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| 1 | Hepatic steatosis is associated with an increased risk of carotid atherosclerosis显示文摘AIM: Although an association between helatic steatosis and vascular risk factors has been described, direct relationships between fatty liver and atherosclerosis have not yet been investigated. The aim of the present study has been to investigate those relationships.METHODS: The Study of Health in Pomerania examined a random population sample aged between 20 and 79 years.A study population of 4 222 subjects without hepatitis B and C infections and without liver cirrhosis was available for the present analysis. Hepatic steatosis was defined sonographically and intima-media thickness (IMT) as well as plaque prevalence were estimated by carotid ultrasound.RESULTS: The prevalence rate of hepatic steatosis was 29.9%. Among subjects aged ≥45 years, an association between hepatic steatosis and IMT of the carotid arteries was found in bivariate analysis, but not after adjustment for atherosclerotic risk factors. Individuals with fatty liver had more often carotid plaques than persons without fatty liver (plaque prevalence rate 76.8% vs 66.6%; P<0.001).This association persisted after adjustment for confounding factors and was predominantly present in subjects with no to mild alcohol consumption.CONCLUSION: There is an independent association between hepatic steatosis and carotid atherosclerotic plaques. Metabolic changes due to nonalcoholic fatty liver disease may explain this relationship. | Henry V(o|¨)lzke Daniel M.Robinson Volker Kleine Roland Deutscher Wolfgang Hoffmann Jan Lüdemann Ulf Schminke Christof Kessler Ulrich John | 2005 | World Journal of Gastroenterology2005，11，12： | 29 |
| 2 | Association between thyroid function and gallstone disease显示文摘AIM: To investigate those associations using data of the population-based Study of Health in Pomerania.METHODS: A study population of 3 749 residents aged 20-79 years without previously diagnosed thyroid disease was available for analyses. Serum TSH was used to assess thyroid function. Cholelithiasis was defined by either a prior history of cholecystectomy or the presence of gallstones on ultrasound. Logistic regression was performed to analyze independent associations between thyroid function and cholelithiasis.RESULTS: There were 385 persons (10.3%) with low (<0.3 mIU/L), 3 321 persons (88.6%) with normal and 43 persons (1.2%) with high serum TSH levels (>3 mIU/L).The proportion of cholelithiasis among males and females was 14.4% and 25.3%, respectively. Among males, there was an independent relation between high serum TSH and cholelithiasis (OR 3.77; 95%-CI 1.06-13.41; ,P<0.05). zAlso among males, there was a tendency towards an elevated risk of cholelithiasis in persons with low serum TSH (OR 1.40; 95%-CI 0.96-2.02; P = 0.07). In the female population, no such relation was identified.CONCLUSION: There is an association between thyroid and gallstone disease with a gender-specific relation between hypothyroidism and cholelithiasis. | Henry Vlzke Daniel M Robinson Ulrich John | 2005 | World Journal of Gastroenterology2005，11，35： | 8 |
| 3 | Multicausality in fatty liver disease:Is there a rationale to distinguish between alcoholic and non-alcoholic origin?显示文摘Apart from alcohol,there are other factors that may induce complications,which resemble alcohol-related liver disorders.In particular,obesity has been brought into focus as a risk factor for fatty liver disease.The term 'non-alcoholic' fatty liver disease is commonly used to distinguish between obesity-related and alcohol-related hepatic steatosis.This review uses the epidemiological perspective to critically assess whether it is necessary and useful to differentiate between alcoholic and 'nonalcoholic' fatty liver disease.The MEDLINE database was searched using the PubMed search engine,and a review of reference lists from original research and review articles was conducted.The concept to distinguish between alcoholic and 'non-alcoholic' fatty liver disease is mainly based on specific pathomechanisms.This concept has,however,several