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121篇 您的检索式:作者名="Granger G"
    题名 作者 年代 出处 被引量
1妊娠期高血压免疫因子、肿瘤坏死因子α、血管紧张素Ⅱ1型受体自身抗体对妊娠可溶性fms样酪氨酸1和可溶性Endoglin产物的影响显示文摘最近研究发现先兆子痫中血管新生因子、可溶性fms样酪氨酸激酶(sFlt-1)和可溶性Endoglin(sEn-doglin)不平衡;然而尚不清楚它们过度分泌的启动机制。方法:长期给予怀孕大鼠肿瘤坏死因子α(tumor necrosis factor-α,TNF-α)或抗血管紧张素Ⅱ受体的自身抗体(AT1-AA),测定其循环和胎盘的sFlt-1和(或)sEndoglin以确定这些因素的免疫调节作用。Parrish MR Murphy SR Rutland S Wallace K Wenzel K Wallukat G Keiser S Ray LF Dechend R Martin JN Granger JP La Marca B 黄晓斌 2010中华高血压杂志2010,18,12:5
2针对患者利益的机器学习和人工智能研究:在透明性、可重复性、伦理和有效性等方面的20个关键问题显示文摘机器学习(ML)、人工智能(AI)和其他现代统计方法正为利用先前尚未开发且极速增长的数据资源提供新的机会,以期让患者获益。尽管目前正在进行许多有前景的研究,特别是在图像方面,但就文献整体而言还缺乏透明度、对可重复性清晰的阐述、对潜在伦理问题的探究,以及对有效性的明确验证。这些问题的存在有许多原因,其中最重要的一点(为此我们提供了初步解决方案)就是当前缺乏针对ML和AI的最佳实践指南。我们认为从事研究的跨学科团队和应用ML/AI影响健康的项目,将因解决有关透明度、可重复性、伦理和有效性(TREE)的一系列问题而受益。这里提出的20个关键问题为研究团队提供了一个研究设计、实施和报告框架;帮助编辑和同行评审专家评估文献的贡献;让患者、临床医生和政策制定者评估新发现可能会给患者带来的获益。Sebastian Vollmer Bilal A Mateen Gergo Bohner Franz J Kirdly Rayid Ghani Pall Jonsson Sarah Cumbers Adrian Jonas Katherine S L McAllister Puja Myles David Granger Mark Birse Richard Branson Karel G M Moons Gary S Collins John P A Chris Holmes Harry Hemingwayp 李峰(译) 徐磊(校) 赵邑(校) 2020英国医学杂志中文版2020,23,9:5
3胎盘生长因子抑制胎盘缺血引起的高血压显示文摘先兆子痫最有效的治疗是提前分娩出胎儿和胎盘。胎盘缺血的发生对先兆子痫发病有至关重要的影响,因为在动物或人类,子宫灌注压减少(reduced uterine perfusion pressure,RUPP)可诱发胎盘缺血/缺氧,刺激机体释放高血压胎盘因子进入母体循环。抗血管生成因子可溶性fms样酪氨酸激酶1(soluble fms-like tyrosine kinase-1,sFlt-1)可拮抗和减少有生物活性的血管内皮生长因子( vascular endothelial growth factor, VEGF)和胎盘生长因子( placental growth factor, PIGF),研究发现在RUPP大鼠和先兆子痫患者中,sFlt-1水平升高。刘莉 叶鹏 Spradley FT Tan AY Joo WS Daniels G Kussie P Karumanchi SA Granger JP 2016中华高血压杂志2016,24,2:2
4Cell adhesion molecules and isehemic stroke显示文摘Yilmaz G Granger DN 2008Neurol Res2008,30,8:1
5Characterization of multilayered piezoelectric ceramics for high power transducers显示文摘DUBUS B HAW G GRANGER C 2002Ultrasonics2002,40,:1
6Characteristics of Particulate Captured by A Rigid Tube Filter显示文摘Mabry G Kaems J Granger D 1997TMS Light Metals1997,,6:1
7Surfactant aggregates (solids) adsorbed on silica as stationary chromatographic phases: Structures and properties显示文摘BAKKER M G MORRIS T A TURNER G L GRANGER E 2000Journal of Chromatography B2000,743,1:1
8Characterization of multilayered piezoelectric ceramics for high power transducers显示文摘DUBUS B HAW G GRANGER C 2002Ultrasonics2002,40,:1
9Mechanisms of conversion of xanthine dehydrogenase to xanthine oxidase in ischemic rat liver and kidney显示文摘 HOLLWARTH M E GRANGER D N 1988Am J Physiol1988,254,:1
10Phylogeny and systematics of Prunus (Rosaceae) as determined by sequence analysis of ITS and the chloroplast trnL-trnF spacer DNA显示文摘BORTIRI E OH S H JIANG J G BAGGETT S GRANGER A WEEKS C BUCKINGHARM M POTTER D PARFITT D E 2001Systematic Botany2001,26,:1
11Leukocyte recruitment and isehemic brain in- jury显示文摘Yilmaz G Granger DN 2010Neuromolecular Med2010,12,2:1
12Ischeic injury in the cat small intestine:role of superoxide radicals显示文摘 BULKLEY G B GRANGER D N 1982Gastroenterology1982,82,:1
13Molecular char-acteristics of pbpla and pbp2b in clinical Streptococcus pneumoniae isolates in Quebec, Canada显示文摘Granger D Boily-Larouche G Turgeon P 2006J Antimicrob Chemother2006,57,1:1
14Mechanisms of conversion of xanthine dehydrogenase to xanthine oxidase in ischemic rat liver and kidney显示文摘McKelvey T G Hollwarth M E Granger D N 1988Am J Physiol Gastrointest Liver Physiol1988,254,:1
15Development and characterization of a clinically useful animal model of epithelial ovarian cancer in the Fischer344 rat显示文摘Rose G S Tocco L M Granger G A 1996Am J Obstet Gynecol1996,175,:1
16Friction and wear of aluminum-silicon alloys显示文摘SHABEL B S GRANGER D A TRUCKNER W G 1992ASM Handbook1992,18,:1
17(+)-And (-)-borneol:efficacious positive modulators of GABA action at human recombinant alpha 1 beta 2 gamma 2L GABA(A) receptors显示文摘GRANGER R E CAMPBELL E L JOHNSTON G A 2005Biochem Pharmacol2005,69,7:1
18Effects of candesartan on mortality and morbidity in patients with chronic heart failure: The CHARM-Overall programm显示文摘Pfeffer MA Swedberg G Granger C B 2003Lancet2003,362,:1
19Investigation of the catalytic performances of supported noble metal based catalysts in the NO+H2 reaction under lean conditions显示文摘ENGELMANN-PIREZ M GRANGER P LECLERCQ G 2005Catal Today2005,,:1
20Sweet cherry cuhivar identification by leafisozyme polymorphism显示文摘GRANGER A R CLARKE G R JACKSON J F 1993Theor Appl Gent1993,86,:1
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