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4篇 您的检索式:作者名="Gay Williams"
    题名 作者 年代 出处 被引量
1Ovarian Damages Produced by Aerosolized Fine Particulate Matter (PM2.5) Pollution in Mice: Possible Protective Medications and Mechanisms显示文摘Hui-Fang Gai Jian-Xiong An Xiao-Yan Qian Yong-Jie Wei John P Williams Guo-Lan Gao 2017Chinese Medical Journal2017,,12:13
2Uptake and mitochondrial dysfunction of alpha-synuclein in human astrocytes, cortical neurons and fibroblasts显示文摘The accumulation and aggregation of alpha-synuclein(α-syn)in several tissue including the brain is a major pathological hallmark in Parkinson’s disease(PD).In this study,we show that α-syn can be taken up by primary human cortical neurons,astrocytes and skin-derived fibroblasts in vitro.Our findings that brain and peripheral cells exposed to α-syn can lead to impaired mitochondrial function,leading to cellular degeneration and cell death,provides additional evidence for the involvement of mitochondrial dysfunction as a mechanism of toxicity of α-syn in human cells.Nady Braidy Wei-Ping Gai Ying Hua Xu Perminder Sachdev Gilles J Guillemin Xing-Mai Jiang J William O Ballard Martin P Horan Zhi Ming Fang Beng H Chong Daniel Kam Yin Chan 2013Translational Neurodegeneration2013,2,1:4
3Molecular and cellular mechanis of joint destruction in rheumatoid arthritis; two cellular mechanis explain joint destruction显示文摘Gays S renate EG William JK 1993Ann Rherm Dis1993,,:1
4Molecular and cellular mechanism of joint destruction in rheumatoid arthritis; two cellular mechanisms explain joint destruction显示文摘Gays S Renate EG William JK 1993Ann Rheum Dis1993,52,1:1
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