limitations including the common overlap between alcohol misuse and obesityrelated metabolic disorders and the non-consideration of additional causal factors.Both entities share similar histopathological patterns.Studies demonstrating differences in clinical presentation and outcome are often biased by selection.Risk factor reduction is the main principle of prevention and treatment of both disease forms.In conclusion,alcoholic and 'non-alcoholic' fatty liver diseases are one and the same disease caused by different risk factors.A shift from artificial categories to a more general approach to fatty liver disease as a multicausal disorder may optimize preventive strategies and help clinicians more effectively treat patients at the individual level. | Henry Vlzke | 2012 | World Journal of Gastroenterology2012，18，27： | 4 |
| 4 | Mechanisms involved in the inhibition of myoblast proliferation and differentiation by myostatin显示文摘 | Dominique Joulia Henri Bernardi Véronique Garandel Fanjaniriana Rabenoelina Barbara Vernus Gérard Cabello | 2003 | Experimental Cell Research2003，，2： | 3 |
| 5 | A taxonomic revision of Musa aurantiaca (Musaceae) in Southeast Asia显示文摘Since the initial description, the name Musa aurantiaca Baker (1893) has been unclear to most botanists. The aim of this study is to settle its true identity and to update the description. The plant is distributed in the regions of Upper Assam and Arunachal Pradesh, India, Northern Myanmar and Tibet, China where it occurs commonly but it is not mentioned in Chinese literature at all. In this paper, the authors also review the description and the literature history of M. aurantiaca from 1893 to the present. Musa aurantiaca Baker is typified here. | Markku HKKINEN Henry VRE | 2008 | 植物分类学报2008，46，1： | 3 |
| 6 | Perigastric extraskeletal Ewing's sarcoma: A case report显示文摘Ewing's sarcoma (ES) is a neoplasm of undifferentiated small round cells, which occurs in the bones and deep soft tissues of children and adolescents. We present a rare case of a 44-year-old woman with gastric ES presenting with epigastric pain and weight loss. Ultrasound and computed tomography scans indicated a solid/cystic mass in the pancreatic tail. At laparotomy, the tumor was found attached to the posterior surface of the stomach, completely free from the pancreas, with no lymphadenopathy or local metastases. The polynodal, partly pseudocystic, dark-red soft tumor was excised. Histopathology revealed an anaplastic small-round-cell tumor with strong membranous CD99 immunoexpression. Additionally, there was patchy immunostaining for S-100 protein, vimentin, protein gene product (PGP) 9.5 and neuron-specifi c enolase, and weak focal CD117 cytoplasmic immunoreactivity. The patient had no adjuvant chemotherapy; her postoperative recovery was uneventful, and she remains symptom-free, and without any sign of recurrence at 20 mo. To the best of our knowledge, this is only the third ever case of gastric ES. | Radoje B Colovic Nikica M Grubor Marjan T Micev Slavko V Matic Henry Dushan Edward Atkinson Stojan M Latincic | 2009 | World Journal of Gastroenterology2009，15，2： | 2 |
| 7 | Labeling of influenza viruses with synthetic fluorescent and biotin-labeled lipids显示文摘Direct labeling of virus particles is a powerful tool for the visualization of virus–cell interaction events. However, this technique involves the chemical modification of viral proteins that affects viral biological properties. Here we describe an alternative approach of influenza virus labeling that utilizes Function-Spacer-Lipid(FSL) constructs that can be gently inserted into the virus membrane. We assessed whether labeling with fluorescent(fluo-Ad-DOPE) or biotin-labeled(biot-CMG2-DOPE) probes has any deleterious effect on influenza virus hemagglutinin(HA) receptor specificity, neuraminidase(NA) activity, or replicative ability in vitro. Our data clearly show that neither construct significantly affected influenza virus infectivity or viral affinity to sialyl receptors. Neither construct influenced the NA activities of the influenza viruses tested, except the A/Puerto Rico/8/34(H1N1) strain. Our data indicate that lipid labeling provides a powerful tool to analyze influenza virus infection in vitro. | Natalia A Ilyushina Evgeny S Chernyy Elena Y Korchagina Aleksra S Gambaryan Stephen M Henry Nicolai V Bovin | 2014 | Virologica Sinica2014，29，4： | 2 |
