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84篇 您的检索式:作者名="Goetz P J"
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1Update on Anti-Saccharomyces cerevisiae antibodies, anti-nuclear associated anti-neutrophil antibodies and antibodies to exocrine pancreas detected by indirect immunofluorescence as biomarkers in chronic inflammatory bowel diseases: Results of a multicent显示文摘AIM: Anti-Saccharomyces cerevisiae antibodies (ASCA), anti-nuclear associated anti-neutrophil antibodies (NANA) and antibodies to exocrine pancreas (PAB), are serological tools for discriminating Crohn’s disease (CrD) and ulcerative colitis (UC). Like CrD, coeliac disease (CoD) is an inflammatory bowel disease (IBD) associated with (auto) antibodies. Performing a multicenter study we primarily aimed to determine the performance of ASCA, NANA and PAB tests for IBD diagnosis in children and adults, and secondarily to evaluate the prevalence of these markers in CoD. METHODS: Sera of 109 patients with CrD, 78 with UC, 45 with CoD and 50 healthy blood donors were retrospectively included. ASCA, NANA and PAB were detected by indirect immunofluorescence (IIF). RESULTS: ASCA+/NANA- profile displayed a positive predictive value of 94.2% for CrD. Detection of ASCA was correlated with a more severe clinical profile of CrD and treatment of the disease did not influence their serum levels. ASCA positivity was found in 37.9% of active CoD.PAB were found in 36.7% CrD and 13.3% CoD patients and were not correlated with clinical features of CrD, except with an early onset of the disease. Fifteen CrD patients were ASCA negative and PAB positive. CONCLUSION: ASCA and PAB detected by IIF are specific markers for CrD although their presence does not rule out a possible active CoD. The combination of ASCA, NANA and PAB tests improves the sensitivity of immunological markers for CrD. Repeating ASCA, NANA, and PAB testing during the course of CrD has no clinical value.S Desplat-Jégo C Johanet A Escande J Goetz N Fabien N Olsson E Ballot J Sarles JJ Baudon JC Grimaud M Veyrac P Chamouard RL Humbel 2007World Journal of Gastroenterology2007,13,16:24
2New developments in acoustic and electroacoustic spectroscopy for characterizing concentrated dispersions 显示文摘DUKHIN A S GOETZ P J 2001Colloids and Surfaces: A Physicochemical and Engineering Aspects2001,192,3:1
3Pro-brain natriuretic peptide as marker of cardiovascular or pulmonary causes of dyspnea in patients with terminal parenchymal lung disease显示文摘GOETZE J P VIDEBAEK R BOESGAARD S 2004J Heart Lung Transplant2004,23,1:1
4Hyaluro- nan microspheres for sustained gene delivery and site-specific targeting 显示文摘YUN Y H GOETZ D J YELLEN P 2004Biomaterials2004,25,1:1
5Increased cardiac BNP expression associated with myocardial ischemia显示文摘Goetze J P 2003FASEB J2003,17,9:1
6Increased cardiac BNP expression associated with myocardial ischemia显示文摘GOETZE J P CHRISTOFFERSEN C PERKO M 2003FASEB J2003,17,:1
7Acoustic spectroscopy for concentrated polydisperse colloids with high density contrast 显示文摘DUKHIN A S GOETZ P J 1996Langmuir1996,12,21:1
8Increased cardiac BNP expression associated with myocardial ischemia显示文摘Goetze J P Christoffersen C Perko M 2003FASEB J2003,17,9:1
9Discrimi- nating between cardiac and pulmonary dysfunction in the general population with dyspnea by plasma pro-B- type natriuretic peptide 显示文摘Mogelvang R Goetze J Schnohr P 2008J Am Coil Cardiol2008,58,17:1
10MDS clinical diagnostic criteria for Parkinson's disease 显示文摘Postuma RB Berg D Stern M Poewe W Olanow CW Oertel W Obeso J Marek K Litvan I Lang AE Halliday G Goetz CG Gasser T Dubois B Chan P Bloem BR Adler CH Deuschl G 2015Mov Disord2015,30,12:1
11Study of the thermal denaturation of se- lected proteins of whey and egg by low resolution NMR 显示文摘Goetz J Koehler P 2005Food Seienee and Technology2005,38,5:1
12Plasma pro - B - type natriuretic peptide in the general population : screening for left ventricular hypertrophy and systolic dysfunction显示文摘GOETZE J P MOGELVANG R MAAGE L 2006Eur Heart J2006,27,24:1
13Caveolin-1 in tumor progression:the good,the bad and the ugly显示文摘Goetz J G Lajoie P Wiseman S M 2008Cancer Metastasis Rev2008,27,4:1
14The biology of cholecystokinin and gastrin peptides显示文摘REHFELD J F FRIIS-HANSEN L GOETZE J P etal 2007Current Topics in Medicinal Chemistry2007,7,12:1
15The impacts and implications of an intensifying fire regime on Alaskan boreal forest composition and albedo显示文摘BECK P S A GOETZ S J MACK M C 2011Global Change Biology2011,17,9:1
16Pharmacogenetics of tamoxifen biotransformation is associated with clinical outcomes of efficacy and hot flashes显示文摘GOETZ M P RAE J M SUMAN V J 2005J Clin Oncol2005,23,36:1
17Acute myocardial hypoxia increases BNP gene expression显示文摘Goetze J P Gore A Moller C H 2004FASEB J2004,18,15:1
18Local barrier dysfunction identified by confocal laser endomicroscopy predicts relapse in inflammatory bowel disease显示文摘R Kiesslich C A Duckworth D Moussata A Gloeckner L G Lim M Goetz D M Pritchard P R Galle M F Neurath A J M Watson 2012Gut2012,,8:1
19Hyaluronan microspheres for sustained gene delivery and site-specific targeting显示文摘 Goetz D J Yellen P 2004Biomaterials2004,25,1:1
20Image-guided ablation of painful meta static bone tumors: a new and effective approach to a difficult problem显示文摘Callstrom M R Charboneau J W Goetz M P Rubin J Atwell T D Farrell M A 2006Skeletal Radiol2006,35,:1
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