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| 1 | Leber's hereditary optic neuropathy is associated with the mitochondrial ND4 G11696A mutation in five Chinese families显示文摘 | Zhou XT Wei QP Yang L Tong Y Zhao FX Lu CJ Qian YP Sun YH Lu F Qu J Guan MX | 2006 | 中国生物学文摘2006，20，4： | 18 |
| 2 | Aminoglycoside-induced and non-syndromic hearing loss is associated with the G7444A mutation in the mitochondrial COI/tRNA (Ser(UCN)) genes in two Chinese families显示文摘 | Zhu Y Qian YP Tang XW Wang JD Yang L Liao ZS Li RH Ji JZ Li ZY Chen JF Choo DI Lu JX Guan MX | 2006 | 中国生物学文摘2006，20，4： | 16 |
| 3 | Oxygen and Nitrogen Effects on MC Carbide in K465 Nickel-Base Superalloy显示文摘Effects of oxygen and nitrogen on MC carbide in nickel-base superalloy K465 were investigated, because neither of the two gas elements was found to decide MC carbide morphology monotonically. The morphology of MC carbide under alloy solidified in conventional investment casting condition was observed to transform from script-type to block-type with the total oxygen and nitrogen content (gas content) in samples rising up from 1.2×10-6 mol/g to 2.6×10-6 mol/g. The area fraction and composition of the MC carbide also varied with increase of gas content. However, the morphology of MC carbide kept to be script-type even when gas content was up to 3.4×10-6 mol/g in samples solidified with a much higher cooling rate. These results indicate that effects of gas content on formation of MC carbide can be observed in specimens solidified with low cooling rate, but such changes in MC carbide cannot be found when the cooling rate is high. | Wang L N Zheng Q Sun X F Guan H R Hu Z Q | 2009 | 稀有金属材料与工程2009，38，A03： | 4 |
| 4 | Influence of Fe Addition on Products of Self-Propagating High-Temperature Synthesis Reaction in 3Ti-Si-2C System显示文摘Influence of Fe addition on products of self-propagating high-temperature synthesis (SHS) reaction in 3Ti-Si-2C system was investigated in the present study. Without Fe addition, Ti5Si3 and TiC are the dominant phases along with a small amount of Ti3SiC2 phase and unreacted C left in the final products. As Fe content ranges from 10% to 30%, the products consist of TiC, Ti5Si3, Fe2Ti and unreacted C, but no trace of Ti3SiC2 phase is detected. Furthermore, the amounts of both Fe2Ti and C phases increase with Fe content increasing. Addition of Fe has a great effect on the reaction route and significantly restrains the formation of Ti3SiC2 during the combustion synthesis process, and therefore, the SHS is not an effective fabrication technique to synthesize the ternary Ti3SiC2 ceramic in either 3Ti-Si-2C or Fe-3Ti-Si-2C system. Besides, without Fe addition, Ti5Si3 presents as the coarse irregular appearance with an obviously sintered morphology. In contrast, the shape of Ti5Si3 exhibits more and more spherical (cobblestone-like) and the surface becomes increasingly smooth, because the amount of liquids formed during the SHS reaction increases with the increase of Fe content. On the other hand, with Fe content increasing from 0 to 30 wt.%, the particulate size of TiC decreases from more than 5 μm to 1 μm or less, mainly due to the fact that the combustion temperature decreases with the increase of Fe content in the preforms. | Guan Q L Wang H Y Li S L Si W P Jiang Q C | 2009 | 稀有金属材料与工程2009，38，A03： | 2 |
| 5 | Development of a unified viscoplasticity constitutive model based on classical plasticity theory显示文摘The traditional unified viscoplasticity constitutive model can be only applied to metal materials.The study of the unified constitutive theory for metal materials has discovered the correlation between the classical plasticity theory and the unified viscoplasticity constitutive model,thus leading to the con-cepts of the classic plastic potential and yield surface in the unified constitutive model.Moreover,this research has given the continuous expression of the classical plastic multiplier and presented the corresponding constructive method,which extends its physical significance and lays down a good foundation for the application of the unified constitutive theory to the material analysis in more fields.This paper also introduces the unified constitutive model for metal materials and geo-materials.The numerical simulation indicates that the construction should be both reasonable and practical. | GUAN Ping LIU ChangChun Lü HeXiang | 2009 | Science China(Technological Sciences)2009，52，5： | 2 |