| 8 | Duck Immune Responses to Riemerella anatipestifer Vaccines显示文摘 | Higgins D A R R Henry Z V Kounev | 2000 | Developmental and Comparative Immunology2000，24，： | 1 |
| 9 | Tourmaline as a petrogenetic indicator mineral:an example from the staurolite-grade metapelites of NW Maine显示文摘 | Henry D J Guidotti C V | 1985 | American Mineralogist1985，70，： | 1 |
| 10 | Microbial status of apical root ca- nal system of human mandibular first molar with primary apical pe- riodontitis after' one- visit' endodontic treatment显示文摘 | Nair PNR Henry S Cano V | 2005 | Oral Surg O- ral Med Oral Pathol Oral Radiol Endod2005，99，2： | 1 |
| 11 | Sub- cellular distribution of the foot-and-mouth disease virus 3A protein in cells infected with viruses enco- ding wild-type and bovine-attenuated forms of 3A显示文摘 | O'Donnell V K Paeheco J M Henry T M | 2001 | Virology2001，287，1： | 1 |
| 12 | Role of nonstructural proteins 3A and 3B in host range and pathogenicity of foot-and-mouth disease virus显示文摘 | Pacheco J M Henry T M O'Donnell V K | 2003 | JVirol2003，77，24： | 1 |
| 13 | Activated charcoal, emesis, and gastric lavage in aspirin overdose显示文摘 | Danel V Henry J A Glucksman E | 1988 | Br Med J (Clin Res Ed)1988，296，5： | 1 |
| 14 | Two synchronous somatostatinomas of the duodenum and pancreatic head in one patient显示文摘Somatostatinomas are extremely rare neuroendocrine tumors of the gastrointestinal tract,f irst described in the pancreas in 1977 and in the duodenum in 1979.They may be functional and cause somatostatinoma or inhibi-tory syndrome,but more frequently are non-functioning pancreatic endocrine tumors that produce somatostatin alone.They are usually single,malignant,large lesions,frequently associated with metastases,and generally with poor prognosis.We present the unique case of a 57-year-old woman with two synchronous non-function-ing somatostatinomas,one solid duodenal lesion and one cystic lesion within the head of the pancreas,that were successfully resected with a pylorus-preserving Whipple's procedure.No secondaries were found in the liver,or in any of the removed regional lymph nodes.The patient had an uneventful recovery,and remains well and symptom-free at 18 mo postoperatively.This is an extremely rare case of a patient with two synchro-nous somatostatinomas of the duodenum and the pancreas.The condition is discussed with reference to the literature. | Radoje B olovi Slavko V Mati Marjan T Micev Nikica M Grubor Henry Dushan Atkinson Stojan M Latini | 2009 | World Journal of Gastroenterology2009，15，46： | 1 |
| 15 | Sub-cellular distribution of the foot-and-mouth disease virus 3A protein in cells infected with viruses encoding wild-type and bovine-attenuated forms of 3A显示文摘 | O'DONNELL V K PACHECOJ M HENRY T M | 2001 | Virology2001，287，1： | 1 |
| 16 | Dendritic cells genetically engineered to express IL-10 induce long-lasting antigen-specific tolerance in experimental asthma显示文摘 | Henry E Desmet CJ Garze V | 2008 | J Immunol2008，181，： | 1 |
| 17 | The Tisaturation surface for low-to-medium pressure metapelitic biotites:Implications for geo- thermonmetry and Ti-substitution mechanisms显示文摘 | Henry D J Guidotti C V Thomoson J A | | Am Mineral0，90，： | 1 |
| 18 | Overexpression of the Bacillus thuringiensis (Bt) Cry2Aa2 protein in chloroplast confers resistance to plants against susceptible and Bt resistant insects 显示文摘 | MADHURI K HENRY D SAM V | 1999 | Proc NatlAcadSci USA1999，96，： | 1 |
| 19 | A multiplex RT-PCR assay capable of distinguishing beet necrotic yellow vein virus types A and B 显示文摘 | Ratti C Clover G R G Autonell C R Harju V A Henry C M | 2005 | J Virol Methods2005，124，： | 1 |
| 20 | Efficacy of GLP-1 re- ceptor agonists and DPP-4 inhibitors: meta-analysis and sys- tematic review显示文摘 | Aroda V R Henry R R Han J | 2012 | Clin Ther2012，34，6： | 1 |
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