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129篇 您的检索式：作者名="Ham C J"

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	题名	作者	年代	出处	被引量
1	Role of E3 ubiquitin ligases in lung cancer显示文摘E3 ubiquitin ligases are a large family of proteins that catalyze the ubiquitination of many protein substrates for targeted degradation by the 26S proteasome.Therefore,E3 ubiquitin ligases play an essential role in a variety of biological processes including cell cycle regulation,proliferation and apoptosis.E3 ubiquitin ligases are often found overexpressed in human cancers,including lung cancer,and their deregulation has been shown to contribute to cancer development.However,the lack of specific inhibitors in clinical trials is a major issue in targeting E3 ubiquitin ligases with currently only one E3 ubiquitin ligase inhibitor being tested in the clinical setting.In this review,we focus on E3 ubiquitin ligases that have been found deregulated in lung cancer.Furthermore,we discuss the processes in which they are involved and evaluate them as potential anti-cancer targets.By better understanding the mechanisms by which E3 ubiquitin ligases regulate biological processes and their exact role in carcinogenesis,we can improve the development of specific E3 ubiquitin ligase inhibitors and pave the way for novel treatment strategies for cancer patients.	Barbara C Snoek Leonie HAM de Wilt Gerrit Jansen Godefridus J Peters	2013	World Journal of Clinical Oncology2013，4，3：	5
2	Prevalence,Capsular Type and Antimicrobial Susceptibility of Streptococcus suis Isolated from Slaughter Pigs in Korea显示文摘	Han D U Choi C Ham H J	2001	Can J Vet Res2001，65，3：	1
3	Feasibility of a constructed wetland and wastewater stabilisation pond system as a sewage reclamation system for agricultural reuse in a decentralised rural area 显示文摘	Ham J H Yoon C G Jeon J H	2007	Water Science & Technology2007，55，12：	1
4	An Analysis of Addition and Subtraction Word Problems in American and Soviet Elementary Mathematics Textbooks 显示文摘	Stigler J W Fuson K C Ham M	1986	Cognition and Instruction1986，，3：	1
5	Polymorphism of the beta (2)-adrenoceptor in COPD in Chinese subjects 显示文摘	Ho L I Ham H J Chen C J	2001	Chest2001，120，5：	1
6	Spatial separation of HLADM/HLA-DR interactions within MIIC and phagosome-induced immune escape显示文摘	Zwart W Griekspoor A Kuijl C Marsman M van Rheenen J Janssen H Calafat J van Ham M Janssen L van Lith M Jalink K Neefjes J	2005	Immunity2005，22，：	1
7	A Statistical analysis of the Los Angeles ambient carbon monoxide data 1955-1972 显示文摘	Tiao G C Box G E P Hamming W J	1975	J Air Pollut Control Assoc1975，24，：	1
8	Interference minimized multi-path routing with congestion control in wireless sensor networks for high-rate streaming显示文摘	Teo J Y Ha Y J Ham C K	2008	IEEE Transactions on Mobile Computing2008，7，9：	1
9	Design of DL-based certificateless digital signature显示文摘	Ham L Ren J Lin C	2009	The Journal of Systems and Software2009，82，：	1
10	A new selection system for pepper regeneration by mannose显示文摘	Kim J Y Jung M Kim H S Lee Y H Choi S H Lim Y P Min B W Yang S G Ham C H		0，，03：	1
11	Genome sequence and analysis of the tuber crop potato显示文摘	Xu X Pan S Cheng S Zhang B Mu D Ni P Zhang G Yang S Li R Wang J Orjeda G Guzman F Tones M Lnzano R Ponce O Martinez D De la Cruz G Chakrabarti S K Patil V U Skryabin K G Kuznetsov B B Ravin N V Kolganova T V Beletsky A V Mardanov A V Di Genova A Bolser D M Martin D M Li G Yang Y Kuang H Hu Q Xiong X Bishop G J Sagredo B Mejia N Zagorski W Gromadka R Gawor J Szczesny P Huang S Zhang Z Liang C He J Li Y He Y Xu J Zhang Y Xie B Du Y Qu D Bonierbale M Ghislain M Herrera Mdel R Giuliano G Pietrella M Perrotta G Faeella P O 'Brien K Feingold S E Barreiro L E Massa G A Diambra L Whitty B R Vaillancourt B Lin H Massa A N Geoffroy M Lundback S DellaPenna D Buell C R Sharma S K Marshall D F Waugh R Bryan G J Destefanis M Nagy I Milbourne D Thomson S J Fiefs M Jacobs J M Nielsen K L Sonderkaer M Iovene M Tortes G A Jiang J Veilleux R E Bachem C W de Boer J Bonn T Kloosterman B van Eck H Datema E Hekkert B Goverse A van Ham R C Visser R G	2011	Nature2011，475，7355：	1
12	Responses of soil respiration to clipping and grazing in a tallgrass prairie显示文摘	Bremer D J Ham J M Owensby C E	1998	Jour nal of Environmental Quality1998，27，：	1
13	A probabilistic framework for SVM regression and error bar estimation显示文摘	Gao J B Gunn S R Ham's C J	2002	Machine Learning2002，46，：	1
14	The feasibility of mega container vessels显示文摘	HAM J C van	2005	European Transport/Trasporti Europei2005，，2526：	1
15	Nonlinear Robust Control Design for Levitation and Propulsion of a Maglev System显示文摘	Kaloust J Ham C Siehling J	2004	IEE Proceedings-Control Theory and Applications2004，151，4：	1
16	Effect of antibiotics in fibrin sealant on healing colonic anastomoses in the rat 显示文摘	Vander Ham A C Kort W J Weijma I M	1992	BrJSurg1992，79，：	1
17	A probabilistic framework for SVM regression and Error Bar Estimation显示文摘	Gao J B Gunn S R Ham's C J	2002	Machine Learning2002，46，：	1
18	Model development for nutrient loading estimates from paddy rice fields in Korea显示文摘	JEON J H YOON C G HAM J H	2004	Journal of Environmental Science and Health-Part B:Pesticides Food Contaminants and Agricultural Wastes2004，39，56：	1
19	PP II:A novel pathogen-induced basic regionleucine zipper (bZIP) transcription factor from pepper显示文摘	Lee S J Lee M Y Yi S Y Oh S K Choi S H Her N H Choi D Min B W Yang S G Ham C H		0，，：	1
20	Nonlinear robust control design for levitation and propulsion ofmaglev system 显示文摘	Kaloust J Ham C Sieghling J	2004	IEEE2004，151，4：	1

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