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| 1 | Control of stem cell fate by engineering their micro and nanoenvironment显示文摘Stem cells are capable of long-term self-renewal and differentiation into specialised cell types, making them an ideal candidate for a cell source for regenerative medicine. The control of stem cell fate has become a major area of interest in the field of regenerative medicine and therapeutic intervention. Conventional methods of chemically inducing stem cells into specific lineages is being challenged by the advances in biomaterial technology, with evidence highlighting that material properties are capable of driving stem cell fate. Materials are being designed to mimic the clues stem cells receive in their in vivo stem cell niche including topographical and chemical instructions. Nanotopographical clues that mimic the extracellular matrix(ECM) in vivo have shown to regulate stem cell differentiation. The delivery of ECM components on biomaterials in the form of short peptides sequences has also proved successful in directing stem cell lineage. Growth factors responsible for controlling stem cell fate in vivo have also been delivered via biomaterials to provide clues to determine stem cell differentiation. An alternative approach to guide stem cells fate is to provide genetic clues including delivering DNA plasmids and small interfering RNAs via scaffolds. This review, aims to provide an overview of the topographical, chemical and molecular clues that biomaterials can provide to guide stem cell fate. The promising features and challenges of such approaches will be highlighted, to provide directions for future advancements in this exciting area of stem cell translation for regenerative medicine. | Michelle F Griffin Peter E Butler Alexander M Seifalian Deepak M Kalaskar | 2015 | World Journal of Stem Cells2015，7，1： | 3 |
| 2 | 非甾体抗炎药应用中,环氧合酶2、不对称二甲基精氨酸与心血管危害的关系显示文摘已有大规模、安慰剂对照试验确定了非甾体类抗炎药(nonsteroidal anti—inflammatory drugs,NSAIDs)具有心血管危害性:这归因于环氧合酶2(cyclooxygenase,COX-2)的心脏保护产物受到抑制,尤其是前列环素(prostacyclin,PG12)。NSAID降低心脏保护作用的另一种机制可能是通过增强肾脏中甲基精氨酸的形成来限制一氧化氮在整个脉管系统中的作用。 | Ricciotti E Castro C Tang SY Briggs WTE West JA Malik D Rhoades SD Meng H Li X Lahens NF Sparks JA Karlson EW Weljie AM Griffin JL FitzGerald GA6 刘青 叶鹏 | 2018 | 中华高血压杂志2018，26，9： | 3 |
| 3 | Inflammation and Alzheimer’s disease显示文摘 | Haruhiko Akiyama Steven Barger Scott Barnum Bonnie Bradt Joachim Bauer Greg M Cole Neil R Cooper Piet Eikelenboom Mark Emmerling Berndt L Fiebich Caleb E Finch Sally Frautschy W.S.T Griffin Harald Hampel Michael Hull Gary Landreth Lih–Fen Lue Robert Mrak | 2000 | Neurobiology of Aging2000，，3： | 2 |
| 4 | Free fatty acid-iduced insulin resistance is associated with activation of protein kinase Cθ and alterations in the insulin signaling cascade显示文摘 | Griffin Melissa J | 1999 | Diabetes1999，48，6： | 1 |
| 5 | Willingness to pay for flood and ecological risk reduction in an urban watershed显示文摘 | Clark D E Novotny V Griffin R | 2001 | Water Science & Technology2001，45，9： | 1 |
| 6 | Evaluation of a taurine containing amino acid solution in parenateral nutrition显示文摘 | Thornton L Griffin E | 2000 | Arch Dis Child2000，24，： | 1 |
| 7 | Toward a theory of organizational creativity显示文摘 | Woodman R W Sawyer J E Griffin R W | 1993 | Academy of Management Review1993，，18： | 1 |
| 8 | The Satisfaction with Life Scale显示文摘 | Diener E Emmons R A Larsen R J Griffin S | 1985 | Journal of personality assessment1985，49，1： | 1 |
| 9 | Muhistate outbreak of listeriosis linked to turkey dell meat and subsequent changes in US regulatory policy 显示文摘 | GOTTLIEB S L NEWBERN E C GRIFFIN P M | 2006 | Clin Infect Dis2006，42，1： | 1 |
| 10 | The applica- tion of laser ablation-inductively coupled plasma-mass spectrometry to in situ U-Pb zircon geochronology显示文摘 | Jackson S E Pearson N J Griffin W L | 2004 | Chemical Geology2004，211，1： | 1 |
| 11 | Safety and efficacy of the extended iliofemoral approach in the treatment of complex fractures of the acetabulum显示文摘 | Griffin D B Beaule P E Matta J M | 2008 | J Bone Joint Surg Br2008，87，10： | 1 |
| 12 | Interleukin-1, neuroflammation, andAlzheimer's disease显示文摘 | Mrak R E Griffin W S | 2001 | Neurobiol Aging2001，22，6： | 1 |
| 13 | Toward atheory of organizational creativity 显示文摘 | Woodman R W Sawyer J E Griffin R W | 1993 | Academy ofManagement Review1993，，18： | 1 |
| 14 | The Hf isotopecompositon of cratonic mantle: LA-MC-ICPMS analysis of zir-con megacrysts in kimberlites显示文摘 | Griffin W L Pearson N J * Belousova E A | 2000 | Geochemica et CosmochimicaActa2000，64，： | 1 |
| 15 | Neoproterozoic re- cycling of the Sveconorwegian orogenic belt: Detrital-zircon data from the Sparagmite basins in the Scandinavian Cale- donides 显示文摘 | Bingen B Belousova E A Griffin W L | 2011 | Precambrian Research2011，189，： | 1 |
| 16 | Foodbome illness ac-quired in the United States - unspecified agents 显示文摘 | Scallan E Griffin PM Aangulo FJ | 2011 | Emerg In-fect Dis2011，17，1： | 1 |
| 17 | Toward a theory of organizational creativity显示文摘 | WOODMAN R W SAWYER J E GRIFFIN R W | 1993 | Academy of Man- agement Review1993，18，： | 1 |
| 18 | Sensitivity of tuned bladed disk response to frequency veering显示文摘 | Kenyon J A Griffin J H Kim N E | 2005 | Journal of Engineering for Gas Turbines and Power2005，127，4： | 1 |
| 19 | Zircon chemistry andmagma mixing, SE China: In-situ analysis of Hf isotopes,Tonglu and Pingtan igneous complexes显示文摘 | Griffin W L Wang X Jackson S E | 2002 | Lithos2002，61，34： | 1 |
| 20 | The application of Ia- set ablation-inductively coupled plasma-mass spectrometry to in si- tu U-Pb zircon geochronology显示文摘 | Jackson S E Pearson N J Griffin W L | 2004 | Chemical Geology2004，211，： | 1 |
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