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| 1 | 22-gauge core vs 22-gauge aspiration needle for endoscopic ultrasound-guided sampling of abdominal masses显示文摘AIM To compare the aspiration needle(AN) and core biopsy needle(PC) in endoscopic ultrasound-guided fine needle aspiration(EUS-FNA) of abdominal masses.METHODS Consecutive patients referred for EUS-FNA were included in this prospective single-center trial. Each patient underwent a puncture of the lesion with both standard 22-gauge(G) AN(Echo Tip Ultra; Cook Medical, Bloomington, Indiana, United States) and the novel 22 G PC(Echo Tip Pro Core; Cook Medical, Bloomington, Indiana, United States) in a randomized fashion; histology was attempted in the PC group only. The main study endpoint was the overall diagnostic accuracy, including the contribution of histology to the final diagnosis. Secondary outcome measures included material adequacy, number of needle passes, and complications.RESULTS Fifty six consecutive patients(29 men; mean age 68 years) with pancreatic lesions(n = 38), lymphadenopathy(n = 13), submucosal tumors(n = 4), or others lesions(n = 1) underwent EUS-FNA using both of the needles in a randomized order. AN and PC reached similar overall results for diagnostic accuracy(AN: 88.9 vs PC: 96.1, P = 0.25), specimen adequacy(AN: 96.4% vs PC: 91.1%, P = 0.38), mean number of passes(AN: 1.5 vs PC: 1.7, P = 0.14), mean cellularity score(AN: 1.7 vs PC: 1.1, P = 0.058), and complications(none). A diagnosis on the basis of histology was achieved in the PC group in 36(64.3%) patients, and in 2 of those as the sole modality. In patients with available histology the mean cellularity score was higher for AN(AN: 1.7 vs PC: 1.0, P = 0.034); no other differences were of statistical significance.CONCLUSION Both needles achieved high overall diagnostic yields and similar performance characteristics for cytological diagnosis; histological analysis was only possible in 2/3 of cases with the new needle. | William Sterlacci Athanasios D Sioulas Lothar Veits Pervin G?nüllü Guido Schachschal Stefan Groth Mario Anders Christos K Kontos Theodoros Topalidis Andrea Hinsch Michael Vieth Thomas R?sch Ulrike W Denzer | 2016 | World Journal of Gastroenterology2016，22，39： | 2 |
| 2 | Randomized phase Ⅱ trialgemcitabine-cisplatin with or without trastuzumab in HER- 2-positive non-small-cell lung cancer显示文摘 | Gatzemeier U Groth G Butts C | 2004 | Ann Onco2004，15，1： | 1 |
| 3 | Reorganization of substratum-bound fibronectin on hydrophilic and hydrophobic materials is related to biocompatibility显示文摘 | ALTANKOV G GROTH T | 1994 | J Mater Med1994，5，910： | 1 |
| 4 | High-level expression of the Arabidopsis thdiana ethylene receptor protein ETR1 in Escherichia coli and purification of the recombinant protein显示文摘 | Voet-van-Vormizeele J Groth G | 2003 | Protein Expression and Purification2003，32，1： | 1 |
| 5 | Arou- sing sleeping genes: shifts in secondary metabolism of metal tolerant actinobacteria under conditions of heavy metal stres显示文摘 | HAFERBURG G GROTH I KOTHE E | 2009 | Biometals2009，，22： | 1 |
| 6 | Assessment of myocardial viability in ischemic heart disease by cardiac magnetic resonance imaging显示文摘 | Muellerleile K Barmeyer A Groth M Lund G K | 2008 | Minerva Cardioangiol2008，56，： | 1 |
| 7 | Customer reactions to emotional labor: The roles of employee acting strategies and customer detection accuracy 显示文摘 | Groth M Hennig-Thurau T Walsh G | 2009 | Academy of Management Journal2009，52，5： | 1 |
| 8 | Reorganization of substratum-bound fibronectin on hydrophilic and hydrophobic materials is related to biocompatibility显示文摘 | Altankov G Groth T | 1994 | J Mater Sci Mater Med1994，5，： | 1 |
| 9 | 查看详情显示文摘 | Bellinger K C G Kempner E Groth D F | | 0，，： | 1 |
| 10 | Effect of sorbate planarity on environmental black carbon sorption显示文摘 | Cornelissen G Elmquist M Groth I | 2004 | Environ Sci Technol2004，38，13： | 1 |
| 11 | New linked macrocyclic systems derived from selectively protected S2 N2 macrocycles 显示文摘 | GROTH A M LINDOY L F MEEHAN G V | 1996 | J Chem Soc Perkin Trans1996，1，13： | 1 |
| 12 | Sirolimus (rapamy cin)-based therapy in human renal transplantation: similar effi caey and different toxicity compared with eyclosporine显示文摘 | Groth C G Backman L Morales J M | 1999 | Transplantation1999，67，7： | 1 |
| 13 | The effects ofFGF-2 gene therapy combined with voluntary exercise on axonal re-generation across peripheral nerve gaps显示文摘 | Haastert K Ying Z Grothe C Gómez-Pinilla F | 2008 | Neurosci Lett2008，443，3： | 1 |
| 14 | Randomized phase Ⅱ trial of gemcitabine-cisplatin with or without trastuzumab in HER-2-positire non-small-cell lung cancer 显示文摘 | Gatzemeier U Groth G Butts C | 2004 | Ann Oncol2004，15，1： | 1 |
| 15 | Topotecan and etoposide as first-line therapy for extensive disease small cell lung cancer: a phase II trial of a platinum-free regimen显示文摘 | Reck M Groth G Buehholz E | 2005 | Lung Cancer2005，48，3： | 1 |
| 16 | N eurotrophin activation of NFAT - dependent transcription contributes to the regulation of pro - nociceptive genes 显示文摘 | Groth R D Coicou L G Mermelstein P G | 2007 | J N eurochem2007，102，4： | 1 |
| 17 | Port-access coronary artery bypass grafting:technique and comparative results显示文摘 | SUTHERLAND S E BURTON H G | 1999 | Ann Thorac Surg1999，68，： | 1 |
| 18 | VEGF expression by mesenchymal stem cells contributes to angiogenesis in panereatic carcinoma显示文摘 | Beckermann B M Kallifatidis G Groth A | 2008 | British Journal of Cancer2008，99，4： | 1 |
| 19 | Fibroblast spreading and proliferation on hydrophilic and hydrophobic surfaces is related to tyrosine phosphorylation in focal contacts显示文摘 | Groth T Altankov G | | 0，，： | 1 |
| 20 | Structure of the recombinant full-length hamster prion protein PrP(29-231): the N terminus is highly flexible显示文摘 | Viles J H Groth D | 1997 | Proc Natl Acad Sci USA1997，94，13： | 1 |
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