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191篇 您的检索式:作者名="Ganju"
    题名 作者 年代 出处 被引量
1Effect of modulation of unfolded protein response pathway on dengue virus infection显示文摘展开的蛋白质反应(UPR ) 是帮助在紧张的条件下面恢复细胞的动态平衡的事件的串联。什么时候在蛋白质负担和 endoplasmic 蜂窝胃的蛋白质合拢能力有不平衡,被激活(嗯) 由于 na 的增加 ? ve,展开,或房间的错误褶层蛋白质内容。登革热病毒(DENV ) 利用宿主机械综合病毒的蛋白质并且在细胞复制。在 DENV 感染期间,病毒的蛋白质的起来规定增加房间的蛋白质水池,导致 UPR 小径的正式就职。在这研究,我们试着在人的 monocytic 房间理解在 DENV 感染期间感应的 UPR 的后果。完成这个目的,我们使用了 VER-155008 (VER ) , 78 kDa 的一个已知的禁止者调整葡萄糖的蛋白质(GRP78 ) ,它是 UPR 小径的主人管理者。在 VER 处理以后,房间感染 UPR 元素的 DENV,和正式就职,他们的下游的激活被西方的弄污和 RT-PCR 分析学习。有趣地,经由 VER 处理的 GRP78 的抑制通过 UPR 元素的激活导致了 DENV 信封蛋白质的减少的表示,蛋白质象kinase一样嗯居民 kinase ,激活抄写因素 6 ,并且要求肌醇的酶 1 ( IRE1 ),然后导致了象 双stranded 那样的天生的有免疫力的因素的激活 激活RNA 的蛋白质 kinase ( PKR ),干扰素调整了因素 3 ( IRF3 ),原子 factor-B ( NF-B )和 interleukin 1 ( IL-1 )。这策略可以被用来减少病毒的感染短暂地。因此 UPR 元素能是为减少的 DENV 增加的重要治疗学的目标。Drishya Diwaker Kamla Prasad Mishra Lilly Ganju 2015Acta Biochimica et Biophysica Sinica2015,47,12:2
2FuladiCardiopulmonary Exercise Testing in Evaluation of Patients of Chronic Obstructive Pulmonary Disease显示文摘Ganju AA Fuladi AB 2011Indian J Chest Dis Allied Sci2011,53,:1
3The a-chemokine, stromal cell-derived fac- tor-la, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduc- tion pathways显示文摘Ganju R K Brubaker S A Meyer J Dutt P Yang Y Qin S 1998J Biol Chem1998,273,23:1
4Oxygen free radicalinjury is sufficient to cause some Alzheimer-type molecularabnormalities in human CNS neuronal cells显示文摘de la Monte SM Ganju N Feroz N 2000J Alzheimers Dis2000,2,:1
5Systematic design and testing of nested (RT-)PCR primers for specific amplification of mouse rearranged/expressed immunoglobulin variable region genes from small number of B eells显示文摘Rohatgi S Ganju P Sehgal D 2008J Immunol Methods2008,339,2:1
6Transforaminal lumbar interbody fusion:surgical technique and results in 24 patients显示文摘Salehi SA Tawk R Ganju A 2004Neurosurgery2004,54,2:1
7Protein-losing enteropathy in systemic lupus erythematosus显示文摘Edmunds SE Ganju V Beveridge BR 1988Aust N Z J Med1988,18,:1
8Beta-chemokine receptor CCR5 signals via the novel tyrosine kinase RAFTK显示文摘Ganju RK Dutt P Wu L 1998Blood1998,91,3:1
9Transforaminal lumbar inter- body fusion: surgical technique and results in 24 patients显示文摘Salehi S A Tawk R Ganju A 2004Neu- rosurgery2004,54,2:1
10Transforaminal lumbar interbody fusion: surgical technique results in 24 patients显示文摘Salehi SA Tawk R Ganju A 2004Neurosurgery2004,54,2:1
11Bc1-2 predictive markers for breast cancer neoadjuvant chemotherapy显示文摘Syed S Rogers PA Ganju V 2007ANZJ Surg2007,77,9:1
12SHP2 and ch1 participate in alpha-chemokine receptor CXCR4-mediated signaling pathways显示文摘Chernock R D Cherla R P Ganju R K 2001Blood2001,97,3:1
13Anti-inflammatory activity of Seabuckthorn(Hippophae rhamnoides)leaves显示文摘Ganju L Padwad Y Singh R 2005International Immunopharmacology2005,5,12:1
14Slit2-Robo4 pathway mod- ulates lipopolysaccharide - induced endothelial inflammation and its expression is dysregulated during endotoxemia显示文摘ZHAO H ANAND AR GANJU RK 2014J Im- munol2014,192,1:1
15transforaminal lumbar interbody fusion:surgical technique and results in 24patients显示文摘Salehi SA Tawk R Ganju A 2004Neurosurgerv2004,54,2:1
16Primary Intramedullary Tumors of the Spinal Cord 显示文摘Han'op JS Ganju A Groff M 2009Spine2009,34,:1
17MHSIP mental health report card: a consumer-oriented approach to monitoring the quality of mental health plans显示文摘Teague GB Ganju V Hornik JA 1997Eval Rev1997,21,3:1
18Transforaminal lumbar interbody fusion: surgical technique and results in 24 pa- tients显示文摘Salehi SA Tawk R Ganju A 2004Neurosurgery2004,54,2:1
19The alpha-hemokine,stromal cell-derived factor-1 alpha,binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathways显示文摘Ganju RK Brubaker SA Meyer J 1998J Biol Chem1998,273,23:1
20Signal Transduction inhuman Hematopoietic Cells by Vascular Endothelial Growth Factor Related Protein,a Novel Ligand for the FLT4 Receptor显示文摘Wang J F Ganju R K Liu Z Y 1997Blood1997,90,9:1
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