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| 1 | Sedation and safety of propofol for therapeutic endoscopic retrograde cholangiopancreatography显示文摘Endoscopic retrograde cholangiopancrea tography(ERCP) is the most complex gastrointestinal procedure,which needs patients’ cooperation. The aim of this study was to observe the quality and safey of sedation with propofol in patients undergoing therapeutic ERCP. METHODS:Seventy patients who had undergone therapeutic ERCP were randomly divided into two groups.One group, given intravenously propofol, and the other sedated with routine method, served as the control. Blood pressure, heart rate,oxygen saturation were monitored and cardiorespiratory event was observed. Patient cooperation,performance, recovery time and amnesia served as variables postoperation. RESULTS:Blood pressure elevated in four patients in the propofol group, less than in the control group(P<0.01). Seven patients showed decreased blood pressure after administration of propofol,but none in the control group (P<0.01). Twelve patients in the control group showed mild or significant resistance, but none in the propofol group (P<0.01). The time for performance in the propofol group(P<0.05) was shorter than in the control group. Patient recovery was quicker in the propofol group than in the control group (P<0.01). The degree of amnesia better in the propofol group than in the control group ( P<0.01). The degree of amnesia was also better in the propofol group than in the control group (P<0.01). CONCLUSIONS:Propofol proves to be an excellent sedative for therapeutic ERCP. Being effective and safe, it shows a shorter ERCP duration but quick recovery and better amnesia. It is better than other routine sedatives. | Digestive Department (Chen WX, Lin HJ, Gu Q, Zhong XQ, Yu CH, Li YM and Gu ZY) and Department of Intensive Care Unit (Zhang WF), First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003 , China | 2005 | Hepatobiliary & Pancreatic Diseases International2005，4，3： | 10 |
| 2 | Association of nonalcoholic fatty liver disease with type 2 diabetes: clinical features and independent risk factors in diabetic fatty liver patients显示文摘Nonalcoholic fatty liver disease(NAFLD) is a common chronic liver disease in China, of which diabetic fatty liver (DFL) accounts for a large proportion in clinic. DFL is a disease without specific clinical features and lacking of confirmatory laboratory tests, and the etiology of hepatic steatosis remains poorly understood. The aim of this paper was to explore the clinical characteristics and to determine associated risk factors in type 2 diabetes patients with fatty liver. METHODS: A total of 166 patients, 53 in DFL group and 113 in NDFL(diabetes without fatty liver) group participated in this study. Serum fasting blood glucose (FBG), alanine aminotransferase(ALT), aspartate aminotransferase (AST), alkaline phosphate (AKP), gamma glutamyl transpeptidase (GGT), total cholesterol (TC), triglyceride (TG), high density lipoprotein-cholesterol (HDL-C) were measured in both groups. And these variables were analyzed by using Student’ s t test and logistic regression model. RESULTS:A progressive increase in the level of FBG, ALT, AST, AKP, GGT, TG( P<0.05) and a decrease of HDL-C(P<0.01)were observed from DFL group to NDFL group. And there was no statistical difference in the level of TC between the two groups. CONCLUSIONS:Dyslipidemia, dysglycemia and elevation of liver enzyme can be seen more frequently in the DFL patients than in the NDFL patients. The successive escalation of serum ALT and TG levels and the lower HDL-C level are the independent risk factors of DFL. | Department of Digestive Medicine, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China (Jin HB, Gu ZY, Yu CH and Li YM) | 2005 | Hepatobiliary & Pancreatic Diseases International2005，4，3： | 9 |
