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| 1 | Zn-Mg and Zn-Cu alloys for stenting applications:From nanoscale mechanical characterization to in vitro degradation and biocompatibility显示文摘In the recent decades,zinc(Zn)and its alloys have been drawing attention as promising candidates for bioresorbable cardiovascular stents due to its degradation rate more suitable than magnesium(Mg)and iron(Fe)alloys.However,its mechanical properties need to be improved in order to meet the criteria for vascular stents.This work investigates the mechanical properties,biodegradability and biocompatibility of Zn-Mg and Zn-Cu alloys in order to determine a proper alloy composition for optimal stent performance.Nanoindentation measurements are performed to characterize the mechanical properties at the nanoscale as a function of the Zn microstructure variations induced by alloying.The biodegradation mechanisms are discussed and correlated to microstructure,mechanical performance and bacterial/cell response.Addition of Mg or Cu alloying elements refined the microstructure of Zn and enhanced yield strength(YS)and ultimate tensile strength(UTS)proportional to the volume fraction of secondary phases.Zn-1Mg showed the higher YS and UTS and better performance in terms of degradation stability in Hanks’solution.Zn-Cu alloys presented an antibacterial effect for S.aureus controlled by diffusion mechanisms and by contact.Biocompatibility was dependent on the degradation rate and the nature of the corrosion products. | Claudia García-Mintegui Laura Catalina Córdoba Judit Buxadera-Palomero Andrea Marquina Emilio Jiménez-Piqué Maria-Pau Ginebra JoséLuis Cortina Marta Pegueroles | 2021 | Bioactive Materials2021，6，12： | 4 |
| 2 | Important parameters in plasma jets for the production of RONS in liquids for plasma medicine: A brief review显示文摘Reactive oxygen and nitrogen species (RONS) are among the key factors in plasma medicine. They are generated by atmospheric plasmas in biological fluids, living tissues and in a variety of liquids. This ability of plasmas to create a delicate mix of RONS in liquids has been used to design remote or indirect treatments for oncological therapy by treating biological fluids by plasmas and putting them in contact with the tumour;Documented effects include selective cancer cell toxicity, even though the exact mechanisms involved are still under investigation. However, the 'right' dose for suitable therapeutical activity is crucial and still under debate. The wide variety of plasma sources hampers comparisons. This review focuses on atmospheric pressure plasma jets as the most studied plasma devices in plasma medicine and compiles the conditions employed to generate RONS in relevant liquids and the concentration ranges obtained. The concentrations of H2O2, NO2^-, NO3^- and short-lived oxygen species are compared critically to provide a useful overview for the reader. | Anna Khlyustova Cédric Labay Zdenko Machala Maria-Pau Ginebra Cristina Canal | 2019 | Frontiers of Chemical Science and Engineering2019，13，2： | 4 |
| 3 | Formation of α-Widmanst(a)tten structure:effects of grain size and cooling rate on the Widmanst(a)tten morphologies and on the mechanical properties in Ti6Al4V alloy显示文摘 | GIL F J GINEBRA M P | 2001 | Journal of Alloys and Compounds2001，329，： | 1 |
| 4 | Osteoblast-like cellular response to dynamic changes in the ionic extracellular environ- ment produced by calcium-deficient hydroxyapatite显示文摘 | Gustavsson J Ginebra MP Planell J | 2012 | J Mater Sci Mater Med2012，23，10： | 1 |
| 5 | Development and cell response of a new biodegradable composite scefold for guided bone regeneration 显示文摘 | Ginebra M P Driessens F C M Planell J A | 2004 | Journal of Materials Sci-ence: Materials in Medicine2004，，15： | 1 |
| 6 | Mechanical performance of acrylic bone cemems containing different radiopa-cifying agents显示文摘 | Ginebra MP Albuixech L Fernandez-Barragan E | 2002 | Biomaterials2002，23，8： | 1 |
| 7 | Compliance of an apatitic calcium phosphate short-term cement with the short-time clinical requirments in bone surgery,orthopaedics and dentistry显示文摘 | GINEBRA M P FEMKNDEZ E BOLTONG M G etal | 1994 | Clin Mater1994，17，： | 1 |
| 8 | Calcium phosphate cements as bone drug delivery systems:A review显示文摘 | Ginebra M P Traykova T Planell J A | 2006 | Journal of Controlled Release2006，113，2： | 1 |
| 9 | Calcium phosphate cements as bone drug delivery systems:a review 显示文摘 | MP Ginebra T Traykova JA Planell | 2006 | J Controlled Release2006，113，2： | 1 |
| 10 | Calcium phosphate bone cements for clinical applications-Part 2:Precipitate formation during setting reactions显示文摘 | Fernandez E Gil F J Ginebra M P | 1999 | J Mater Sci:Mater Med1999，10，： | 1 |
| 11 | 显示文摘 | Ginebra M P Traykova T Planell J A | 2006 | Journal of Controlled Release2006，113，： | 1 |
| 12 | Calcium phosphate cements as bone drug delivery systems:a review显示文摘 | Ginebra M P Traykova T Planell J A | 2006 | Journal of Controlled Release2006，113，2： | 1 |
| 13 | Influence of the modification of P/L ratio on a new formulation of acrylic hone cement显示文摘 | Pascual B Gurruchaga M Ginebra MP | 1999 | Biomaterials1999，20，5： | 1 |
| 14 | The effects of temperature on the behaviour of an apa-titic phosphate cement显示文摘 | Ginebra M P Fernandez E Driessens F C M | 1995 | J Mater SciMater Med1995，6，6： | 1 |
| 15 | Calcium phosphate cements:competitive drug carriers for the musculoskeletal system显示文摘 | Ginebra MP Traykova T Planell JA | 2006 | Biomaterials2006，27，10： | 1 |
| 16 | Calcium phosphate cements as bone drug delivery systems:a review显示文摘 | Ginebra M P Traykova T Planell J A | 2006 | J Control Release2006，113，2： | 1 |
| 17 | Fabrication of low temperature maeropores hydroxyapatite scaffolds by foaming and hydrolysis of an α-TCP paste 显示文摘 | Almirall A G Larreeq Delgado J A Martinez S Planell J A Ginebra M P | 2004 | Biomaterials2004，25，17： | 1 |
| 18 | Wet or dry mechanochemical synthesis of calcium phosphates? Influence of the water content on DCPD - CaO reaction kinetics 显示文摘 | Briak-BenAbdeslam H E Ginebra M P Vert M | 2008 | Acta Biomater2008，4，： | 1 |
| 19 | Calcium phosphate cements as bone drug delivery systems: a review 显示文摘 | Ginebra MP Traykova T Planell JA | 2006 | J Control Release2006，113，2： | 1 |
| 20 | Mechanical and rheological improvement of a calcium phosphate cement by the addition of a polymeric drug显示文摘 | Ginebra MP Rilliard A Fernandez E | 2001 | J Biomed Mater Res2001，57，1： | 1 |
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