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| 1 | 中国妇女妊娠前后单纯服用叶酸对神经管畸形的预防效果显示文摘目的 评价妇女在妊娠前后服用单纯 40 0 μg叶酸增补剂对胎 /婴儿神经管畸形 (NTDs)的预防效果。方法 1993~ 1995年在中国北方的NTDs高发地区和南方的NTDs低发地区妇女增补叶酸的推广项目中 ,共募集从孕前或孕后任何时间开始服药的妇女 130 142名 ,未服药的妇女 1176 89名 ;设计的服药方法从婚检时开始到孕满 3个月为止 ,每天服用单纯叶酸片 40 0 μg ;最后对妇女的分娩结局进行监测并进行预防效果的对比评价研究。结果 服药组妇女生育的胎婴儿中共发现 10 2例NTDs ,对照组胎婴儿中共发现 173例NTDs。末次月经前募集的未服药妇女在孕 2 0周以后分娩的胎婴中NTDs发生率 ,北方为 4 8‰ (16 / 3 318) ,南方为 1 0‰ (2 8/ 2 82 6 5 ) ,而妊娠前后服药妇女组则分别为1 0‰ (13/ 13 0 12 )和 0 6‰ (34/ 5 86 38)。与末次月经前募集的未服药妇女组相比 ,北方服药妇女NTDs发生率明显降低 ,其中依从性大于 80 %的服药组妇女预防率达 85 % (95 %CI为 6 2 %~ 94% ) ,南方地区服叶酸的预防率为 41% (95 %CI为 3 %~ 6 4% )。结论 妇女在妊娠前后每天服用单纯叶酸 40 0 | 李竹 RobertJ Berry 李松 J David Erickson 王红 Cynthia A Moore 赵平 Joseph Mulinare 洪世欣 Lee-Yang C Wong 呼和牧人 Jacqueline Gindler 郝玲 Adolfo Correa 朱慧萍 Elaine Gunter | 2000 | 中华医学杂志2000，80，7： | 185 |
| 2 | Meats, protein and cancer显示文摘 | Gunter G C Kubnle Sbeila A Bingbam | 2010 | Nutrition and Health2010，，2： | 1 |
| 3 | Esti- mating irrigation water requirements in Europe显示文摘 | GUNTER W MARIJN VAN DER V ALBERTO A | 2009 | Journal of Hydrology2009，373，3： | 1 |
| 4 | Results of an International Round Robin for Serum and Whole-blood Folate 显示文摘 | GUNTER E W BOWMAN B A CAUDILL S P | 1996 | Clin Chem1996，42，： | 1 |
| 5 | Quantitation of insulin by CE and HPLC method comparison and validation显示文摘 | Kunkel A Gunter S Dette C | 1997 | J Chromatogr A1997，781，12： | 1 |
| 6 | Taking educational games se- riously: Using the RETAIN model to design endogenous fantasy into standalone educational games 显示文摘 | Gunter G A Kenny R F Vick E H | 2008 | Educational Technology Re- search and Development2008，56，56： | 1 |
| 7 | Effect of heat treatment and thermal cycling on transformation temperatures of ductile Cu-Al-Ni-Mn-B alloys显示文摘 | MORRIS M A GUNTER S | 1992 | Scripta Metallurgica et Materialia1992，26，11： | 1 |
| 8 | Scheduling with unexpected machine breakdowns显示文摘 | SUSANNE A GUNTER S | 2001 | Discrete Applied Mathematics2001，110，23： | 1 |
| 9 | Harvesting rib cartilage grafts for secondary rhinoplasty显示文摘 | Matin VP Landecker A Gunter JP | 2008 | Plast Reconstr Surg2008，121，4： | 1 |
| 10 | Formal verification of standards for distance vector routing protocols显示文摘 | Bhargavan K Obradovic D Gunter C A | 2002 | Journal of the ACM (JACM)2002，49，4： | 1 |
| 11 | Effects of supplementary selenium source on the blood parameters in beef cows and their nursing calves显示文摘 | Gunter S A Beck P A Hallford D M | 2013 | Biol Trace Elem Res2013，152，2： | 1 |
| 12 | Effects of supplementary selenium source on the performance and blood measurements in beef cows and their calves显示文摘 | Gunter S A Beck P A Phillips J M | 2003 | J Anim Sci2003，81，： | 1 |
| 13 | Insulin increases de novo steroidogenesis in prostate cancer cells显示文摘 | Lubik A A Gunter J H Hendy S C | 2011 | Cancer Res2011，71，17： | 1 |
| 14 | High resolution sediment and vegetation responses to younger Dryas climate change in varved lake sediments from Meerfelder Maar, Germany显示文摘 | BRAUER A ENDRES C GUNTER C | 1999 | Quaternary Sci Rev1999，18，3： | 1 |
| 15 | On the spatial scaling of soil moisture显示文摘 | Western A W Gunter B | 1999 | Journal of Hydrology1999，217，： | 1 |
| 16 | Accuracy of staging in early oesophageal cancer using high resolution endoscopy and high res- olution endosonography: a comparative, prospective, and blinded trial显示文摘 | May A GUnter E Roth F | 2004 | Gut2004，53，5： | 1 |
| 17 | Empirical analysis of freeway flow-density relationships 显示文摘 | Hall F L Allen B L Gunter M A | 1986 | Transportation Research Part A: Policy and Practice1986，20，3： | 1 |
| 18 | Performance Sport-education to Fair Play?Some Empirical and Theoretical Remarks 显示文摘 | GUNTER A PILZ | 1995 | Int Rev SocSport1995，，： | 1 |
| 19 | Recovery and complications after tonsillectomy in children: a comparison of ketorolac and morphine 显示文摘 | GUNTER J B VARUGHESE A M HARRINGTON J F | 1995 | Anesth Analg1995，81，6： | 1 |
| 20 | A reference model for requirements and specifications 显示文摘 | Cunter C A Gunter E L Jackson M | 2000 | IEEE Software2000，17，3： | 1 |
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