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| 1 | Experimental study of“Tong Xia”purgative method in ameliorating lung injury in acute necrotizing pancreatitis显示文摘AIM To investigate the role of tumor necrosisfactor(TNF)in lung injury during acutenecrotizing pancreatitis(ANP),and thetherapeutic effect of'Tong Xia'purgativemethod in minimizing the severity of lung injury.METHODS Fourteen canines were randomlydivided into 3 groups:the'Tong Xia'treatmentgroup(n = 5)using Dachengqitang;salinecontrol group(n = 5),and the sham operationgroup(n = 4).TNF activity in serum and inbronchoalveolar lavage fluid(BALF),the serumendotoxin levels were measured,and theseverity of lung injury evaluated.RESULTS Elevation of TNF activity was moreprominent in BALF than in serum.TNF activity inserum at 6 and 12 hours and in BALI:wassignificantly decreased in the'Tong Xia'treatment group than in the saline control one(q=21.11,q=12.07,q=9.03,respectively,P<0.01)and the lung injury was significantlyalleviated at 12 hours as compared with that inthe saline group,manifested as amelioration otthe lung wet/ dry weight ratio,decrease inprotein concentration and neutrophils count inBALF,and improvement of pulmonaryinflammatory changes.A positive correlationwas demonstrated between serum TNF activity and endotoxin level.CONCLUSION Hypersecretion of TNF is shownto be one of the major causes of lung injuryduring ANP;'Tong Xia'purgative method couldalleviate the degree of lung injury mediated byTNF. | Xia Q Jiang JM Gong X Chen GY Li L Huang ZW | 2000 | World Journal of Gastroenterology2000，6，1： | 31 |
| 2 | Vascular endothelial growth factor receptor 2(VEGFR-2) plays a key role in vasculogenic mimicry formation,neovascularization and tumor initiation by Glioma stem-like cells显示文摘Human glioblastomas(GBM)are thought to be initiated by glioma stem-like cells(GSLCs).GSLCs also participate in tumor neovascularization by transdifferentiating into vascular endothelial cells.Here,we report a critical role of GSLCs in the formation of vasculogenic mimicry(VM),which defines channels lined by tumor cells to supply nutrients to early growing tumors and | Yao X Ping Y Liu Y Chen K Yoshimura T Liu M Gong W Chen C Niu Q Guo D Zhang X Wang JM Bian X | 2013 | 中国神经肿瘤杂志2013，11，3： | 23 |
| 3 | Concurrent alterations of O-GlcNAcylation and phosphorylation of tau in mouse brains during fasting.显示文摘 | Li X Lu F Wang JZ Gong CX | 2006 | 中国生物学文摘2006，20，9： | 12 |
| 4 | Expression of the cystic fibrosis transmembrane conductance regulator in rat spermatids: implication for the site of antispermatogenic agents显示文摘 | Gong X D Li J C Cheung K H | 2001 | Mol Hum Reprod2001，7，8： | 2 |
| 5 | Different Paterns of apoptosis of HL -60 cell induced by Cycloheximide and Camptothecin显示文摘 | GONG J LI X DATZYR KIEWIC Z | 1993 | J cell physiol1993，157，： | 1 |
| 6 | Stromal cell derived factor-1 acutely promotes neural progenitor cell proliferation in vitro by a mechanism involving the ERK1/2 and PI-3K signal pathways显示文摘 | Gong X He X Qi L | 2006 | Cell Biol Int2006，30，5： | 1 |
| 7 | Electrophosphorescence from a conjugated copolymer doped with an iridium complex: high brightness andimproved operational stability显示文摘 | Gong X Ostrowski J C Bazan G C | 2003 | Advanced Materials2003，15，1： | 1 |
| 8 | Annealing effects on electrical and optical properties of ZnO thin film samples deposited by radio frequency magnetron sputtering on GaAs(001) substrates显示文摘 | LIU H F CHUA S J HU G X GONG H XIANG N | 2007 | Journal of Applied Physics2007，102，6： | 1 |
| 9 | Generation of dual wavelength ultrashort pulse outputs from a passive mode locked fiber ring laser显示文摘 | Gong Y D Tian X L Tang M | 2006 | Optics Communications2006，265，： | 1 |
| 10 | Simultaneous production and recovery of fumaric acid from immobilized Rhizopus oryzae with a rotary biofilm contactor and an adsorption column 显示文摘 | Cao N J Du J X Gong C S | 1996 | Applied and Environmental Microbiology1996，62，8： | 1 |
| 11 | Luminescent properties of Sr2 MgSi2 07 : Eu2 - as blue phosphor for NUV light-emitting diodes显示文摘 | Zhang X G Tang X P Zhang J L Wang H H Shi J X Gong M L | 2010 | Powder Technology2010，204，： | 1 |
| 12 | Nanostructured Li2FeSiO4 electrode material synthesized through hydrothermal-assisted sol-gel process显示文摘 | Gong Z L Li Y X He G N | 2008 | Electrochem Solid-State Lett2008，11，5： | 1 |
| 13 | Fabrication and mierostructure of in situ toughened Al2O3/Fe3 Al显示文摘 | Gong H Y Yin Y S Wang X | 2004 | Materials Research Bulletin2004，39，45： | 1 |
| 14 | Asian dust storm influence on North American ambient PM levels: observational evidence and controlling factors 显示文摘 | Zhao T L Gong S L Zhang X Y | 2008 | Atmospheric Chemistry and Physics2008，8，： | 1 |
| 15 | A DS-AHP approach for multi attribute decision making problem with incomplete information显示文摘 | Hua Z S Gong B G Xu X Y | 2008 | Expert Systems with Applications2008，34，3： | 1 |
| 16 | Scalarization and optimality conditions for vector equilibrium problems 显示文摘 | GONG X H | 2010 | Nonlinear Analysis2010，73，： | 1 |
| 17 | Fast speciation of mercury in seawater by short-column high-performance liquid chromatography hyphenated to inductively coupled plasma spectrometry after on-line cation exchange column preconcentration 显示文摘 | Jia X Y Gong D R Han Y Wei C Duan T C Chen H T | 2012 | Talanta2012，88，： | 1 |
| 18 | High proportion of 22q13 deletions and SHANK3 mutations in Chinese patients with intellectual disability显示文摘 | Gong X Jiang YW Zhang X | 2012 | PIoS One2012，7，34： | 1 |
| 19 | Determining socioeconomicdrivers of urban forest fragmentation with historical remote sens-ing images显示文摘 | Gong C F Yu S X Joesting H | 2013 | Landscape and Urban Planning2013，117，9： | 1 |
| 20 | Cdk5-mediated inhibition of the protective effects of transcription factor MEF2 in neurotoxicityinduced apoptosis显示文摘 | Gong X Tang X Wiedmann M | | 0，，01： | 1 |
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