| 3 | Radiotherapy of double primary esophageal carcinoma显示文摘INTRODUCTIONDouble primary esophageal carcinoma is defined ashaving two loci of squamous cell cancersimultaneously or consecutively developing indifferent sites of esophagus.This rare diseaseappears mostly in the literature as case reports,reports about its treatment are even moreinfrequent.Here we present our experiences | Xiao ZF Yang ZY Zhou ZM Yin WB Gu XZ | 2000 | World Journal of Gastroenterology2000，6，1： | 4 |
| 4 | 环境铅暴露与血压的关系:2003-2010美国健康和营养调查显示文摘在铅暴露逐渐降低的环境下,该文通过分析2003-2010美国健康和营养调查资料,旨在研究血铅与血压、高血压的关系。纳入研究对象12 725人,其中非洲裔21.1%,西语裔20.5%,白人58.4%,女性48.7%。与非非洲裔比较,非洲裔的血压[126.5/71.9比123.9/69.6mm Hg(1mm Hg=0. | Hara A Thijs L Asayama K Gu YM Jacobs L Zhang ZY Liu YP Nawrot TS Staessen JA 刘莉 叶鹏 | 2014 | 中华高血压杂志2014，22，10： | 3 |
| 5 | Clinical effectiveness of the PolyScopeTM endoscope system combined with holmi- um laser lithotripsy in the treatment of upper urinary cal- culi with a diameter of less than 2 cm显示文摘 | Gu SP Huang YT You ZY | 2013 | Exp Ther Med2013，6，2： | 1 |
| 6 | Mechanism of ischemic tolerance induced by hyperbaric oxygen preconditioning involves upregulation of hypoxia-inducible factor-1α and erythropoietin in rats显示文摘 | Gu GJ Li YP Peng ZY | 2008 | J Appl Physiol2008，104，4： | 1 |
| 7 | FXY1)3 expression in gliomas and its clmicopathological significance显示文摘 | Wang MW Gu P Zhang ZY | 2009 | Oncol Res2009，18，4： | 1 |
| 8 | A highly sensitive quantitative bioassay for human interleukin-11 显示文摘 | Lu ZY Zhang XG Gu ZJ | 1994 | J Immunol Methods1994，173，1： | 1 |
| 9 | Prevalence, risk factors and recognition rates of depressive disorders among inpa- tients of tertiary general hospitals in Shanghai, China 显示文摘 | Yan ZY Gu M J Zhong BL | 2013 | J Psychosom Res2013，75，1： | 1 |
| 10 | Improvement of the high-rate discharge properties of LiCo02 with the Ag additives 显示文摘 | Huang SH Wen ZY Yang XL Gu ZH Xu XH | 2005 | J Power Sources2005，148，： | 1 |
| 11 | Time course of expression of bcl-2 and bax in rabbit condylar chondrocytes fol owing forward mandibular positioning显示文摘 | Wu MJ Zhan J Gu ZY | | 0，，03： | 1 |
| 12 | Prevalence, risk factors and recognition rates of depressive disorders among inpatients of tertiary general hospitals in Shanghai, China 显示文摘 | Yan ZY Gu MJ Zhong BL | 2013 | J Psychosom Res2013，75，1： | 1 |
| 13 | Numerical simulation of hemo?dynamics in stented internal carotid aneurysm based on patient?specific mode显示文摘 | Fu WY Gu ZY Meng XL et at | 2010 | J Biomech2010，43，7： | 1 |
| 14 | Effects of hydrostatic pressure on cytoskeleton and BMP-2, TGF-beta, SOX-9 production in rat temporomandibular synovial fibroblasts 显示文摘 | Wu M J Gu ZY Sun W | 2008 | OsteoarthritisCartilage2008，16，1： | 1 |
| 15 | Clinical effectiveness of the Poly-Scope? endoscope system combined with holmium laser lithotripsyin the treatment of upper urinary calculi with a diameter of less than2 cm 显示文摘 | Gu SP Huang YT You ZY | 2013 | Exp Ther Med2013，6，2： | 1 |
| 16 | Childhood pancreatoblastoma:clinical features and immunohistochemistry analysis显示文摘 | Gu WZ Zou CC Zhao ZY | 2008 | Cancer Lett2008，264，1： | 1 |
| 17 | Increased expression of calcium/calmodulin-dependent protein kinase typeⅡsubunit delta after rat traumatic brain injury显示文摘 | Zhang MY Shan HY Gu ZY | 2012 | J Mol Neurosis2012，46，3： | 1 |
| 18 | Type Ⅱ collagen and aggrecan mRNA expression by in situ hybridization in rabbit temporomandibular joint posterior attachment following disc displacement显示文摘 | Gu ZY Feng JY Shibata T | 2003 | Arch Oral Biol2003，48，1： | 1 |
| 19 | Mechanism of ischemic tolerance induced by hyperbaric oxygen preconditioning involves up regulation of hypoxia-inducible factor-1 and erythropoietin in rats显示文摘 | Gu GJ Li YP Peng ZY | | 0，，04： | 1 |
| 20 | Developmefit of a novel cross-streaking method for isolation, confirmation, and enumeration of Salmonella from irrigation ponds显示文摘 | Luo ZY Gu GY Giurcanu MC | 2014 | JMicrobiol Methods2014，101，： | 1 |
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