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	题名	作者	年代	出处	被引量
1	Cyclooxygenase-2 polymorphisms and the risk of esophageal adeno-or squamous cell carcinoma显示文摘AIM:To determine whether-1195 A→G and/or-765 G→C polymorphisms in Cyclooxygenase-2(COX-2 ) may have a risk modifying effect on the development of esophageal carcinoma in a Dutch Caucasian population.METHODS:Two study groups were recruited, 252 patients with esophageal carcinoma and 240 healthy controls, matched for race, age, gender and recruiting area.DNA was isolated from whole blood and used for genotyping.PCR products were digested with restriction enzymes and products were analyzed by agarose gel electrophoresis.Odds ratios(OR) and 95% confldence intervals(CI) were estimated.RESULTS:The distribution of the-1195 A→G polymorphism was signif icantly different in esophageal cancer patients compared to controls.The-1195 GG genotype resulted in a higher risk of developing esophageal adenocarcinoma(OR = 3.85, 95% CI:1.45-10.3) compared with the-1195 AA genotype as a reference.The-765 G→C genotype distribution was not different between the two groups.The GG/ GG haplotype was present more often in esophageal adenocarcinoma patients than in controls(OR = 3.45, 95% CI:1.24-9.58;with AG/AG as a reference).The same trends were observed in patients with squamous cell carcinomas, however, the results did not reach statistical signif icance.CONCLUSION:Presence of the COX-2-1195 GG genotype and of the GG/GG haplotype may result in a higher risk of developing esophageal carcinoma.	Jón O Kristinsson Paul van Westerveld Rene HM te Morsche Hennie MJ Roelofs T Wobbes Ben JM Witteman Adriaan CITL Tan Martijn GH van Oijen Jan BMJ Jansen Wilbert HM Peters	2009	World Journal of Gastroenterology2009，15，28：	11
2	Arthroseopie assessment of the medial collateral ligament complex of the elbow 显示文摘	Field LD Callaway GH O'Brien SJ	1995	Am Sports Med1995，4，：	1
3	Genetic markers: progress and potential for cardiovascular disease显示文摘	Gibbons GH Liew C C Goodarzi M O	2004	Grculation2004，109，251：	1
4	Mandibular distraction force: laboratory data and clinical correlation 显示文摘	Robinson RC O'Neal PJ Robinson GH	2001	J Oral Maxillofac Surg2001，59，5：	1
5	Uric acid and the development of hypertension: the normative aging study显示文摘	Perlstein TS Gumieniak O Williams GH	2006	Hypertension2006，48，6：	1
6	Anterior Iliac Crest Bone Graft Harvesting Using the Corticocancellous Reamer System 显示文摘	Westrich GH Geller DS O'Malley MJ	2001	J Orthop Trauma2001，15，7：	1
7	Muhipotent adult germline stem cells and embryonic stem cells functional proteomics revealed an important role of eukaryotic initiation factor 5A (elF5 a)in stem cell differentiation 显示文摘	Dihazi H Dihazi GH Jahn O	2011	J Proteome Res2011，10，4：	1
8	Cloning and characterization of ZNF 189, a novel human Kruppel-like zinc finger gene localized to chromosome 9q22-q31 显示文摘	Odeberg J Rosok O Gudmundsson GH	1998	Genomics1998，50，2：	1
9	LOXL4 as a selective molecular marker in primary and metastatic head/neck carcinoma显示文摘	Scola N G(o)r(o)gh T		0，，11：	1
10	The pharmacology of the veratrum alkaloids 显示文摘	Krayer O Acheson GH	1946	J Pharmacol and Exper Therap1946，86，：	1
11	Association of a promoter polymorphism of the CD14 gene and atopy显示文摘	koppelman GH Reijmerink NE Colin Stine O	2001	Am J Respir Crit Care med2001，163，：	1
12	Vitamin D metabolites and analogs induce lipoxygenase mRNA expression and activity as well as reactive oxygen species (ROS) production in human bone cell line显示文摘	Somjen D Katzburg S Grafi-Cohen M Knoll E Sharon O Posner GH	2011	J Steroid Biochem Mol Biol2011，123，12：	1
13	Uric acid and the development of hypertension: the normative aging study 显示文摘	Perlstein TS Gumieniak O Williams GH	2006	Hypertension2006，48，6：	1
14	Vitamin D analogs induce lipoxygenase mRNA expression and activity as well as reactive oxygen species (ROS) production in human bone cells显示文摘	Somjen D Katzburg S Knoll E Sharon O Posner GH Stern N	2010	J Steroid Biochem Mol Biol2010，121，12：	1
15	Psoriasis is as- sociated with clinically significant cardiovascular risk: A danish nationwide cohort study显示文摘	Ahlehoff O Gislason GH Charlot M	2011	J Intern Med2011，270，2：	1
16	Uric acid and the development of hypertension: the Normative Aging Study显示文摘	Perlstein TS Gumieniak O Williams GH	2006	Hypertension2006，48，6：	1
17	Uric acid and the development of hypertension:the normative aging study显示文摘	Perlstein TS Gumieniak O Williams GH	2006	Hypertension2006，48，6：	1
18	Does laparoscopic ureterolithotomy replace shock-waveithotripsy or ureteroscopy for ureteral stones显示文摘	ROFEIM O YOHANNES P BADLANI GH	2001	Endourol2001，15，3：	1
19	Uric acid and the development of hypertension : the normative aging study 显示文摘	Perlstein TS Gumieniak O Williams GH	2006	Hyper- tension2006，48，6：	1
20	Prognostic signif- icance of vascular endothelial growth factor expression in hu- man ovarian carcinoma显示文摘	Shen GH Ghazizadeh M Kawanami O	2000	Br J Cancer2000，83，2：	1

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