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42篇 您的检索式:作者名="Griesenbach"
    题名 作者 年代 出处 被引量
1Low-frequency ultrasound increases non-viral gene transfer to the mouse lung显示文摘如果在 3035 kHz 的范围,低频率的超声(美国) 增加非病毒的基因转移到老鼠肺,学习的目的是估计。美国极大地在空气 / 织物接口由于大精力损失在肺被稀释。低频率的美国的优点,与高周波的美国相比:(i) 增加了成穴(为在房间膜的短暂毛孔的形成负责) 并且(ii ) 在肺穿入期间减少了精力损失。Cationic 类脂化合物 GL67/plasmid DNA (pDNA ) , polyethylenimine (PEI )/pDNA 和裸体 pDNA 经由 intranasal 灌输被交付,动物然后为 10 min 在 0.07 或 0.1 MPa 暴露于美国(sonoporation ) 。在这些条件下面,美国没提高 GL67 或调停 PEI 的 transfection。然而,它确实由约 4 褶层增加了裸体 pDNA 基因转移。重要地,这当 microbubbles 不在时被完成,它是关键的为通常使用高周波(1 MHz ) sonoporation 但是不能在临床上相关的安装承受 nebulization。肺出血也被估计并且出现以一种剂量依赖者方式与美国压力增加。这样,我们证实了低频率的美国能与裸体 pDNA 提高肺基因转移,这改进比更有效以前报导了 1 个 MHz 美国。Stefania Xenariou Hai-Dong Liang Uta Griesenbach Jie Zhu Raymond Farley Lucinda Somerton Charanjit Singh Peter K. Jeffery Ronald K. Scheule Seng H. Cheng Duncan M. Geddes Martin Blomley Eric W. F. W. Alton 2010Acta Biochimica et Biophysica Sinica2010,42,1:2
2Inflammation in cystic fibrosis airways:relationship to increased bacterial adherence显示文摘Scheid P Kempster L Griesenbach U 2001Eur Respir J2001,17,1:1
3Gene therapy progress and prospects:cystic fibrosis显示文摘Griesenbach U Geddes DM Alton EW 2006Gene Ther2006,13,14:1
4Critical appraisal of themouse model of myocardial infarction显示文摘DEGABRIELE N M GRIESENBACH U SATO K 2004Expphysiol2004,89,4:1
5Immunological hurdles to lung gene therapy 显示文摘FERRARI S GRIESENBACH U GEDDES DM 2003Clin Exp Immunol2003,132,1:1
6Use of ultrasound to enhance nonviral lung gene transfer in vivo 显示文摘Xenarious S Griesenbach U Liang HD 2007Gene Ther2007,14,9:1
7Use of ultrasound to enhance nonviral lung gene transfer in vivo 显示文摘Xenariou U Griesenbach U Liang HD 2007Gene Ther2007,14,9:1
8Gene transfer to the lung: lessons learned from more than 2 decades of CF gene therapy显示文摘GRIESENBACH U ALTON EW 2009Adv Drug Deliv Rev2009,61,2:1
9Progress and prospects : gene ther- apay clinical trials(part 1 ) 显示文摘Ahon E Ferraris Griesenbach U 2007Gene Ther2007,14,20:1
10Sendalvirus for gene therapy and vaccination显示文摘GRIESENBACH U INOUE M HASEGAWA M 2005Curr Opin Mol Ther2005,7,4:1
11Critical appraisal of the mouse model of myocardial infarction显示文摘Degabriele N M Griesenbach U Sato K 2004Exp Physiol2004,89,4:1
12Gene therapy progress and prospects: cystic fibrosis显示文摘GRIESENBACH U GEDDES DM ALTON EW 2006Gene Ther2006,13,14:1
13Beta-defensln ge- nomic copy number is not a modifier locus for cystic fibrosis 显示文摘Hollox EJ Davies J Griesenbach U 2005J Negat Results Biorned2005,4,:1
14Use of ultrasound to enhance nonviral lung gene transfer in vivo显示文摘 Griesenbach U Liang HD 2007Gene Ther2007,14,9:1
15Critical ap- praisal of the mouse model of myocardial infarction 显示文摘Degabriele NM Griesenbach U Sato K 2004Exp Physiol2004,89,4:1
16Advances in cystic fibrosis gene therapy显示文摘Griesenbach U Geddes DM Alton EW 2004Curr Opin Pulm Med2004,10,6:1
17Sendai virus for gene therapy and vaccination显示文摘Griesenbach U Inoue M Hasegawa M 2005Curr Opin Mol Ther2005,7,4:1
18Critical appraisal of the mouse model of myocardial infarction 显示文摘Degabriele NM Griesenbach U Sato K 2004Exp Physiol2004,89,4:1
19Critical appraisal of the mouse model of myocardial infarction 显示文摘Degabriele NM Griesenbach U Dato K 2004Exp Physiol2004,89,89:1
20Anti-inflammatory gene therapy directed at the airway epithelium 显示文摘Griesenbach U Scheid P Hillery E 2000Gene Ther2000,7,4:1
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