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| 1 | Improvement of quantitative testing of liver function in patients with chronic hepatitis C after installment of antiviral therapy显示文摘AIM: To investigate if and to what extent antiviral therapy influenced a broad panel of quantitative testing of liver function (QTLF).METHODS: Fifty patients with chronic hepatitis C were either treated with interferon (n = 8), interferon/ribavirin (n = 19) or peg-interferon/ribavirin (n = 23). Quantitative testing of liver function, including aminopyrine breath test (ABT), galactose elimination capacity (GEC), sorbitol clearance (SCI) and indocyanine green clearance (ICG)was performed before and 3 mo after initiation of antiviral therapy.RESULTS: After 3 mo of antiviral treatment, 36 patients showed normal transaminases and were negative for HCV-RNA, 14 patients did not respond to therapy. ABT and GEC as parameters of microsomal and cytosolic liver function were reduced in all patients before therapy initiation and returned to normal values in the 36 therapy responders after 3 mo. Parameters of liver perfusion (SCI and ICG) were not affected by antiviral therapy. In the 14 non-responders,no changes in QTLF values were observed during the treatment period.CONCLUSION: ICG and SCI remained unaffected in patients with chronic hepatitis C, while ABT and GEC were significantly compromised. ABT and GEC normalized in responders to antiviral therapy. Early determination of ABT and GEC may differentiate responders from non-responders to antivJral treatment in hepatitis C. | Matthias Ocker Marion Ganslmayer Steffen Zopf Susanne Gahr Christopher Janson Eckhart G. Hahn Christoph Herold | 2005 | World Journal of Gastroenterology2005，11，35： | 8 |
| 2 | Autoantibodies to glutamate receptor GIuR3 in Rasmussen's encephalitis 显示文摘 | Rogers SW Andrews PI Gahring LC | 1994 | Science1994，265，5172： | 1 |
| 3 | Tongue rolling and tongue folding显示文摘 | Gahres E E | 1952 | Journal of Heredity1952，43，： | 1 |
| 4 | Successful treat-ment of major depression with electroconvulsive therapy in apregnant patient with previous non-response to prefrontal rTMS显示文摘 | Gahr M Blacha C Connemann BJ | 2012 | Pharmacopsychiatry2012，45，2： | 1 |
| 5 | Pregabalin abuse and dependence in Germany:results from a database query显示文摘 | Gahr M Freudenmann R W Hiemke C | 2013 | European Journal of Clinical Pharmacology2013，69，6： | 1 |
| 6 | Effect of grain size on friction and sliding wear of oxide ceramics 显示文摘 | Zum Gahr K - H Bundschuh W Zimmerlin B | 1993 | Wear1993，，： | 1 |
| 7 | Surface Modification of Ceramics for Improved Tribological Properties显示文摘 | Zum Gahr K H Schneider J | 2000 | Ceramics International2000，26，4： | 1 |
| 8 | Effect of grain size on friction and sliding wear of oxide ceramics 显示文摘 | K H Zum Gahr W Bundsehuh B Zimmerlin | 1993 | Wear1993，，： | 1 |
| 9 | Characterization of a new BAC library for rainbow trout:evidence for multi - locus dupli- cation显示文摘 | PALTI Y GAHR S A HANSEN J-D | 2004 | Anita Genet2004，35，2： | 1 |
| 10 | Effect of grain size on friction and sliding wear of oxide ceramics显示文摘 | Zum K H Gahr Bundschuh W Zimmerlin B | 1993 | Wear1993，，： | 1 |
| 11 | Influence of porosity on friction and sliding wear of TZP-zirconia 显示文摘 | W Bundschuh K H Zum Gahr | 1991 | Wear of Materials1991，1，： | 1 |
| 12 | Optimizing fracture toughness and abrasion resistance in white cast irons显示文摘 | Karl-Heinz Zum Gahr Douglas V. Doane | 1980 | Metallurgical Transactions A1980，，4： | 1 |
| 13 | Pro-inflammatory cytokines modify neuronal nicotinic acetylcholine receptor assembly显示文摘 | Gahring LC Days EL Kaasch T | 2005 | J Neuroimmunol2005，166，12： | 1 |
| 14 | Characterization of rainbow trout myostatin-2 genes (rtMSTN-2a and -2b): genomic organization, differential expression, and pseudogenization 显示文摘 | Garikipati D K Gahr S A Roalson E H | 2007 | Endocrinology2007，148，5： | 1 |
| 15 | Diffusion-weighted MRI for differentiation of neuroblastoma and ganglioneuroblastomal ganglioneuroma显示文摘 | Gahr N Darge K Hahn G | 2011 | EurJ Radiol2011，79，3： | 1 |
| 16 | Tumor necrosis factor alpha enhances nicotinic receptor up-regulation via a p38MAPK-dependent pathway显示文摘 | Gahring LC Osborne-Hereford AV Vasquez-Opazo GA | 2008 | J Biol Chem2008，283，2： | 1 |
| 17 | Tongue roiling and tongue folding显示文摘 | Gahres E E | 1952 | Journal of Heredity1952，43，： | 1 |
| 18 | Embryonic expression of UCP2 in rainbow trout (Oncorhynchus mykiss ) 显示文摘 | Coulibaly I Gahr S A Yao J | 2006 | Fish Physiol Biochem2006，32，： | 1 |
| 19 | IGF-I,IGF-II,and IGF-receptor-1 transcript and IGF-II protein expression in Myostatin knockout mice tissues显示文摘 | Kocamis H Gahr S A Batelli L | 2002 | Muscle Nerve2002，26，1： | 1 |
| 20 | How microstructure affect abrasive wear resistance显示文摘 | Karl-Heinz Zum Gahr | 1979 | Metal Progress1979，，9： | 1 |
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