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| 1 | Metabolic syndrome attenuates ulcerative colitis: Correlation with interleukin-10 and galectin-3 expression显示文摘BACKGROUND Ulcerative colitis(UC)is a chronic disease characterized by inflammation of intestinal epithelium,primarily of the colon.An increasing prevalence of metabolic syndrome(MetS)in patients with UC has been documented recently.Still,there is no evidence that MetS alters the course of the UC.AIM To test the influence of the MetS on the severity of UC and the local and systemic immune status.METHODS Eighty nine patients with de novo histologically confirmed UC were divided in two groups,according to ATP III criteria:Group without MetS(no MetS)and group with MetS.RESULTS Clinically and histologically milder disease with higher serum level of immunosuppressive cytokine interleukin-10(IL-10)and fecal content of Galectin-3(Gal-3)was observed in subjects with UC and MetS,compared to subjects suffering from UC only.This was accompanied with predomination of IL-10 over pro-inflammatory cytokines tumor necrosis factorα(TNF-α),interleukin-6(IL-6),and interleukin-17(IL-17)in the sera as well as Gal-3 over TNF-αand IL-17 in feces of UC patients with MetS.Further,the patients with both conditions(UC and MetS)had higher percentage of IL-10 producing and Gal-3 expressing innate and acquired immune cells in lamina propria.CONCLUSION Local dominance of Gal-3 and IL-10 over pro-inflammatory mediators in patients with MetS may present a mechanism for limiting the inflammatory process and subsequent tissue damage in UC. | Marina Jovanovic Bojana Simovic Markovic Nevena Gajovic Milena Jurisevic Aleksandar Djukic Ivan Jovanovic Nebojsa Arsenijevic Aleksandra Lukic Natasa Zdravkovic | 2019 | World Journal of Gastroenterology2019，25，43： | 5 |
| 2 | Epstein-Barvirus hepatitisassociated with icterus-a case report显示文摘 | Canovic P Gajovic O Todorovic Z | 2006 | Med Pregl2006，59，3： | 1 |
| 3 | Mild spherocytic hereditary elliptocytosis and altered levels of and α- and γ-adducins in β-adducin-deficient mice显示文摘 | Muro AF Marro ML Gajovic S | 2000 | Blood2000，95，： | 1 |
| 4 | Mechanochemical preparationof nanocrystalline TiO2 powders and their behavior at high tempera lures显示文摘 | Gajovic A Furic K Tomaaic N | 2005 | J Alloys Compd2005，398，12： | 1 |
| 5 | Distribution, differentiat- ion, and survival of intravenously administered neural stem ce- lls in a rat model of amyotrophic lateral sclerosis显示文摘 | Mitrecic D Nicaise C Gajovic S | 2010 | Cell Transp- lant2010，19，5： | 1 |
| 6 | Regulated splicing of the fibronectin EDA exon is essential for proper skin wound healing and normal lifespan显示文摘 | Muro AF Chauhan AK Gajovic S et at | 2003 | J Cell Biol2003，162，1： | 1 |
| 7 | Genes expressed after retinoic acid-mediated differentiation of embryoid bodies are likely to be expressed during embryo development显示文摘 | Gajovic S Chowdhury K Gruss P | 1998 | Exp Cell Res1998，242，： | 1 |
| 8 | New enzyme sensors for morphine and codeine based on morphine dehydrogenase and laccase显示文摘 | Bauer C G Kuehn A Gajovic N | 1999 | Fresenius''J Anal Chem1999，364，： | 1 |
| 9 | Structure of sodi- um phosphate glasses containing A1203 and/or Fe203, Part I 显示文摘 | Milankovic A M Gajovic A Santic A et at | 2001 | J Non-Cryst Solids2001，289，13： | 1 |
| 10 | Incidence,risk factors and outcome of nosocomial pneumonia in patients with central nervous system infections显示文摘 | Gajovic Olgica Todorovic Zoran Mijailovic Zeljko | 2011 | Srpski Arhiv za Celokupno Lekarstvo2011，139，7： | 1 |
| 11 | Operation of a Miniature Redox Hydrogel-Based Pyruvate Sensor in Undiluted Deoxygenated Calf Serum显示文摘 | Gajovic N Binyamin G Axel W | 2000 | Analytical Chemistry2000，72，13： | 1 |
| 12 | Spectral response of amorphous-nano-crystalline silicon thin films显示文摘 | Gracin D Gajovic A Juraic K | 2008 | Journal of Non-Crystalline Solids2008，354，： | 1 |
| 13 | Molecular biomarkers of lung carcinoma显示文摘 | Vrabec BB Gajovic S | 2012 | Front Biosci (Elite Ed)2012，4，86： | 1 |
| 14 | New enzyme sensors for morphine and codeine based on morphine dehydrogenase and laccase 显示文摘 | BAUCER C G KUHN A GAJOVIC N | 1999 | Fresenius J Anal Chem1999，364，12： | 1 |
| 15 | Morphological features of tail bud development in truncate mouse mutants显示文摘 | Kostovic-Knezevic L Gajovic S | 2004 | Cells tissues organs2004，178，1： | 1 |
| 16 | Hospital infections in a neurological intensive care unit:incidence,causative agents and risk factors显示文摘 | Djordjevic Z Jankovic S Gajovic O et a/ | 2012 | J Infect Dev Ctries2012，6，11： | 1 |
| 17 | High temperature Raman specaoscopy of titanate nanotubes显示文摘 | Gajovic A Friscic I Plodinec M | 2009 | Journal of Molecular Structure2009，，： | 1 |
| 18 | Identifying a common origin of toner printed counterfeit banknotes by micro-Raman spectroscopy显示文摘 | Bozicevic M S Gajovic A Zjakic I | 2012 | Forensic Science International2012，223，13： | 1 |
| 19 | Regulated splicing of the fibronectin EDA exon is essential for proper skin wound healing and normal lifespan显示文摘 | Muro AF Chauhan AK Gajovic S | 2003 | J Cell Biol2003，162，1： | 1 |
| 20 | Porous zirconium titan-ate ceramics synthesized by sol-gel process 显示文摘 | Macan J Gajovic A H Ivankovic | 2009 | Journal of theEuropean Ceramic Society2009，294，： | 1 |
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