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| 1 | Finite Groups in Which all Nonlinear Irreducible Characters have Distinct Degrees 显示文摘 | Berkovich Y Chillag D Herzog M | 1992 | Proc Amer Math Soc1992，106，： | 2 |
| 2 | Serotonin type 3 receptor subunit gene polymorphisms associated with psychosomatic symptoms in irritable bowel syndrome:A multicenter retrospective study显示文摘BACKGROUND Single-nucleotide polymorphisms(SNPs)of the serotonin type 3 receptor subunit(HTR3)genes have been associated with psychosomatic symptoms,but it is not clear whether these associations exist in irritable bowel syndrome(IBS).AIM To assess the association of HTR3 polymorphisms with depressive,anxiety,and somatization symptoms in individuals with IBS.METHODS In this retrospective study,623 participants with IBS were recruited from five specialty centers in Germany,Sweden,the United States,the United Kingdom,and Ireland.Depressive,anxiety,and somatization symptoms and sociodemographic characteristics were collected.Four functional SNPs—HTR3A c.-42C>T,HTR3B c.386A>C,HTR3C c.489C>A,and HTR3E c.*76G>A—were genotyped and analyzed using the dominant and recessive models.We also performed separate analyses for sex and IBS subtypes.SNP scores were calculated as the number of minor alleles of the SNPs above.The impact of HTR3C c.489C>A was tested by radioligand-binding and calcium influx assays.RESULTS Depressive and anxiety symptoms significantly worsened with increasing numbers of minor HTR3C c.489C>A alleles in the dominant model(F_(depressive)=7.475,P_(depressive)=0.006;F_(anxiety)=6.535,P_(anxiety)=0.011).A higher SNP score(range 0-6)was linked to a worsened depressive symptoms score(F=7.710,P-linear trend=0.006)in IBS.The potential relevance of the HTR3C SNP was corroborated,showing changes in the expression level of 5-HT3AC variant receptors.CONCLUSION We have provided the first evidence that HTR3C c.489C>A is involved in depressive and anxiety symptoms in individuals with IBS.The SNP score indicated that an increasing number of minor alleles is linked to the worsening of depressive symptoms in IBS. | Sabrina Berens Yuanjun Dong Nikola Fritz Jutta Walstab Mauro D'Amato Tenghao Zheng Verena Wahl Felix Boekstegers Justo Lorenzo Bermejo Cristina Martinez Stefanie Schmitteckert Egbert Clevers Felicitas Engel Annika Gauss Wolfgang Herzog Robin Spiller Miriam Goebel-Stengel Hubert Mönnikes Viola Andresen Frieling Thomas Jutta Keller Christian Pehl Christoph Stein-Thöringer Gerard Clarke Timothy G Dinan Eamonn M Quigley Gregory Sayuk Magnus Simrén Jonas Tesarz Gudrun Rappold Lukas van Oudenhove Rainer Schaefert Beate Niesler | 2022 | World Journal of Gastroenterology2022，28，21： | 2 |
| 3 | Strand spaces:Proving security protocols correct 显示文摘 | Thayer F J Herzog J C Guttman J D | 1999 | Journal of Computer Security1999，7，23： | 2 |
| 4 | Effect of 5-azacytidine on differentiation and DNA methylation in human promyelocytic leukemia cells显示文摘 | Christman JK Mendelsohn N Herzog D | 1983 | Cancer Res1983，43，： | 1 |
| 5 | Mortality in eating disorders:a descriptive study显示文摘 | Greenwood D N Dorer D J | 2000 | IntJ Eat Disord2000，28，1： | 1 |
| 6 | The role of muscles in joint degeneration and os- teoarthritis显示文摘 | Herzog W Lonqino D | 2007 | J Biomech2007，40，1： | 1 |
| 7 | Strand spaces:Proving security protocols correct显示文摘 | Fàbrega F J T Herzog J C Guttman J D | 1999 | Journal of Computer Security1999，7，23： | 1 |
| 8 | NPY and Y receptors:lessons from transgenic and knockout models显示文摘 | LIN S BOEY D HERZOG H | | 0，，： | 1 |
| 9 | The benefits of maximum efficiency hydraulic fluids显示文摘 | HERZOG S N NEVEU C D PLACEK D G | 2005 | Machinery Lubrication2005，7，： | 1 |
| 10 | Global 2-D intercomparison of sectional and modal aerosol modules 显示文摘 | Weisenstein D K Penner J E Herzog M | 2007 | Atmos Chem Phys2007，7，： | 1 |
| 11 | Determination of trace metals by underpotential deposition-stripping voltammetry at solid electrodes显示文摘 | Herzog G Arrigan D W M | 2005 | Trends Anal Chem2005，24，3： | 1 |
| 12 | Strand Spaces:proving security protocols correct显示文摘 | Thayer F J Herzog J C and Guttman J D | 1999 | Journal of Computer Security1999，7，23： | 1 |
| 13 | Plasticity of Marrow-derived Stem Cells显示文摘 | Herzog E L Chai L Krause D S | 2003 | Blood2003，102，： | 1 |
| 14 | Strand spaces:Proving security protocols correct显示文摘 | HERZOG J C GUTTMAN J D | 1999 | Journal of Computer Security1999，7，23： | 1 |
| 15 | Macrostructure of asphaltene dispersions by small-angle X-ray scattering显示文摘 | HERZOG P TCHOUBAR D ESPINANT D | 1988 | Fuel1988，67，2： | 1 |
| 16 | Strand space: proving security protocols correct显示文摘 | FABREGA F J T HERZOG J C GUrlTMAN J D | 1999 | Journal of Computer Security1999，7，3： | 1 |
| 17 | Spatial behaviour is driven by proximal cues even in mildly impaired Parkinson's disease 显示文摘 | Leplow B Holl D Zeng L Herzog A Behrens K Mehdorn M | 2002 | Neuropsyehologia2002，40，： | 1 |
| 18 | Strand spaces:proving security protocols correct显示文摘 | Thayer F J Herzog J C Guttman J D | 1999 | Journal of Computer Security1999，7，23： | 1 |
| 19 | Genetic clustering of Borna disease virus natural animal isolates, laboratory and vaccine strains strongly reflects their regional geographical origin 显示文摘 | Jolanta Kolodziejek Ralf D rrwald Sibylle Herzog | 2005 | J Gen Virol2005，86，2： | 1 |
| 20 | Strand spaces:proving security protocols correct显示文摘 | Thayer F Herzog J C Guttman J D | 1999 | Journal ofComputer Security1999，7，2： | 1 |
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