文摘 | Gomez O Borras A Rabanal A | 2010 | Contraception2010，81，： | 1 |
| 18 | Unified mechanistic model for steady state two-phase flow: Hori zontal to vertical upward flow显示文摘 | GOMEZ L E SHOHAM O SCHMIDT Z | 2000 | SPE Journal2000，5，3： | 1 |
| 19 | Accuracy of four- dimensional spatiotemporal image correlation echoeardiography in the prenatal diagnosis of congenital heart defects显示文摘 | Bennasar M Martinez JM Gomez O | 2010 | Ultrasound Obstet Gynecol2010，36，4： | 1 |
| 20 | An experimental study examining the relationship between bubble shape and rise velocity显示文摘 | MALDONADO M QUINN J J GOMEZ C O | 2013 | Chemical Engineering Science2013，98，29： | 1 |
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