| 6 | A unified viscoplasticity constitutive model based on irreversible thermodynamics显示文摘A unified viscoplasticity constitutive model for metal materials is developed within the framework of irreversible thermodynamics, and an expression for the Helmholtz free energy function involving the parameters reflecting kinematic hardening and isotropic hardening is given. At the same time a non-associated flow potential function including the corresponding state variables is also given, from which the flow equation and the evolution equations of the internal state variables are derived. Thus, a general theoretical framework constructing a unified viscoplasticity constitutive model is given. Compared with the typical unified viscoplasticity constitutive models, the presented model evidently satisfies the irreversible thermodynamics laws. Moreover, this method not only provides a new theoretical foundation for further development of the unified viscoplasticity constitutive model, but also gives a new theoretical framework for the stress-strain analysis of more materials. | LIU ChangChun Lü HeXiang GUAN Ping | 2008 | Science China(Technological Sciences)2008，51，4： | 2 |
| 7 | 选择性头部降温对胎羊缺血性脑损伤纹状体神经元凋亡和星形胶质细胞增殖的影响显示文摘目的研究选择性头部降温对缺血性脑损伤胎羊纹状体神经元凋亡和星形胶质细胞增殖的影响。方法胎羊于妊娠117~124d时通过双侧颈动脉阻塞30min造成双侧脑缺血损伤,损伤后将胎羊随机分为:损伤组(n=10)、2h低温组(损伤后2h开始亚低温治疗,n=7)和6h低温组(损伤后6h开始亚低温治疗,n=8),另设正常对照组(n=5)。通过冷循环水进行选择性头部降温,取脑组织用免疫组化法检测胎羊纹状体caspase-3(半胱天冬氨酸酶-3),GFAP(胶质纤维酸性蛋白)和PCNA(增殖细胞核抗原)的表达。结果①纹状体神经元凋亡:正常对照组中,caspase-3表达极少(11.00±13.77),损伤组caspase-3免疫阳性细胞为177.70±48.69,明显增加(P=0.000),损伤后2h治疗组(54.14±39.44,P=0.000)和损伤后6h治疗组(122.43±52.36,P=0.017)均能减少caspase-3免疫阳性细胞。②纹状体星形胶质细胞增殖:与正常对照组(163.40±21.98)相比,缺血性脑损伤组的GFAP免疫阳性细胞明显增多(433.25±66.69,P=0.000),损伤后2h开始亚低温治疗(219.50±35.31,P=0.000)和损伤后6h开始亚低温治疗(272.50±86.20,P=0.000)均能减少GFAP免疫阳性细胞。③纹状体PCNA阳性细胞的表达:在正常对照组中,PCNA免疫阳性细胞较少,为153.40±12.46,缺血性脑损伤组的PCNA免疫阳性细胞明显增多(353.70±45.60,P=0.000),损伤后2h开始亚低温治疗(187.14±26.26,P=0.000)和损伤后6h开始亚低温治疗(230.25±67.46,P=0.000)均能减少PCNA免疫阳性细胞。结论亚低温可以抑制纹状体神经元的凋亡和星形胶质细胞的增殖,该作用可能为选择性头部降温的脑保护作用机制之一。 | 骆菲 曹云 Guan J Gunn AJ Bennet L George S Gluckman PD 杨毅 陈莲 | 2007 | 复旦学报(医学版)2007，34，4： | 2 |
| 8 | Performance of Asynchronous MC2CDMA Systems with Maximal Ratio Combining in Frequency2selective Fading Channels显示文摘 | K ZHANG Y L GUAN | 2004 | EURASIP Journal on Applied Signal Processing2004，，： | 1 |
| 9 | Chemotherapy using 5-fluorouracil and nitrocaphanum in malignant trophoblastic tumor显示文摘 | Wang Y Jiu L Guan Y | 1998 | Gynecol Oncol1998，71，3： | 1 |
| 10 | Multipotential mesenchymal stem cells from femoral bone marrow near the site of osteonecrosis显示文摘 | Guan H Hongsen C | 2001 | J Dent Res2001，80，： | 1 |
| 11 | Mesoporous CaO-ZrO2 nano-oxides: a novel solid base with high activity and stability 显示文摘 | LIU S G MA J GUAN L X | 2009 | Mieroporous and Mesoporous Materials2009，117，： | 1 |
| 12 | Surface design by natural splines over refined grid points 显示文摘 | GUAN L T LIU B | 2004 | J Comp Anal and Appl2004，163，1： | 1 |
| 13 | Superior efficacy of a Cremophor-fiee albumin-bound paclitaxel compared with solvent-based paclitaxel in Chinese patients with metastatic breast cancer显示文摘 | GUAN Z Z LI Q L FENG F Y | 2009 | Asian Pac J Clia Oncol2009，5，3： | 1 |
| 14 | Preparation of a novel mesoporous solid base Na-ZrO2 with ultra high thermalstability显示文摘 | Liu S G Huang S Y Guan L X | 2007 | Microporous and Mesoporous Materials2007，102，： | 1 |
| 15 | Characterization and degradation behavior of AZ31 alloy surface modified by bone-like hydroxyapatite for implant applications显示文摘 | Wen C L Guan S K Peng L et at | 2009 | Applied Surface Science2009，255，1314： | 1 |
| 16 | Interconnecting bilayer networks显示文摘 | Xu X L Qu Y Q Guan S | 2011 | Europhy Lett2011，93，68： | 1 |
| 17 | N-Palmitoylethanolamide derivatives : synthesis and studies on anticonvulsant and antidepressant activities显示文摘 | Guan L Sui X Deng X Q | 2011 | Medicinal Chemistry Research2011，20，5： | 1 |
| 18 | Delay-dependent Guaranteed Cost Control for T-S Fuzzy Systems with Time Delays显示文摘 | Guan X P Chen C L | 2004 | IEEE Trans on Fuzzy Systems2004，12，2： | 1 |
| 19 | Multitangent-plane surface method for reliability calculation显示文摘 | Guan X L Melchers R E | 1997 | J Eng Mech1997，123，10： | 1 |
| 20 | Effect of enamel coating on oxidation and hot corrosion resistance of Ti-24Al-14Nb-3V显示文摘 | GUAN C H TANG Z L WANG F H WU W T | 2000 | Chinese J Mater Res2000，14，： | 1 |
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